"Connexins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of homologous proteins which form the intermembrane channels of GAP JUNCTIONS. The connexins are the products of an identified gene family which has both highly conserved and highly divergent regions. The variety contributes to the wide range of functional properties of gap junctions.
| Descriptor ID |
D017630
|
| MeSH Number(s) |
D12.776.543.585.250
|
| Concept/Terms |
Connexins- Connexins
- Gap Junction Protein
- Junction Protein, Gap
- Gap Junction Proteins
- Junction Proteins, Gap
- Gap Junction Channel Proteins
|
Below are MeSH descriptors whose meaning is more general than "Connexins".
Below are MeSH descriptors whose meaning is more specific than "Connexins".
This graph shows the total number of publications written about "Connexins" by people in this website by year, and whether "Connexins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 2 | 2 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 1 | 2 |
| 2005 | 2 | 0 | 2 |
| 2006 | 1 | 3 | 4 |
| 2007 | 2 | 1 | 3 |
| 2008 | 1 | 1 | 2 |
| 2009 | 1 | 4 | 5 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 1 | 2 |
| 2013 | 2 | 0 | 2 |
| 2014 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 1 | 1 | 2 |
| 2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Connexins" by people in Profiles.
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Regulation of Cx36 trafficking through the early secretory pathway by COPII cargo receptors and Grasp55. Cell Mol Life Sci. 2024 Oct 12; 81(1):431.
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Potentially functional variants of CHMP4A and PANX1 in the pyroptosis-related pathway predict survival of patients with non-oropharyngeal head and neck squamous cell carcinoma. Mol Carcinog. 2024 Sep; 63(9):1712-1721.
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Genetic analysis and natural history of Charcot-Marie-Tooth disease CMTX1 due to GJB1 variants. Brain. 2023 10 03; 146(10):4336-4349.
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Intralumenal docking of connexin 36 channels in the ER isolates mistrafficked protein. J Biol Chem. 2023 11; 299(11):105282.
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Knock-in mouse models for CMTX1 show a loss of function phenotype in the peripheral nervous system. Exp Neurol. 2023 02; 360:114277.
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Identification of pannexin 1-regulated genes, interactome, and pathways in rhabdomyosarcoma and its tumor inhibitory interaction with AHNAK. Oncogene. 2021 03; 40(10):1868-1883.
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Localized Calcium Signaling and the Control of Coupling at Cx36 Gap Junctions. eNeuro. 2020 Mar/Apr; 7(2).
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Conversion of human cardiac progenitor cells into cardiac pacemaker-like cells. J Mol Cell Cardiol. 2020 01; 138:12-22.
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A novel autosomal recessive GJB2-associated disorder: Ichthyosis follicularis, bilateral severe sensorineural hearing loss, and punctate palmoplantar keratoderma. Hum Mutat. 2019 02; 40(2):217-229.
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Live imaging of developing mouse retinal slices. Neural Dev. 2018 09 15; 13(1):23.