"Desmin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An intermediate filament protein found predominantly in smooth, skeletal, and cardiac muscle cells. Localized at the Z line. MW 50,000 to 55,000 is species dependent.
| Descriptor ID |
D003893
|
| MeSH Number(s) |
D05.750.078.593.200 D12.776.220.475.200
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Desmin".
Below are MeSH descriptors whose meaning is more specific than "Desmin".
This graph shows the total number of publications written about "Desmin" by people in this website by year, and whether "Desmin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 3 | 3 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 5 | 5 |
| 1999 | 1 | 4 | 5 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 3 | 3 |
| 2004 | 1 | 1 | 2 |
| 2005 | 1 | 2 | 3 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 3 | 3 |
| 2010 | 1 | 2 | 3 |
| 2011 | 2 | 1 | 3 |
| 2012 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Desmin" by people in Profiles.
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Desmin deficiency is not sufficient to prevent corneal fibrosis. Exp Eye Res. 2019 03; 180:155-163.
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Amelioration of desmin network defects by aB-crystallin overexpression confers cardioprotection in a mouse model of dilated cardiomyopathy caused by LMNA gene mutation. J Mol Cell Cardiol. 2018 12; 125:73-86.
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Type III Intermediate Filaments Desmin, Glial Fibrillary Acidic Protein (GFAP), Vimentin, and Peripherin. Cold Spring Harb Perspect Biol. 2017 Dec 01; 9(12).
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Opposite effects of catalase and MnSOD ectopic expression on stress induced defects and mortality in the desmin deficient cardiomyopathy model. Free Radic Biol Med. 2017 09; 110:206-218.
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Nebulette is a powerful cytolinker organizing desmin and actin in mouse hearts. Mol Biol Cell. 2016 12 01; 27(24):3869-3882.
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Desmin and aB-crystallin interplay in the maintenance of mitochondrial homeostasis and cardiomyocyte survival. J Cell Sci. 2016 10 15; 129(20):3705-3720.
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Strategies to Study Desmin in Cardiac Muscle and Culture Systems. Methods Enzymol. 2016; 568:427-59.
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Tumor necrosis factor-a confers cardioprotection through ectopic expression of keratins K8 and K18. Nat Med. 2015 Sep; 21(9):1076-84.
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Complement system modulation as a target for treatment of arrhythmogenic cardiomyopathy. Basic Res Cardiol. 2015 May; 110(3):27.
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Desmin related disease: a matter of cell survival failure. Curr Opin Cell Biol. 2015 Feb; 32:113-20.