"Gigantism" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The condition of accelerated and excessive GROWTH in children or adolescents who are exposed to excess HUMAN GROWTH HORMONE before the closure of EPIPHYSES. It is usually caused by somatotroph hyperplasia or a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. These patients are of abnormally tall stature, more than 3 standard deviations above normal mean height for age.
| Descriptor ID |
D005877
|
| MeSH Number(s) |
C05.116.099.492 C05.116.132.479 C19.700.355.528
|
| Concept/Terms |
Gigantism- Gigantism
- Pituitary Gigantism
- Gigantism, Pituitary
|
Below are MeSH descriptors whose meaning is more general than "Gigantism".
Below are MeSH descriptors whose meaning is more specific than "Gigantism".
This graph shows the total number of publications written about "Gigantism" by people in this website by year, and whether "Gigantism" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 2 | 0 | 2 |
| 2016 | 2 | 0 | 2 |
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Below are the most recent publications written about "Gigantism" by people in Profiles.
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Germline or somatic GPR101 duplication leads to X-linked acrogigantism: a clinico-pathological and genetic study. Acta Neuropathol Commun. 2016 06 01; 4(1):56.
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Somatic mosaicism underlies X-linked acrogigantism syndrome in sporadic male subjects. Endocr Relat Cancer. 2016 04; 23(4):221-33.
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Aggressive tumor growth and clinical evolution in a patient with X-linked acro-gigantism syndrome. Endocrine. 2016 Feb; 51(2):236-44.
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X-linked acrogigantism syndrome: clinical profile and therapeutic responses. Endocr Relat Cancer. 2015 Jun; 22(3):353-67.
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Gigantism and acromegaly due to Xq26 microduplications and GPR101 mutation. N Engl J Med. 2014 Dec 18; 371(25):2363-74.
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A patient with a unique frameshift mutation in GPC3, causing Simpson-Golabi-Behmel syndrome, presenting with craniosynostosis, penoscrotal hypospadias, and a large prostatic utricle. Am J Med Genet A. 2013 Dec; 161A(12):3121-5.
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Low factor XII level in an individual with Sotos syndrome. Pediatr Blood Cancer. 2005 Feb; 44(2):187-9.
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Unilateral glaucoma in Sotos syndrome (cerebral gigantism). Am J Ophthalmol. 2000 Dec; 130(6):851-3.
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Images in clinical medicine. Pituitary gigantism. N Engl J Med. 1999 Feb 18; 340(7):524.
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Macrodystrophia lipomatosa: radiographic observations. Br J Radiol. 1992 Sep; 65(777):769-73.