beta-Transducin Repeat-Containing Proteins
"beta-Transducin Repeat-Containing Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of F-box domain proteins that contain sequences that are homologous to the beta subunit of transducin (BETA-TRANSDUCIN). They play an important role in the protein degradation pathway by becoming components of SKP CULLIN F-BOX PROTEIN LIGASES, which selectively act on a subset of proteins including beta-catenin and IkappaBbeta.
| Descriptor ID |
D044844
|
| MeSH Number(s) |
D12.776.157.169.500
|
| Concept/Terms |
beta-Transducin Repeat-Containing Proteins- beta-Transducin Repeat-Containing Proteins
- Repeat-Containing Proteins, beta-Transducin
- beta Transducin Repeat Containing Proteins
- beta-Transducin Repeat-Containing Protein
- Protein, beta-Transducin Repeat-Containing
- Repeat-Containing Protein, beta-Transducin
- beta Transducin Repeat Containing Protein
- beta-TrCP
- beta TrCP
- betaTrCP
|
Below are MeSH descriptors whose meaning is more general than "beta-Transducin Repeat-Containing Proteins".
Below are MeSH descriptors whose meaning is more specific than "beta-Transducin Repeat-Containing Proteins".
This graph shows the total number of publications written about "beta-Transducin Repeat-Containing Proteins" by people in this website by year, and whether "beta-Transducin Repeat-Containing Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2004 | 2 | 0 | 2 |
| 2005 | 2 | 1 | 3 |
| 2007 | 1 | 0 | 1 |
| 2008 | 2 | 1 | 3 |
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 2 | 4 |
| 2011 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 0 | 2 | 2 |
| 2017 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "beta-Transducin Repeat-Containing Proteins" by people in Profiles.
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SDCBP promotes pancreatic cancer progression by preventing YAP1 from ?-TrCP-mediated proteasomal degradation. Gut. 2023 09; 72(9):1722-1737.
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Casein kinase 1a decreases ?-catenin levels at adherens junctions to facilitate wound closure in Drosophila larvae. Development. 2019 10 02; 146(20).
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Genetic Variants in WNT2B and BTRC Predict Melanoma Survival. J Invest Dermatol. 2017 08; 137(8):1749-1756.
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Synthetic essentiality of chromatin remodelling factor CHD1 in PTEN-deficient cancer. Nature. 2017 02 23; 542(7642):484-488.
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Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity. Nat Commun. 2016 08 30; 7:12632.
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AKT1 Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer through Phosphorylation-Dependent Twist1 Degradation. Cancer Res. 2016 Mar 15; 76(6):1451-62.
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SCF ?-TRCP targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration. Oncotarget. 2013 Dec; 4(12):2339-53.
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FOXO3a-Dependent Mechanism of E1A-Induced Chemosensitization. Cancer Res. 2011 Nov 01; 71(21):6878-87.
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Dual-color click beetle luciferase heteroprotein fragment complementation assays. Chem Biol. 2010 Sep 24; 17(9):1018-29.
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Phosphorylation by casein kinase I promotes the turnover of the Mdm2 oncoprotein via the SCF(beta-TRCP) ubiquitin ligase. Cancer Cell. 2010 Aug 09; 18(2):147-59.