"Angiopoietin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The first to be discovered member of the angiopoietin family. It may play a role in increasing the sprouting and branching of BLOOD VESSELS. Angiopoietin-1 specifically binds to and stimulates the TIE-2 RECEPTOR. Several isoforms of angiopoietin-1 occur due to ALTERNATIVE SPLICING of its mRNA.
| Descriptor ID |
D042683
|
| MeSH Number(s) |
D12.644.276.100.100.100 D12.776.467.100.100.100 D23.529.100.100.100
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Angiopoietin-1".
Below are MeSH descriptors whose meaning is more specific than "Angiopoietin-1".
This graph shows the total number of publications written about "Angiopoietin-1" by people in this website by year, and whether "Angiopoietin-1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Angiopoietin-1" by people in Profiles.
-
PDGFRa+ Cells in Embryonic Stem Cell Cultures Represent the In?Vitro Equivalent of the Pre-implantation Primitive Endoderm Precursors. Stem Cell Reports. 2017 02 14; 8(2):318-333.
-
Tubular Overexpression of Angiopoietin-1 Attenuates Renal Fibrosis. PLoS One. 2016; 11(7):e0158908.
-
Angiopoietin-1 improves endothelial progenitor cell-dependent neovascularization in diabetic wounds. Surgery. 2015 Sep; 158(3):846-56.
-
Angiopoietin-1 treatment reduces inflammation but does not prevent ventilator-induced lung injury. PLoS One. 2010 Dec 14; 5(12):e15653.
-
COUP-TFII regulates tumor growth and metastasis by modulating tumor angiogenesis. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3687-92.
-
MEKK3 is required for endothelium function but is not essential for tumor growth and angiogenesis. Am J Physiol Cell Physiol. 2007 Oct; 293(4):C1404-11.
-
Continuous delivery of IFN-beta promotes sustained maturation of intratumoral vasculature. Mol Cancer Res. 2007 Jun; 5(6):531-42.
-
Tie2 activation contributes to hemangiogenic regeneration after myelosuppression. Blood. 2005 Jul 15; 106(2):505-13.