"Ranolazine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An acetanilide and piperazine derivative that functions as a SODIUM CHANNEL BLOCKER and prevents the release of enzymes during MYOCARDIAL ISCHEMIA. It is used in the treatment of ANGINA PECTORIS.
| Descriptor ID |
D000069458
|
| MeSH Number(s) |
D02.065.199.092.850 D02.092.146.113.092.850 D03.383.606.841
|
| Concept/Terms |
Ranolazine- Ranolazine
- N-(2,6-dimethylphenyl)-4-(2-hydroxy-3-(2-methoxyphenoxy)propyl)-1-piperazineacetamide
- Renolazine
Ranolazine Hydrochloride- Ranolazine Hydrochloride
- Hydrochloride, Ranolazine
- Ranolazine Dihydrochloride
- Dihydrochloride, Ranolazine
- Ranolazine HCl
- HCl, Ranolazine
RS 43285- RS 43285
- 43285, RS
- RS-43285
- RS43285
|
Below are MeSH descriptors whose meaning is more general than "Ranolazine".
Below are MeSH descriptors whose meaning is more specific than "Ranolazine".
This graph shows the total number of publications written about "Ranolazine" by people in this website by year, and whether "Ranolazine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 2 | 0 | 2 |
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Below are the most recent publications written about "Ranolazine" by people in Profiles.
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A fatal ranolazine overdose after an intentional ingestion. Clin Toxicol (Phila). 2020 03; 58(3):213-214.
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Ranolazine prevents pressure overload-induced cardiac hypertrophy and heart failure by restoring aberrant Na+ and Ca2+ handling. J Cell Physiol. 2019 07; 234(7):11587-11601.
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Ranolazine-Associated Myoclonus. Am J Ther. 2018 Jul/Aug; 25(4):e507-e508.
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The combined effects of ranolazine and dronedarone on human atrial and ventricular electrophysiology. J Mol Cell Cardiol. 2016 05; 94:95-106.
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Myopathy during treatment with the antianginal drug ranolazine. J Neurol Sci. 2014 Dec 15; 347(1-2):380-2.
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Clinical experience with ranolazine in a veteran population with chronic stable angina. Ann Pharmacother. 2012 Jan; 46(1):42-50.
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New antiarrhythmic drugs for treatment of atrial fibrillation. Lancet. 2010 Apr 03; 375(9721):1212-23.
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Myocardial metabolism: a new target for the treatment of heart disease? Curr Hypertens Rep. 2004 Dec; 6(6):414-5.
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Cardiac metabolism as a target for the treatment of heart failure. Circulation. 2004 Aug 24; 110(8):894-6.