"Hindlimb Suspension" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Technique for limiting use, activity, or movement by immobilizing or restraining animal by suspending from hindlimbs or tails. This immobilization is used to simulate some effects of reduced gravity and study weightlessness physiology.
| Descriptor ID |
D019417
|
| MeSH Number(s) |
E05.472.760.370 E05.977.400 N06.230.150.440.950.400
|
| Concept/Terms |
Hindlimb Suspension- Hindlimb Suspension
- Suspension, Hindlimb
- Hindlimb Unloading
- Unloading, Hindlimb
- Unloadings, Hindlimb
- Hindlimb Elevation
- Elevation, Hindlimb
- Hindlimb Immobilization
- Immobilization, Hindlimb
Skeletal Unloading- Skeletal Unloading
- Skeletal Unloadings
- Unloading, Skeletal
- Unloadings, Skeletal
|
Below are MeSH descriptors whose meaning is more general than "Hindlimb Suspension".
Below are MeSH descriptors whose meaning is more specific than "Hindlimb Suspension".
This graph shows the total number of publications written about "Hindlimb Suspension" by people in this website by year, and whether "Hindlimb Suspension" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 1 | 2 |
| 2009 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 2 | 2 |
| 2020 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
| 2025 | 1 | 0 | 1 |
| 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "Hindlimb Suspension" by people in Profiles.
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A Validated Transcriptomic NMJ Remodeling Score Reveals Synaptic Dysfunction Independent of Muscle Atrophy after Immobilization in a Microgravity Analog. Neuroinformatics. 2026 Jan 24; 24(1):8.
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Hindlimb unloading results in accelerated bone loss compared to aging in select bone compartments of female murine femurs. J Biomech. 2026 Jan; 195:113134.
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A comparison of bone microarchitectural and transcriptomic changes in murine long bones in response to hindlimb unloading and aging. Bone. 2024 02; 179:116973.
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Abaloparatide treatment increases bone formation, bone density and bone strength without increasing bone resorption in a rat model of hindlimb unloading. Bone. 2021 03; 144:115801.
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Long-term simulated microgravity causes cardiac RyR2 phosphorylation and arrhythmias in mice. Int J Cardiol. 2014 Oct 20; 176(3):994-1000.
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Possible role of non-muscle alpha-actinins in muscle cell mechanosensitivity. PLoS One. 2014; 9(4):e96395.
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Combined effects of botulinum toxin injection and hind limb unloading on bone and muscle. Calcif Tissue Int. 2014 Mar; 94(3):327-37.
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Progesterone modulation of alpha5 nAChR subunits influences anxiety-related behavior during estrus cycle. Genes Brain Behav. 2009 Jun; 8(4):398-406.
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Differential skeletal responses of hindlimb unloaded rats on a vitamin D-deficient diet to 1,25-dihydroxyvitamin D3 and its analog, seocalcitol (EB1089). Bone. 2004 Jul; 35(1):134-43.
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Kinetics of rotavirus infection in mice are not altered in a ground-based model of spaceflight. Aviat Space Environ Med. 2004 Mar; 75(3):215-9.