"Histamine H1 Antagonists" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood.
| Descriptor ID |
D006634
|
| MeSH Number(s) |
D27.505.519.625.375.425.400 D27.505.696.577.375.425.400
|
| Concept/Terms |
Histamine H1 Antagonists- Histamine H1 Antagonists
- H1 Antagonists, Histamine
- Antagonists, Histamine H1 Receptor
- Antihistaminics, H1
- H1 Antihistaminics
- Receptor Blockaders, H1
- H1 Receptor Blockaders
- Histamine H1 Blockers
- Histamine H1 Receptor Antagonists
- Histamine H1 Receptor Blockaders
- Antagonists, Histamine H1
- Blockaders, Histamine H1 Receptor
Antihistamines, Classical- Antihistamines, Classical
- Classical Antihistamines
- Antihistaminics, Classical
- Classical Antihistaminics
- First Generation H1 Antagonists
- Antihistamines, Sedating
- Sedating Antihistamines
|
Below are MeSH descriptors whose meaning is more general than "Histamine H1 Antagonists".
Below are MeSH descriptors whose meaning is more specific than "Histamine H1 Antagonists".
This graph shows the total number of publications written about "Histamine H1 Antagonists" by people in this website by year, and whether "Histamine H1 Antagonists" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 1 | 1 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 2 | 2 | 4 |
| 2008 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
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Below are the most recent publications written about "Histamine H1 Antagonists" by people in Profiles.
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Distinct roles of histamine H1- and H2-receptor signaling pathways in inflammation-associated colonic tumorigenesis. Am J Physiol Gastrointest Liver Physiol. 2019 01 01; 316(1):G205-G216.
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Extracorporeal Cardiopulmonary Resuscitation After Diphenhydramine Ingestion. J Med Toxicol. 2018 09; 14(3):253-256.
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Association of QT-Prolonging Medication Use in CKD with Electrocardiographic Manifestations. Clin J Am Soc Nephrol. 2017 09 07; 12(9):1409-1417.
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Carboplatin Rechallenge After Hypersensitivity Reactions in Pediatric Patients With Low-Grade Glioma. Pediatr Blood Cancer. 2016 Jan; 63(1):21-6.
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Long-term anti-inflammatory and antihistamine medication use and adult glioma risk. Cancer Epidemiol Biomarkers Prev. 2008 May; 17(5):1277-81.
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Comparison of the effectiveness of amitriptyline and gabapentin on chronic neuropathic pain in persons with spinal cord injury. Arch Phys Med Rehabil. 2007 Dec; 88(12):1547-60.
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Suppression of an established immune response by UVA--a critical role for mast cells. Photochem Photobiol. 2007 Sep-Oct; 83(5):1095-100.
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Cashew nut causes more severe reactions than peanut: case-matched comparison in 141 children. Allergy. 2007 Aug; 62(8):913-6.
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Use of anti-inflammatory drugs and lower esophageal sphincter-relaxing drugs and risk of esophageal and gastric cancers. Clin Gastroenterol Hepatol. 2007 Oct; 5(10):1154-1159.e3.
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Effect of topical ophthalmic epinastine and olopatadine on tear volume in mice. Eye Contact Lens. 2006 Dec; 32(6):272-6.