"Strychnine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid found in the seeds of STRYCHNOS NUX-VOMICA. It is a competitive antagonist at glycine receptors and thus a convulsant. It has been used as an analeptic, in the treatment of nonketotic hyperglycinemia and sleep apnea, and as a rat poison.
| Descriptor ID |
D013331
|
| MeSH Number(s) |
D03.132.436.681.722 D03.633.100.473.402.681.722
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Strychnine".
Below are MeSH descriptors whose meaning is more specific than "Strychnine".
This graph shows the total number of publications written about "Strychnine" by people in this website by year, and whether "Strychnine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Strychnine" by people in Profiles.
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Light responses and amacrine cell modulation of morphologically-identified retinal ganglion cells in the mouse retina. Vision Res. 2023 04; 205:108187.
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Identification of the hypertension drug niflumic acid as a glycine receptor inhibitor. Sci Rep. 2020 08 19; 10(1):13999.
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The glycine transport inhibitor sarcosine is an inhibitory glycine receptor agonist. Neuropharmacology. 2009 Oct-Nov; 57(5-6):551-5.
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Effects of activation of group III metabotropic glutamate receptors on spinal synaptic transmission in a rat model of neuropathic pain. Neuroscience. 2009 Jan 23; 158(2):875-84.
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HMBC-RELAY: a combined technique for the differentiation of simultaneously detected 2J(C,H) and (n)J(C,H) connectivities. Magn Reson Chem. 2004 Jan; 42(1):55-60.
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Relative contributions of bipolar cell and amacrine cell inputs to light responses of ON, OFF and ON-OFF retinal ganglion cells. Vision Res. 2002 Jan; 42(1):19-27.
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Developmental changes in the neurotransmitter regulation of correlated spontaneous retinal activity. J Neurosci. 2000 Jan 01; 20(1):351-60.
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Reduction in the mechanonociceptive response by intrathecal administration of glycine and related compounds. Neurochem Res. 1996 Oct; 21(10):1221-6.
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Glycine stimulates calcium-independent release of 3H-GABA from isolated retinas of Xenopus laevis. Vis Neurosci. 1990 Apr; 4(4):337-48.
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Uropharmacology: X. Central nervous system stimulants and depressants. Urology. 1979 Apr; 13(4):464-73.