"Pirenzepine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antimuscarinic agent that inhibits gastric secretion at lower doses than are required to affect gastrointestinal motility, salivary, central nervous system, cardiovascular, ocular, and urinary function. It promotes the healing of duodenal ulcers and due to its cytoprotective action is beneficial in the prevention of duodenal ulcer recurrence. It also potentiates the effect of other antiulcer agents such as CIMETIDINE and RANITIDINE. It is generally well tolerated by patients.
| Descriptor ID |
D010890
|
| MeSH Number(s) |
D03.633.100.079.080.070.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Pirenzepine".
Below are MeSH descriptors whose meaning is more specific than "Pirenzepine".
This graph shows the total number of publications written about "Pirenzepine" by people in this website by year, and whether "Pirenzepine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 3 | 0 | 3 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pirenzepine" by people in Profiles.
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Muscarinic receptor subtypes differentially control synaptic input and excitability of cerebellum-projecting medial vestibular nucleus neurons. J Neurochem. 2016 Apr; 137(2):226-39.
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Up-regulation of spinal muscarinic receptors and increased antinociceptive effect of intrathecal muscarine in diabetic rats. J Pharmacol Exp Ther. 2003 Nov; 307(2):676-81.
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Olanzapine as an antiemetic in refractory nausea and vomiting in advanced cancer. J Pain Symptom Manage. 2003 Jun; 25(6):578-82.
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Divalproex sodium versus olanzapine in the treatment of acute mania in bipolar disorder: health-related quality of life and medical cost outcomes. J Clin Psychiatry. 2003 Mar; 64(3):288-94.
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A comparison of the efficacy, safety, and tolerability of divalproex sodium and olanzapine in the treatment of bipolar disorder. J Clin Psychiatry. 2002 Dec; 63(12):1148-55.
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Tolerability and effectiveness of atypical antipsychotics in male geriatric inpatients. Int J Geriatr Psychiatry. 2001 Feb; 16(2):223-7.
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Olanzapine in Tourette's disorder. J Am Acad Child Adolesc Psychiatry. 2000 Feb; 39(2):139.