Discoidin Domain Receptor 1
"Discoidin Domain Receptor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A discoidin domain receptor for FIBRILLAR COLLAGEN that functions in a variety of cellular processes. For example, it regulates cell attachment to the EXTRACELLULAR MATRIX, remodeling of the extracellular matrix, CELL MIGRATION; CELL DIFFERENTIATION; CELL PROLIFERATION; and CELL SURVIVAL.
| Descriptor ID |
D000070819
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| MeSH Number(s) |
D08.811.913.696.620.682.725.400.005.500 D12.776.543.750.630.005.500 D12.776.543.750.685.050.500 D12.776.543.750.705.880.300.500
|
| Concept/Terms |
Discoidin Domain Receptor 1- Discoidin Domain Receptor 1
- Discoidin Domain Receptor Tyrosine Kinase 1
- Discoidin Domain Receptor Family, Member 1 Protein
- DDR1 Protein
- Protein, DDR1
- CD167 Antigen
- Antigen, CD167
|
Below are MeSH descriptors whose meaning is more general than "Discoidin Domain Receptor 1".
Below are MeSH descriptors whose meaning is more specific than "Discoidin Domain Receptor 1".
This graph shows the total number of publications written about "Discoidin Domain Receptor 1" by people in this website by year, and whether "Discoidin Domain Receptor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Discoidin Domain Receptor 1" by people in Profiles.
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DDR1-induced neutrophil extracellular traps drive pancreatic cancer metastasis. JCI Insight. 2021 09 08; 6(17).
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Combined inhibition of DDR1 and CDK4/6 induces synergistic effects in ER-positive, HER2-negative breast cancer with PIK3CA/AKT1 mutations. Oncogene. 2021 07; 40(26):4425-4439.
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Collagen-rich airway smooth muscle cells are a metastatic niche for tumor colonization in the lung. Nat Commun. 2019 05 13; 10(1):2131.
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The prognostic effects of somatic mutations in ER-positive breast cancer. Nat Commun. 2018 09 04; 9(1):3476.
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Inhibition of Discoidin Domain Receptor 1 Reduces Collagen-mediated Tumorigenicity in Pancreatic Ductal Adenocarcinoma. Mol Cancer Ther. 2017 11; 16(11):2473-2485.
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Multi-organ Site Metastatic Reactivation Mediated by Non-canonical Discoidin Domain Receptor 1 Signaling. Cell. 2016 Jun 30; 166(1):47-62.
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Integrative DNA methylation and gene expression analysis identifies discoidin domain receptor 1 association with idiopathic nonobstructive azoospermia. Fertil Steril. 2014 Oct; 102(4):968-973.e3.
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Wnt5a is required for proper mammary gland development and TGF-beta-mediated inhibition of ductal growth. Development. 2007 Nov; 134(21):3929-39.
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M?nage-?-trois 1 is critical for the transcriptional function of PPARgamma coactivator 1. Cell Metab. 2007 Feb; 5(2):129-42.
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Identification and chromosomal mapping of a receptor tyrosine kinase with a putative phospholipid binding sequence in its ectodomain. Oncogene. 1994 Jan; 9(1):211-9.