Telomeric Repeat Binding Protein 1
"Telomeric Repeat Binding Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed telomere-binding protein that is present at TELOMERES throughout the CELL CYCLE. It is a suppressor of telomere elongation and may be involved in stabilization of telomere length. It is structurally different from TELOMERIC REPEAT BINDING PROTEIN 2 in that it contains acidic N-terminal amino acid residues.
| Descriptor ID |
D035321
|
| MeSH Number(s) |
D12.776.260.735.750 D12.776.660.235.700.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Telomeric Repeat Binding Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Telomeric Repeat Binding Protein 1".
This graph shows the total number of publications written about "Telomeric Repeat Binding Protein 1" by people in this website by year, and whether "Telomeric Repeat Binding Protein 1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Telomeric Repeat Binding Protein 1" by people in Profiles.
-
Rho GDP-dissociation inhibitor a is a potential prognostic biomarker and controls telomere regulation in colorectal cancer. Cancer Sci. 2017 Jul; 108(7):1293-1302.
-
Single-strand DNA-binding protein SSB1 facilitates TERT recruitment to telomeres and maintains telomere G-overhangs. Cancer Res. 2015 Mar 01; 75(5):858-69.
-
Telomerase suppresses formation of ALT-associated single-stranded telomeric C-circles. Mol Cancer Res. 2013 Jun; 11(6):557-67.
-
Three novel truncating TINF2 mutations causing severe dyskeratosis congenita in early childhood. Clin Genet. 2012 May; 81(5):470-8.
-
Gcn5 and SAGA regulate shelterin protein turnover and telomere maintenance. Mol Cell. 2009 Aug 14; 35(3):352-64.
-
c-Myc interacts with TRF1/PIN2 and regulates telomere length. Biochem Biophys Res Commun. 2007 Nov 03; 362(4):842-7.
-
Expression of telomere-associated genes as prognostic markers for overall survival in patients with non-small cell lung cancer. Clin Cancer Res. 2006 Oct 01; 12(19):5720-5.
-
A critical role for TPP1 and TIN2 interaction in high-order telomeric complex assembly. Proc Natl Acad Sci U S A. 2006 Aug 08; 103(32):11874-9.
-
Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins. J Biol Chem. 2004 Dec 03; 279(49):51338-42.
-
Molecular cloning and chromosomal localization of Chinese hamster telomeric protein chTRF1. Its potential role in chromosomal instability. Oncogene. 1998 Oct 22; 17(16):2137-42.