"Flumazenil" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent benzodiazepine receptor antagonist. Since it reverses the sedative and other actions of benzodiazepines, it has been suggested as an antidote to benzodiazepine overdoses.
| Descriptor ID |
D005442
|
| MeSH Number(s) |
D03.633.100.079.080.070.305
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Flumazenil".
Below are MeSH descriptors whose meaning is more specific than "Flumazenil".
This graph shows the total number of publications written about "Flumazenil" by people in this website by year, and whether "Flumazenil" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 2 | 2 |
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Below are the most recent publications written about "Flumazenil" by people in Profiles.
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Neurobiological mechanisms of antiallodynic effect of transcranial direct current stimulation (tDCS) in a mice model of neuropathic pain. Brain Res. 2018 03 01; 1682:14-23.
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Phenotype of GABA-transaminase deficiency. Neurology. 2017 May 16; 88(20):1919-1924.
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In vivo measurement of GABA transmission in healthy subjects and schizophrenia patients. Am J Psychiatry. 2015 Nov 01; 172(11):1148-59.
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[11C]flumazenil binding is increased in a dose-dependent manner with tiagabine-induced elevations in GABA levels. PLoS One. 2012; 7(2):e32443.
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No evidence of altered in vivo benzodiazepine receptor binding in schizophrenia. Neuropsychopharmacology. 1999 Jun; 20(6):650-61.
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The effects of the benzodiazepine antagonist Ro 15-1788 on psychophysiological performance and subjective measures in normal subjects. Psychopharmacology (Berl). 1986; 89(4):395-403.
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Relationship of the effects of the benzodiazepine derivative clorazepate on corticosterone secretion with its behavioural actions. Antagonism by Ro 15-1788. Pharmacol Biochem Behav. 1984 Dec; 21(6):839-43.
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Behavioural evidence for partial agonist properties of RO 15-1788, a benzodiazepine receptor antagonist. Eur J Pharmacol. 1982 Jul 30; 81(4):655-8.