"Arylsulfotransferase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sulfotransferase that catalyzes the sulfation of a phenol in the presence of 3'-phosphoadenylylsulfate as sulfate donor to yield an aryl sulfate and adenosine 3',5'-bisphosphate. A number of aromatic compounds can act as acceptors; however, organic hydroxylamines are not substrates. Sulfate conjugation by this enzyme is a major pathway for the biotransformation of phenolic and catechol drugs as well as neurotransmitters. EC 2.8.2.1.
| Descriptor ID |
D015239
|
| MeSH Number(s) |
D08.811.913.817.400.300
|
| Concept/Terms |
Arylsulfotransferase- Arylsulfotransferase
- Aryl Sulfotransferase
- Sulfotransferase, Aryl
- Phenolsulfokinase
- Phenol Sulfotransferase
- Sulfotransferase, Phenol
- Sulfokinase
- Phenol Sulfokinase
|
Below are MeSH descriptors whose meaning is more general than "Arylsulfotransferase".
Below are MeSH descriptors whose meaning is more specific than "Arylsulfotransferase".
This graph shows the total number of publications written about "Arylsulfotransferase" by people in this website by year, and whether "Arylsulfotransferase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Arylsulfotransferase" by people in Profiles.
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SULT1A1 and SULT1A2 Associated Extensive Prolapse-Type Inflammatory Polyposis in Crohn's Colitis. Ann Clin Lab Sci. 2021 Nov; 51(6):868-874.
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Expression of sulfotransferase SULT1A1 in cancer cells predicts susceptibility to the novel anticancer agent NSC-743380. Oncotarget. 2015 Jan 01; 6(1):345-54.
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SULT1A3-mediated regiospecific 7-O-sulfation of flavonoids in Caco-2 cells can be explained by the relevant molecular docking studies. Mol Pharm. 2012 Apr 02; 9(4):862-73.
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Role of high-fat diet in regulation of gene expression of drug metabolizing enzymes and transporters. Life Sci. 2011 Jul 04; 89(1-2):57-64.
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Very important pharmacogene summary: sulfotransferase 1A1. Pharmacogenet Genomics. 2009 Jun; 19(6):404-6.
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Interaction of the cytochrome P4501A2, SULT1A1 and NAT gene polymorphisms with smoking and dietary mutagen intake in modification of the risk of pancreatic cancer. Carcinogenesis. 2008 Jun; 29(6):1184-91.
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Activation of aminoflavone (NSC 686288) by a sulfotransferase is required for the antiproliferative effect of the drug and for induction of histone gamma-H2AX. Cancer Res. 2006 Oct 01; 66(19):9656-64.
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Human SULT1A3 pharmacogenetics: gene duplication and functional genomic studies. Biochem Biophys Res Commun. 2004 Sep 03; 321(4):870-8.
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Sulfotransferase 1A1 (SULT1A1) polymorphism and bladder cancer risk: a case-control study. Cancer Lett. 2003 Dec 08; 202(1):61-9.
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Sulfotransferase (SULT) 1A1 polymorphism as a predisposition factor for lung cancer: a case-control analysis. Lung Cancer. 2002 Feb; 35(2):137-42.