"Gene Deletion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A genetic rearrangement through loss of segments of DNA or RNA, bringing sequences which are normally separated into close proximity. This deletion may be detected using cytogenetic techniques and can also be inferred from the phenotype, indicating a deletion at one specific locus.
| Descriptor ID |
D017353
|
| MeSH Number(s) |
G05.365.590.762.320 G05.558.800.320
|
| Concept/Terms |
Gene Deletion- Gene Deletion
- Deletion, Gene
- Deletions, Gene
- Gene Deletions
|
Below are MeSH descriptors whose meaning is more general than "Gene Deletion".
Below are MeSH descriptors whose meaning is more specific than "Gene Deletion".
This graph shows the total number of publications written about "Gene Deletion" by people in this website by year, and whether "Gene Deletion" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 3 | 6 | 9 |
| 1997 | 7 | 4 | 11 |
| 1998 | 5 | 10 | 15 |
| 1999 | 2 | 8 | 10 |
| 2000 | 3 | 15 | 18 |
| 2001 | 5 | 8 | 13 |
| 2002 | 2 | 12 | 14 |
| 2003 | 4 | 11 | 15 |
| 2004 | 5 | 16 | 21 |
| 2005 | 4 | 19 | 23 |
| 2006 | 2 | 8 | 10 |
| 2007 | 5 | 15 | 20 |
| 2008 | 5 | 14 | 19 |
| 2009 | 6 | 14 | 20 |
| 2010 | 8 | 14 | 22 |
| 2011 | 8 | 13 | 21 |
| 2012 | 5 | 22 | 27 |
| 2013 | 5 | 19 | 24 |
| 2014 | 6 | 18 | 24 |
| 2015 | 2 | 17 | 19 |
| 2016 | 1 | 15 | 16 |
| 2017 | 3 | 21 | 24 |
| 2018 | 9 | 12 | 21 |
| 2019 | 4 | 12 | 16 |
| 2020 | 1 | 10 | 11 |
| 2021 | 3 | 19 | 22 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 2 | 2 |
| 2025 | 1 | 2 | 3 |
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Below are the most recent publications written about "Gene Deletion" by people in Profiles.
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Deletion of fibro-adipogenic progenitors-specific follistatin impairs muscle function and accelerates skeletal muscle atrophy in obese mice. Mol Med. 2025 Nov 21; 31(1):340.
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Folliculin Deletion in the Mouse Kidney Results in Cystogenesis of the Loops of Henle via Aberrant TFEB Activation. Am J Pathol. 2025 Sep; 195(9):1643-1659.
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Deletion Testing of the DEGS1 Gene Should Be Part of the Diagnostic Pipeline for Hypomyelinating Leukodystrophy (HLD18). Hum Mutat. 2025; 2025:3531508.
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Large-scale CRISPR/Cas9 deletions within the WFDC gene cluster uncover gene functionality and critical roles in mammalian reproduction. Proc Natl Acad Sci U S A. 2024 Dec 17; 121(51):e2413195121.
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Neurodevelopmental Disorder Caused by Deletion of CHASERR, a lncRNA Gene. N Engl J Med. 2024 10 24; 391(16):1511-1518.
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P2Y2 purinergic receptor gene deletion protects mice from bacterial endotoxin and sepsis-associated liver injury and mortality. Am J Physiol Gastrointest Liver Physiol. 2023 11 01; 325(5):G471-G491.
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Hippo-TAZ signaling is the master regulator of the onset of triple-negative basal-like breast cancers. Proc Natl Acad Sci U S A. 2022 07 19; 119(29):e2123134119.
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Group B Streptococcus CAMP Factor Does Not Contribute to Interactions with the Vaginal Epithelium and Is Dispensable for Vaginal Colonization in Mice. Microbiol Spectr. 2021 12 22; 9(3):e0105821.
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Estrogen Inhibits Epithelial Progesterone Receptor-Dependent Progestin Therapy Efficacy in a Mouse Model of Cervical Cancer. Am J Pathol. 2022 02; 192(2):353-360.
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Loss of Hepatic Transcription Factor EB Attenuates Alcohol-Associated Liver Carcinogenesis. Am J Pathol. 2022 01; 192(1):87-103.