"Organ of Corti" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The spiral EPITHELIUM containing sensory AUDITORY HAIR CELLS and supporting cells in the cochlea. Organ of Corti, situated on the BASILAR MEMBRANE and overlaid by a gelatinous TECTORIAL MEMBRANE, converts sound-induced mechanical waves to neural impulses to the brain.
| Descriptor ID |
D009925
|
| MeSH Number(s) |
A09.246.631.246.577
|
| Concept/Terms |
Organ of Corti- Organ of Corti
- Corti Organ
- Spiral Organ
- Organ, Spiral
- Organs, Spiral
- Spiral Organs
- Corti's Organ
- Cortis Organ
- Organ, Corti's
|
Below are MeSH descriptors whose meaning is more general than "Organ of Corti".
Below are MeSH descriptors whose meaning is more specific than "Organ of Corti".
This graph shows the total number of publications written about "Organ of Corti" by people in this website by year, and whether "Organ of Corti" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 2 | 1 | 3 |
| 2020 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Organ of Corti" by people in Profiles.
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Lrrn1 Regulates Medial Boundary Formation in the Developing Mouse Organ of Corti. J Neurosci. 2023 07 19; 43(29):5305-5318.
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Organ of Corti size is governed by Yap/Tead-mediated progenitor self-renewal. Proc Natl Acad Sci U S A. 2020 06 16; 117(24):13552-13561.
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Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates. Elife. 2016 12 14; 5.
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Transcriptomic Analysis of Mouse Cochlear Supporting Cell Maturation Reveals Large-Scale Changes in Notch Responsiveness Prior to the Onset of Hearing. PLoS One. 2016; 11(12):e0167286.
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Lineage tracing of Sox2-expressing progenitor cells in the mouse inner ear reveals a broad contribution to non-sensory tissues and insights into the origin of the organ of Corti. Dev Biol. 2016 06 01; 414(1):72-84.
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A Novel Locus Harbouring a Functional CD164 Nonsense Mutation Identified in a Large Danish Family with Nonsyndromic Hearing Impairment. PLoS Genet. 2015 Jul; 11(7):e1005386.
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Conserved role of Sonic Hedgehog in tonotopic organization of the avian basilar papilla and mammalian cochlea. Proc Natl Acad Sci U S A. 2015 Mar 24; 112(12):3746-51.
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Conditional deletion of Atoh1 reveals distinct critical periods for survival and function of hair cells in the organ of Corti. J Neurosci. 2013 Jun 12; 33(24):10110-22.
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Reduced phosphatidylinositol 4,5-bisphosphate synthesis impairs inner ear Ca2+ signaling and high-frequency hearing acquisition. Proc Natl Acad Sci U S A. 2012 Aug 28; 109(35):14013-8.
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Jxc1/Sobp, encoding a nuclear zinc finger protein, is critical for cochlear growth, cell fate, and patterning of the organ of corti. J Neurosci. 2008 Jun 25; 28(26):6633-41.