"Ofloxacin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
| Descriptor ID |
D015242
|
| MeSH Number(s) |
D03.633.100.810.835.322.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ofloxacin".
Below are MeSH descriptors whose meaning is more specific than "Ofloxacin".
This graph shows the total number of publications written about "Ofloxacin" by people in this website by year, and whether "Ofloxacin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2003 | 0 | 3 | 3 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 2 | 3 |
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 1 | 3 |
| 2011 | 0 | 2 | 2 |
| 2012 | 2 | 2 | 4 |
| 2013 | 0 | 2 | 2 |
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Below are the most recent publications written about "Ofloxacin" by people in Profiles.
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Readmissions for warfarin-related bleeding in pediatric patients after hospital discharge. Pediatr Blood Cancer. 2013 Sep; 60(9):1503-6.
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Effect of fluoroquinolone resistance on 14-day levofloxacin triple and triple plus bismuth quadruple therapy. Helicobacter. 2013 Oct; 18(5):373-7.
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Which Therapy for Helicobacter pylori Infection? Gastroenterology. 2012 Jul; 143(1):10-2.
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Guide regarding choice of second-line therapy to obtain a high cumulative cure rate. Helicobacter. 2012 Aug; 17(4):243-5.
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Legionella micdadei prosthetic valve endocarditis complicated by brain abscess: case report and review of the literature. Scand J Infect Dis. 2012 Jun; 44(6):414-8.
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Temporal interplay between efflux pumps and target mutations in development of antibiotic resistance in Escherichia coli. Antimicrob Agents Chemother. 2012 Apr; 56(4):1680-5.
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Incidence of moxifloxacin resistance in clinical Mycobacterium tuberculosis isolates in Houston, Texas. J Clin Microbiol. 2011 Aug; 49(8):2942-5.
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Modelling biphasic killing of fluoroquinolones: guiding optimal dosing regimen design. J Antimicrob Chemother. 2011 May; 66(5):1079-86.
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Impact of recA on levofloxacin exposure-related resistance development. Antimicrob Agents Chemother. 2010 Oct; 54(10):4262-8.
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Quantitative assessment of combination antimicrobial therapy against multidrug-resistant bacteria in a murine pneumonia model. J Infect Dis. 2010 Mar 15; 201(6):889-97.