"Histamine H2 Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that selectively bind to but do not activate histamine H2 receptors, thereby blocking the actions of histamine. Their clinically most important action is the inhibition of acid secretion in the treatment of gastrointestinal ulcers. Smooth muscle may also be affected. Some drugs in this class have strong effects in the central nervous system, but these actions are not well understood.
| Descriptor ID |
D006635
|
| MeSH Number(s) |
D27.505.519.625.375.425.425 D27.505.696.577.375.425.425
|
| Concept/Terms |
Histamine H2 Antagonists- Histamine H2 Antagonists
- Receptor Blockaders, H2
- Blockaders, Histamine H2 Receptor
- Histamine H2 Receptor Blockaders
- Histamine H2 Blockers
- Blockers, Histamine H2
- H2 Blockers, Histamine
- Receptor Antagonists, Histamine H2
- Histamine H2 Receptor Antagonists
- Antagonists, Histamine H2
- H2 Antagonists, Histamine
- H2 Receptor Blockaders
- Blockaders, H2 Receptor
- Antihistaminics, H2
- H2 Antihistaminics
|
Below are MeSH descriptors whose meaning is more general than "Histamine H2 Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Histamine H2 Antagonists".
This graph shows the total number of publications written about "Histamine H2 Antagonists" by people in this website by year, and whether "Histamine H2 Antagonists" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 2 | 0 | 2 |
| 2004 | 2 | 3 | 5 |
| 2005 | 2 | 1 | 3 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2012 | 2 | 0 | 2 |
| 2013 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 3 | 0 | 3 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 2 | 3 |
| 2022 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Histamine H2 Antagonists" by people in Profiles.
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Prescriptions of anti-reflux drugs in neonatology and neonatal intensive care units: A large multicentre observational study (2014-2022). Br J Clin Pharmacol. 2024 Dec; 90(12):3201-3211.
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Antacid Therapy in Coronary Artery Disease and Heart Failure: Proton Pump Inhibitors vs. H2 Receptor Blockers. Cardiovasc Drugs Ther. 2024 Feb; 38(1):181-189.
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Stress Ulcer Prophylaxis for ICU Patients. JAMA. 2020 07 07; 324(1):101.
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Acid-suppressive medications and risk of colorectal cancer: results from three large prospective cohort studies. Br J Cancer. 2020 09; 123(5):844-851.
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Consensus treatment plans for periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome (PFAPA): a framework to evaluate treatment responses from the childhood arthritis and rheumatology research alliance (CARRA) PFAPA work group. Pediatr Rheumatol Online J. 2020 Apr 15; 18(1):31.
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Systematic review with meta-analysis: the risks of proton pump inhibitors during pregnancy. Aliment Pharmacol Ther. 2020 02; 51(4):410-420.
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Long-term proton pump inhibitor usage and the association with pancreatic cancer in Sweden. J Gastroenterol. 2020 Apr; 55(4):453-461.
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Use of Acid-Suppressant Medications After Diagnosis Increases Mortality in a Subset of Gastrointestinal Cancer Patients. Dig Dis Sci. 2020 09; 65(9):2691-2699.
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Pulmonary findings in infants with cystic fibrosis during the first year of life: Results from the Baby Observational and Nutrition Study (BONUS) cohort study. Pediatr Pulmonol. 2019 05; 54(5):581-586.
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Proton Pump Inhibitors, Histamine-2 Receptor Antagonists, and Hip Fracture Risk among Patients on Hemodialysis. Clin J Am Soc Nephrol. 2018 10 08; 13(10):1534-1541.