"Nogo Receptor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A high affinity receptor for myelin-associated inhibitors (MAIs) that include NOGO-A PROTEIN; OLIGODENDROCYTE MYELIN GLYCOPROTEIN; and MYELIN-ASSOCIATED GLYCOPROTEIN. It is expressed primarily by neurons in the brain and OLFACTORY BULBS. During embryonic development, it is expressed in the PERIPHERAL NERVOUS SYSTEM. It localizes to GROWTH CONES and may inhibit neurite outgrowth following SPINAL INJURY.
| Descriptor ID |
D000070816
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| MeSH Number(s) |
D12.776.395.550.448.738.500 D12.776.543.484.500.738.500 D12.776.543.550.418.738.500 D12.776.543.750.600.500 D12.776.631.651.500
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| Concept/Terms |
Nogo Receptor 1- Nogo Receptor 1
- Nogo-66 Receptor
- Nogo 66 Receptor
- Receptor, Nogo-66
- NgR1 Protein
- Protein, NgR1
- Reticulon-4 Receptor
- Receptor, Reticulon-4
- Reticulon 4 Receptor
- RTN4R Protein
- Protein, RTN4R
|
Below are MeSH descriptors whose meaning is more general than "Nogo Receptor 1".
Below are MeSH descriptors whose meaning is more specific than "Nogo Receptor 1".
This graph shows the total number of publications written about "Nogo Receptor 1" by people in this website by year, and whether "Nogo Receptor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nogo Receptor 1" by people in Profiles.
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Assessment of Nogo-66 receptor 1 function in vivo after spinal cord injury. Neurosurgery. 2014 Jul; 75(1):51-60.
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Inhibition of Nogo-66 receptor 1 enhances recovery of cognitive function after traumatic brain injury in mice. J Neurotrauma. 2013 Feb 15; 30(4):247-58.
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Molecular basis of the interactions of the Nogo-66 receptor and its homolog NgR2 with myelin-associated glycoprotein: development of NgROMNI-Fc, a novel antagonist of CNS myelin inhibition. J Neurosci. 2009 May 06; 29(18):5768-83.
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Genetic variants of Nogo-66 receptor with possible association to schizophrenia block myelin inhibition of axon growth. J Neurosci. 2008 Dec 03; 28(49):13161-72.
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Mechanisms of CNS myelin inhibition: evidence for distinct and neuronal cell type specific receptor systems. Restor Neurol Neurosci. 2008; 26(2-3):97-115.
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Alzheimer precursor protein interaction with the Nogo-66 receptor reduces amyloid-beta plaque deposition. J Neurosci. 2006 Feb 01; 26(5):1386-95.
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Transgenic inhibition of Nogo-66 receptor function allows axonal sprouting and improved locomotion after spinal injury. Mol Cell Neurosci. 2005 May; 29(1):26-39.
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Mutations of the Nogo-66 receptor (RTN4R) gene in schizophrenia. Hum Mutat. 2004 Dec; 24(6):534-5.
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Nogo-66 receptor prevents raphespinal and rubrospinal axon regeneration and limits functional recovery from spinal cord injury. Neuron. 2004 Oct 28; 44(3):439-51.
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Nogo receptor antagonism promotes stroke recovery by enhancing axonal plasticity. J Neurosci. 2004 Jul 07; 24(27):6209-17.