"Cyclophilin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 17-KDa cytoplasmic PEPTIDYLPROLYL ISOMERASE involved in immunoregulation. It is a member of the cyclophilin family of proteins that binds to CYCLOSPORINE.
Descriptor ID |
D021984
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MeSH Number(s) |
D08.811.399.325.500.400.300.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cyclophilin A".
Below are MeSH descriptors whose meaning is more specific than "Cyclophilin A".
This graph shows the total number of publications written about "Cyclophilin A" by people in this website by year, and whether "Cyclophilin A" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 |
2005 | 2 | 0 | 2 |
2008 | 1 | 0 | 1 |
2009 | 2 | 0 | 2 |
2010 | 1 | 0 | 1 |
2011 | 1 | 0 | 1 |
2014 | 1 | 0 | 1 |
2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cyclophilin A" by people in Profiles.
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Chemical remodeling of a cellular chaperone to target the active state of mutant KRAS. Science. 2023 08 18; 381(6659):794-799.
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Secreted cyclophilin A mediates G1/S phase transition of cholangiocarcinoma cells via CD147/ERK1/2 pathway. Tumour Biol. 2015 Feb; 36(2):849-59.
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Cyclophilin A enhances cell proliferation and tumor growth of liver fluke-associated cholangiocarcinoma. Mol Cancer. 2011 Aug 26; 10:102.
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Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E-deficient mice. J Exp Med. 2011 Jan 17; 208(1):53-66.
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Cyclophilin A: potential functions and therapeutic target for human cancer. Med Sci Monit. 2009 Nov; 15(11):RA221-32.
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Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II-induced aortic aneurysms. Nat Med. 2009 Jun; 15(6):649-56.
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Cyclophilin A mediates vascular remodeling by promoting inflammation and vascular smooth muscle cell proliferation. Circulation. 2008 Jun 17; 117(24):3088-98.
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Effects of cyclophilin A on myeloblastic cell line KG-1 derived dendritic like cells (DLC) through p38 MAP kinase activation. J Surg Res. 2005 Jul 01; 127(1):29-38.
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Effects of cyclophilin A on cell proliferation and gene expressions in human vascular smooth muscle cells and endothelial cells. J Surg Res. 2005 Feb; 123(2):312-9.
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Determination of cyclin D1 and CD20 mRNA levels by real-time quantitative RT-PCR from archival tissue sections of mantle cell lymphoma and other non-Hodgkin's lymphomas. J Mol Diagn. 2002 Nov; 4(4):201-8.