"Tyrosine Transaminase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the conversion of L-TYROSINE and 2-oxoglutarate to 4-hydroxyphenylpyruvate and L-GLUTAMATE. It is a pyridoxal-phosphate protein. L-PHENYLALANINE is hydroxylated to L-tyrosine. The mitochondrial enzyme may be identical with ASPARTATE AMINOTRANSFERASES (EC 2.6.1.1.). Deficiency of this enzyme may cause type II Tyrosinemia (see TYROSINEMIAS). EC 2.6.1.5.
| Descriptor ID |
D014444
|
| MeSH Number(s) |
D08.811.913.477.700.900
|
| Concept/Terms |
Tyrosine Transaminase- Tyrosine Transaminase
- Transaminase, Tyrosine
- Tyrosine Aminotransferase
- Aminotransferase, Tyrosine
|
Below are MeSH descriptors whose meaning is more general than "Tyrosine Transaminase".
Below are MeSH descriptors whose meaning is more specific than "Tyrosine Transaminase".
This graph shows the total number of publications written about "Tyrosine Transaminase" by people in this website by year, and whether "Tyrosine Transaminase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tyrosine Transaminase" by people in Profiles.
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Targeting glioma-initiating cells via the tyrosine metabolic pathway. J Neurosurg. 2021 03 01; 134(3):721-732.
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Hepatic SRC-1 activity orchestrates transcriptional circuitries of amino acid pathways with potential relevance for human metabolic pathogenesis. Mol Endocrinol. 2014 Oct; 28(10):1707-18.
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Lack of C/EBP alpha gene expression results in increased DNA synthesis and an increased frequency of immortalization of freshly isolated mice [correction of rat] hepatocytes. Hepatology. 1998 Feb; 27(2):392-401.
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X-linked glycerol kinase deficiency in the mouse leads to growth retardation, altered fat metabolism, autonomous glucocorticoid secretion and neonatal death. Hum Mol Genet. 1997 Oct; 6(11):1803-9.
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Cooperative binding of steroid hormone receptors contributes to transcriptional synergism at target enhancer elements. Cell. 1989 May 05; 57(3):443-8.
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A tyrosine aminotransferase glucocorticoid response element also mediates androgen enhancement of gene expression. Endocrinology. 1989 Feb; 124(2):1091-3.
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A steroid response element can function in the absence of a distal promoter. Mol Endocrinol. 1988 Dec; 2(12):1286-93.
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The expressions of oncogenes and liver-specific genes in Morris hepatomas. Biochem Biophys Res Commun. 1987 Mar 13; 143(2):624-9.
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Chromosomal assignment and trans regulation of the tyrosine aminotransferase structural gene in hepatoma hybrid cells. Mol Cell Biol. 1985 Sep; 5(9):2491-4.
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A genetic analysis of extinction: trans-dominant loci regulate expression of liver-specific traits in hepatoma hybrid cells. Cell. 1984 Sep; 38(2):523-34.