"Gene Deletion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A genetic rearrangement through loss of segments of DNA or RNA, bringing sequences which are normally separated into close proximity. This deletion may be detected using cytogenetic techniques and can also be inferred from the phenotype, indicating a deletion at one specific locus.
| Descriptor ID |
D017353
|
| MeSH Number(s) |
G05.365.590.762.320 G05.558.800.320
|
| Concept/Terms |
Gene Deletion- Gene Deletion
- Deletion, Gene
- Deletions, Gene
- Gene Deletions
|
Below are MeSH descriptors whose meaning is more general than "Gene Deletion".
Below are MeSH descriptors whose meaning is more specific than "Gene Deletion".
This graph shows the total number of publications written about "Gene Deletion" by people in this website by year, and whether "Gene Deletion" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 5 | 10 | 15 |
| 1996 | 3 | 6 | 9 |
| 1997 | 8 | 5 | 13 |
| 1998 | 5 | 10 | 15 |
| 1999 | 3 | 10 | 13 |
| 2000 | 3 | 13 | 16 |
| 2001 | 5 | 7 | 12 |
| 2002 | 2 | 12 | 14 |
| 2003 | 4 | 13 | 17 |
| 2004 | 5 | 16 | 21 |
| 2005 | 4 | 18 | 22 |
| 2006 | 2 | 8 | 10 |
| 2007 | 5 | 16 | 21 |
| 2008 | 5 | 15 | 20 |
| 2009 | 7 | 14 | 21 |
| 2010 | 8 | 15 | 23 |
| 2011 | 8 | 13 | 21 |
| 2012 | 5 | 22 | 27 |
| 2013 | 5 | 20 | 25 |
| 2014 | 6 | 19 | 25 |
| 2015 | 2 | 17 | 19 |
| 2016 | 2 | 15 | 17 |
| 2017 | 3 | 18 | 21 |
| 2018 | 9 | 12 | 21 |
| 2019 | 4 | 9 | 13 |
| 2020 | 1 | 10 | 11 |
| 2021 | 3 | 21 | 24 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "Gene Deletion" by people in Profiles.
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Large-scale CRISPR/Cas9 deletions within the WFDC gene cluster uncover gene functionality and critical roles in mammalian reproduction. Proc Natl Acad Sci U S A. 2024 Dec 17; 121(51):e2413195121.
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Neurodevelopmental Disorder Caused by Deletion of CHASERR, a lncRNA Gene. N Engl J Med. 2024 Oct 24; 391(16):1511-1518.
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Generation of a Wt1 conditional deletion, nuclear red fluorescent protein reporter allele in the mouse. Differentiation. 2024 Jul-Aug; 138:100791.
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Prognostic value of DNA methylation subclassification, aneuploidy, and CDKN2A/B homozygous deletion in predicting clinical outcome of IDH mutant astrocytomas. Neuro Oncol. 2024 06 03; 26(6):1042-1051.
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Genetic Deletion of Galectin-3 Inhibits Pancreatic Cancer Progression and Enhances the Efficacy of Immunotherapy. Gastroenterology. 2024 Jul; 167(2):298-314.
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P2Y2 purinergic receptor gene deletion protects mice from bacterial endotoxin and sepsis-associated liver injury and mortality. Am J Physiol Gastrointest Liver Physiol. 2023 11 01; 325(5):G471-G491.
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Hippo-TAZ signaling is the master regulator of the onset of triple-negative basal-like breast cancers. Proc Natl Acad Sci U S A. 2022 07 19; 119(29):e2123134119.
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Group B Streptococcus CAMP Factor Does Not Contribute to Interactions with the Vaginal Epithelium and Is Dispensable for Vaginal Colonization in Mice. Microbiol Spectr. 2021 12 22; 9(3):e0105821.
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Characterization of the Type I Restriction Modification System Broadly Conserved among Group A Streptococci. mSphere. 2021 12 22; 6(6):e0079921.
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Estrogen Inhibits Epithelial Progesterone Receptor-Dependent Progestin Therapy Efficacy in a Mouse Model of Cervical Cancer. Am J Pathol. 2022 02; 192(2):353-360.