HSP27 Heat-Shock Proteins
"HSP27 Heat-Shock Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subfamily of small heat-shock proteins that function as molecular chaperones that aid in refolding of non-native proteins. They play a protective role that increases cellular survival during times of stress.
| Descriptor ID |
D055551
|
| MeSH Number(s) |
D12.776.580.216.270.625
|
| Concept/Terms |
HSP27 Heat-Shock Proteins- HSP27 Heat-Shock Proteins
- HSP27 Heat Shock Proteins
- Heat-Shock Proteins, HSP27
- HSP27 Protein
- HSP27 Proteins
- Heat Shock Protein beta-1
- Heat Shock Protein beta 1
- Heat-Shock Protein 27
- Heat Shock Protein 27
- Protein 27, Heat-Shock
- Heat-Shock Proteins 27
- Heat Shock Proteins 27
|
Below are MeSH descriptors whose meaning is more general than "HSP27 Heat-Shock Proteins".
Below are MeSH descriptors whose meaning is more specific than "HSP27 Heat-Shock Proteins".
This graph shows the total number of publications written about "HSP27 Heat-Shock Proteins" by people in this website by year, and whether "HSP27 Heat-Shock Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 2 | 2 |
| 2005 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 2 | 0 | 2 |
| 2012 | 2 | 1 | 3 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 1 | 2 |
| 2018 | 3 | 0 | 3 |
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Below are the most recent publications written about "HSP27 Heat-Shock Proteins" by people in Profiles.
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Microstructural changes in the brain mediate the association of AK4, IGFBP5, HSPB2, and ITPK1 with cognitive decline. Neurobiol Aging. 2019 12; 84:17-25.
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Brain IGFBP-5 modifies the relation of depressive symptoms to decline in cognition in older persons. J Affect Disord. 2019 05 01; 250:313-318.
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Targeted brain proteomics uncover multiple pathways to Alzheimer's dementia. Ann Neurol. 2018 07; 84(1):78-88.
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HSP27 is a partner of JAK2-STAT5 and a potential therapeutic target in myelofibrosis. Nat Commun. 2018 04 12; 9(1):1431.
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Analysis of HSP27 and the Autophagy Marker LC3B+ Puncta Following Preoperative Chemotherapy Identifies High-Risk Osteosarcoma Patients. Mol Cancer Ther. 2018 06; 17(6):1315-1323.
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Noxa/HSP27 complex delays degradation of ubiquitylated IkBa in airway epithelial cells to reduce pulmonary inflammation. Mucosal Immunol. 2018 05; 11(3):741-751.
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NSC-87877 inhibits DUSP26 function in neuroblastoma resulting in p53-mediated apoptosis. Cell Death Dis. 2015 Aug 06; 6:e1841.
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High-mobility group box 1-mediated heat shock protein beta 1 expression attenuates mitochondrial dysfunction and apoptosis. J Mol Cell Cardiol. 2015 May; 82:1-12.
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Functional promoter variant rs2868371 of HSPB1 is associated with risk of radiation pneumonitis after chemoradiation for non-small cell lung cancer. Int J Radiat Oncol Biol Phys. 2013 Apr 01; 85(5):1332-9.
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Survival of cancer stem cells under hypoxia and serum depletion via decrease in PP2A activity and activation of p38-MAPKAPK2-Hsp27. PLoS One. 2012; 7(11):e49605.