beta-Transducin Repeat-Containing Proteins
"beta-Transducin Repeat-Containing Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of F-box domain proteins that contain sequences that are homologous to the beta subunit of transducin (BETA-TRANSDUCIN). They play an important role in the protein degradation pathway by becoming components of SKP CULLIN F-BOX PROTEIN LIGASES, which selectively act on a subset of proteins including beta-catenin and IkappaBbeta.
| Descriptor ID |
D044844
|
| MeSH Number(s) |
D12.776.157.169.500
|
| Concept/Terms |
beta-Transducin Repeat-Containing Proteins- beta-Transducin Repeat-Containing Proteins
- Repeat-Containing Proteins, beta-Transducin
- beta Transducin Repeat Containing Proteins
- beta-Transducin Repeat-Containing Protein
- Protein, beta-Transducin Repeat-Containing
- Repeat-Containing Protein, beta-Transducin
- beta Transducin Repeat Containing Protein
- beta-TrCP
- beta TrCP
- betaTrCP
|
Below are MeSH descriptors whose meaning is more general than "beta-Transducin Repeat-Containing Proteins".
Below are MeSH descriptors whose meaning is more specific than "beta-Transducin Repeat-Containing Proteins".
This graph shows the total number of publications written about "beta-Transducin Repeat-Containing Proteins" by people in this website by year, and whether "beta-Transducin Repeat-Containing Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "beta-Transducin Repeat-Containing Proteins" by people in Profiles.
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TFEB degradation is regulated by an IKK/?-TrCP2 phosphorylation-ubiquitination cascade. Nat Commun. 2026 Apr 01; 17(1).
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?-TrCP-dependent degradation of ASK1 suppresses the induction of the apoptotic response by oxidative stress. Biochim Biophys Acta Gen Subj. 2018 10; 1862(10):2271-2280.
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Genetic Variants in WNT2B and BTRC Predict Melanoma Survival. J Invest Dermatol. 2017 08; 137(8):1749-1756.
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Neddylation plays an important role in the regulation of murine and human dendritic cell function. Blood. 2013 Sep 19; 122(12):2062-73.
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FOXO3a-Dependent Mechanism of E1A-Induced Chemosensitization. Cancer Res. 2011 Nov 01; 71(21):6878-87.
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Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase. Cancer Cell. 2010 Aug 09; 18(2):147-59.
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Inhibition of FOXO3 tumor suppressor function by betaTrCP1 through ubiquitin-mediated degradation in a tumor mouse model. PLoS One. 2010 Jul 02; 5(7):e11171.
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Rotavirus NSP1 inhibits NFkappaB activation by inducing proteasome-dependent degradation of beta-TrCP: a novel mechanism of IFN antagonism. PLoS Pathog. 2009 Jan; 5(1):e1000280.
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SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation. Nature. 2008 Mar 20; 452(7185):370-4.
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beta-TrCP binding and processing of NF-kappaB2/p100 involve its phosphorylation at serines 866 and 870. Cell Signal. 2006 Aug; 18(8):1309-17.