"Dystroglycans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Dystrophin-associated proteins that play role in the formation of a transmembrane link between laminin-2 and DYSTROPHIN. Both the alpha and the beta subtypes of dystroglycan originate via POST-TRANSLATIONAL PROTEIN PROCESSING of a single precursor protein.
| Descriptor ID |
D049030
|
| MeSH Number(s) |
D12.776.210.500.410.500 D12.776.220.362.249 D12.776.543.268.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Dystroglycans".
Below are MeSH descriptors whose meaning is more specific than "Dystroglycans".
This graph shows the total number of publications written about "Dystroglycans" by people in this website by year, and whether "Dystroglycans" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2007 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 1 | 2 |
| 2013 | 0 | 1 | 1 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Dystroglycans" by people in Profiles.
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POGLUT1 biallelic mutations cause myopathy with reduced satellite cells, a-dystroglycan hypoglycosylation and a distinctive radiological pattern. Acta Neuropathol. 2020 03; 139(3):565-582.
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The dystroglycan receptor maintains glioma stem cells in the vascular niche. Acta Neuropathol. 2019 12; 138(6):1033-1052.
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Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability. Nat Commun. 2019 01 08; 10(1):76.
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Diagnosis and etiology of congenital muscular dystrophy: We are halfway there. Ann Neurol. 2016 07; 80(1):101-11.
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Novel cardiovascular findings in association with a POMT2 mutation: three siblings with a-dystroglycanopathy. Eur J Hum Genet. 2014 Apr; 22(4):486-91.
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Mutations in GDP-mannose pyrophosphorylase B cause congenital and limb-girdle muscular dystrophies associated with hypoglycosylation of a-dystroglycan. Am J Hum Genet. 2013 Jul 11; 93(1):29-41.
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Increased expression of CD133 and reduced dystroglycan expression are strong predictors of poor outcome in colon cancer patients. J Exp Clin Cancer Res. 2012 Sep 11; 31:71.
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Interstitial guidance of cancer invasion. J Pathol. 2012 Jan; 226(2):185-99.
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Loss of nuclear p27(kip1) and a-dystroglycan is a frequent event and is a strong predictor of poor outcome in renal cell carcinoma. Cancer Sci. 2010 Sep; 101(9):2080-6.
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Expression of dystroglycan correlates with tumor grade and predicts survival in renal cell carcinoma. Cancer Biol Ther. 2007 Dec; 6(12):1840-6.