Group V Phospholipases A2
"Group V Phospholipases A2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subcategory of secreted phospholipases A2 that contains both a negatively charged carboxy-terminal segment and interfacial-binding region specific for PHOSPHATIDYL CHOLINE-containing membranes. This enzyme group may play a role in the release of ARACHIDONIC ACID from phospholipid membranes.
| Descriptor ID |
D054505
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| MeSH Number(s) |
D08.811.277.352.100.680.750.937.750.775
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Group V Phospholipases A2".
Below are MeSH descriptors whose meaning is more specific than "Group V Phospholipases A2".
This graph shows the total number of publications written about "Group V Phospholipases A2" by people in this website by year, and whether "Group V Phospholipases A2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Group V Phospholipases A2" by people in Profiles.
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Group V secretory phospholipase A2 enhances the progression of angiotensin II-induced abdominal aortic aneurysms but confers protection against angiotensin II-induced cardiac fibrosis in apoE-deficient mice. Am J Pathol. 2012 Sep; 181(3):1088-98.
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The capacity of group V sPLA2 to increase atherogenicity of ApoE-/- and LDLR-/- mouse LDL in vitro predicts its atherogenic role in vivo. Arterioscler Thromb Vasc Biol. 2009 Apr; 29(4):532-8.
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Group v secretory phospholipase A2 promotes atherosclerosis: evidence from genetically altered mice. Arterioscler Thromb Vasc Biol. 2007 Mar; 27(3):600-6.