"Intrinsic Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycoprotein secreted by the cells of the GASTRIC GLANDS that is required for the absorption of VITAMIN B 12 (cyanocobalamin). Deficiency of intrinsic factor leads to VITAMIN B 12 DEFICIENCY and ANEMIA, PERNICIOUS.
| Descriptor ID |
D007437
|
| MeSH Number(s) |
D12.776.395.560.494
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Intrinsic Factor".
Below are MeSH descriptors whose meaning is more specific than "Intrinsic Factor".
This graph shows the total number of publications written about "Intrinsic Factor" by people in this website by year, and whether "Intrinsic Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Intrinsic Factor" by people in Profiles.
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Targeted Apoptosis of Parietal Cells Is Insufficient to Induce Metaplasia in Stomach. Gastroenterology. 2017 03; 152(4):762-766.e7.
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A molecular signature of gastric metaplasia arising in response to acute parietal cell loss. Gastroenterology. 2008 Feb; 134(2):511-22.
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Cubilin P1297L mutation associated with hereditary megaloblastic anemia 1 causes impaired recognition of intrinsic factor-vitamin B(12) by cubilin. Blood. 2000 Jul 15; 96(2):405-9.