"Dystroglycans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Dystrophin-associated proteins that play role in the formation of a transmembrane link between laminin-2 and DYSTROPHIN. Both the alpha and the beta subtypes of dystroglycan originate via POST-TRANSLATIONAL PROTEIN PROCESSING of a single precursor protein.
| Descriptor ID |
D049030
|
| MeSH Number(s) |
D12.776.210.500.410.500 D12.776.220.362.249 D12.776.543.268.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Dystroglycans".
Below are MeSH descriptors whose meaning is more specific than "Dystroglycans".
This graph shows the total number of publications written about "Dystroglycans" by people in this website by year, and whether "Dystroglycans" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 2 | 0 | 2 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Dystroglycans" by people in Profiles.
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N-terminal domain on dystroglycan enables LARGE1 to extend matriglycan on a-dystroglycan and prevents muscular dystrophy. Elife. 2023 02 01; 12.
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POMK regulates dystroglycan function via LARGE1-mediated elongation of matriglycan. Elife. 2020 09 25; 9.
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POGLUT1 biallelic mutations cause myopathy with reduced satellite cells, a-dystroglycan hypoglycosylation and a distinctive radiological pattern. Acta Neuropathol. 2020 03; 139(3):565-582.
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Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability. Nat Commun. 2019 01 08; 10(1):76.
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Dystrophin-glycoprotein complex sequesters Yap to inhibit cardiomyocyte proliferation. Nature. 2017 07 13; 547(7662):227-231.
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Structure of protein O-mannose kinase reveals a unique active site architecture. Elife. 2016 11 23; 5.
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Glucocorticoid Steroid and Alendronate Treatment Alleviates Dystrophic Phenotype with Enhanced Functional Glycosylation of a-Dystroglycan in Mouse Model of Limb-Girdle Muscular Dystrophy with FKRPP448L Mutation. Am J Pathol. 2016 06; 186(6):1635-48.
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Novel cardiovascular findings in association with a POMT2 mutation: three siblings with a-dystroglycanopathy. Eur J Hum Genet. 2014 Apr; 22(4):486-91.
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Increased expression of CD133 and reduced dystroglycan expression are strong predictors of poor outcome in colon cancer patients. J Exp Clin Cancer Res. 2012 Sep 11; 31:71.
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Loss of nuclear p27(kip1) and a-dystroglycan is a frequent event and is a strong predictor of poor outcome in renal cell carcinoma. Cancer Sci. 2010 Sep; 101(9):2080-6.