"Muscular Atrophy, Spinal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Descriptor ID |
D009134
|
| MeSH Number(s) |
C10.228.854.468 C10.574.562.500 C10.668.467.500
|
| Concept/Terms |
Muscular Atrophy, Spinal- Muscular Atrophy, Spinal
- Atrophy, Spinal Muscular
- Spinal Amyotrophy
- Amyotrophies, Spinal
- Amyotrophy, Spinal
- Spinal Amyotrophies
- Spinal Muscular Atrophy
Hereditary Motor Neuronopathy- Hereditary Motor Neuronopathy
- Hereditary Motor Neuronopathies
- Motor Neuronopathies, Hereditary
- Motor Neuronopathy, Hereditary
- Neuronopathies, Hereditary Motor
- Neuronopathy, Hereditary Motor
Scapuloperoneal Form of Spinal Muscular Atrophy- Scapuloperoneal Form of Spinal Muscular Atrophy
- Spinal Muscular Atrophy, Scapuloperoneal Form
- Spinal Muscular Atrophy, Scapuloperoneal
- Amyotrophy, Neurogenic Scapuloperoneal, New England Type
- Scapuloperoneal Spinal Muscular Atrophy
Progressive Muscular Atrophy- Progressive Muscular Atrophy
- Atrophies, Progressive Muscular
- Atrophy, Progressive Muscular
- Muscular Atrophies, Progressive
- Muscular Atrophy, Progressive
- Progressive Muscular Atrophies
- Progressive Myelopathic Muscular Atrophy
- Myelopathic Muscular Atrophy, Progressive
Bulbospinal Neuronopathy- Bulbospinal Neuronopathy
- Bulbospinal Neuronopathies
- Neuronopathies, Bulbospinal
- Neuronopathy, Bulbospinal
Myelopathic Muscular Atrophy- Myelopathic Muscular Atrophy
- Atrophy, Myelopathic Muscular
- Muscular Atrophy, Myelopathic
- Adult-Onset Spinal Muscular Atrophy
- Adult Onset Spinal Muscular Atrophy
- Muscular Atrophy, Adult Spinal
- Adult Spinal Muscular Atrophy
|
Below are MeSH descriptors whose meaning is more general than "Muscular Atrophy, Spinal".
Below are MeSH descriptors whose meaning is more specific than "Muscular Atrophy, Spinal".
This graph shows the total number of publications written about "Muscular Atrophy, Spinal" by people in this website by year, and whether "Muscular Atrophy, Spinal" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 2 | 0 | 2 |
| 1997 | 1 | 1 | 2 |
| 1998 | 2 | 0 | 2 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2003 | 0 | 2 | 2 |
| 2009 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2017 | 2 | 1 | 3 |
| 2018 | 2 | 0 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 2 | 3 |
| 2022 | 1 | 0 | 1 |
| 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "Muscular Atrophy, Spinal" by people in Profiles.
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Risdiplam treatment following onasemnogene abeparvovec in individuals with spinal muscular atrophy: a multicenter case series. BMC Neurol. 2025 Jul 07; 25(1):283.
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Prenatal genetic counseling challenges with indeterminate SMA results. J Genet Couns. 2025 Apr; 34(2):e2017.
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Novel gene-intergenic fusion involving ubiquitin E3 ligase UBE3C causes distal hereditary motor neuropathy. Brain. 2023 03 01; 146(3):880-897.
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A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II. Nat Commun. 2022 09 16; 13(1):5453.
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Novel use of nusinersen as a therapeutic bridge to onasemnogene abeparvovec-xioi in a premature neonate with type 1 spinal muscular atrophy. Muscle Nerve. 2022 08; 66(2):E8-E10.
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ASAH1 pathogenic variants associated with acid ceramidase deficiency: Farber disease and spinal muscular atrophy with progressive myoclonic epilepsy. Hum Mutat. 2020 09; 41(9):1469-1487.
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GARS-related disease in infantile spinal muscular atrophy: Implications for diagnosis and treatment. Am J Med Genet A. 2020 05; 182(5):1167-1176.
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Impact of scoliosis surgery on pulmonary function in patients with muscular dystrophies and spinal muscular atrophy. Pediatr Pulmonol. 2020 04; 55(4):1037-1042.
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Modelling the pathogenesis of X-linked distal hereditary motor neuropathy using patient-derived iPSCs. Dis Model Mech. 2020 01 13; 13(2).
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Arthrogryposis. Am J Obstet Gynecol. 2019 12; 221(6):B7-B9.