"Uroporphyrinogens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Porphyrinogens which are intermediates in heme biosynthesis. They have four acetic acid and four propionic acid side chains attached to the pyrrole rings. Uroporphyrinogen I and III are formed from polypyrryl methane in the presence of uroporphyrinogen III cosynthetase and uroporphyrin I synthetase, respectively. They can yield uroporphyrins by autooxidation or coproporphyrinogens by decarboxylation.
| Descriptor ID |
D014577
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| MeSH Number(s) |
D03.383.129.578.840.500.700.900 D03.633.400.909.500.700.900 D04.345.783.500.700.900
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Uroporphyrinogens".
Below are MeSH descriptors whose meaning is more specific than "Uroporphyrinogens".
This graph shows the total number of publications written about "Uroporphyrinogens" by people in this website by year, and whether "Uroporphyrinogens" was a major or minor topic of these publications.
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Below are the most recent publications written about "Uroporphyrinogens" by people in Profiles.
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Sampangine inhibits heme biosynthesis in both yeast and human. Eukaryot Cell. 2011 Nov; 10(11):1536-44.
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Uroporphyrinogen decarboxylase from mouse mammary carcinoma and liver of normal and tumor-bearing mouse. Comp Biochem Physiol B. 1992 May; 102(1):87-92.