Group X Phospholipases A2
"Group X Phospholipases A2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A secreted phospholipase A2 subtype that contains a interfacial-binding region with specificity for PHOSPHATIDYLCHOLINE. This enzyme group may play a role in eliciting ARACHIDONIC ACID release from intact cellular membranes and from LOW DENSITY LIPOPROTEINS. Members of this group bind specifically to PHOSPHOLIPASE A2 RECEPTORS.
| Descriptor ID |
D054509
|
| MeSH Number(s) |
D08.811.277.352.100.680.750.937.750.887
|
| Concept/Terms |
Group X Phospholipases A2- Group X Phospholipases A2
- Group X Secretory Phospholipase A2
- sPLA2-X
- Phospholipase A2, Group X
- Phospholipases A2, Group X
- sPLA(2)-X
- Group X Secretory Phospholipase A(2)
- GX sPLA(2)
|
Below are MeSH descriptors whose meaning is more general than "Group X Phospholipases A2".
Below are MeSH descriptors whose meaning is more specific than "Group X Phospholipases A2".
This graph shows the total number of publications written about "Group X Phospholipases A2" by people in this website by year, and whether "Group X Phospholipases A2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Group X Phospholipases A2" by people in Profiles.
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Phospholipase PLA2G6, a Parkinsonism-Associated Gene, Affects Vps26 and Vps35, Retromer Function, and Ceramide Levels, Similar to a-Synuclein Gain. Cell Metab. 2018 10 02; 28(4):605-618.e6.
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Group X secretory phospholipase A2 negatively regulates ABCA1 and ABCG1 expression and cholesterol efflux in macrophages. Arterioscler Thromb Vasc Biol. 2010 Oct; 30(10):2014-21.
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Group X secretory phospholipase A(2) augments angiotensin II-induced inflammatory responses and abdominal aortic aneurysm formation in apoE-deficient mice. Atherosclerosis. 2011 Jan; 214(1):58-64.