Receptors, Polymeric Immunoglobulin
"Receptors, Polymeric Immunoglobulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
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Specialized Fc receptors (RECEPTORS, FC) for polymeric immunoglobulins, which mediate transcytosis of polymeric IMMUNOGLOBULIN A and IMMUNOGLOBULIN M into external secretions. They are found on the surfaces of epithelial cells and hepatocytes. After binding to IMMUNOGLOBULIN A, the receptor-ligand complex undergoes endocytosis, transport by vesicle, and secretion into the lumen by exocytosis. Before release, the part of the receptor (SECRETORY COMPONENT) that is bound to IMMUNOGLOBULIN A is proteolytically cleaved from its transmembrane tail. (From Rosen et al., The Dictionary of Immunology, 1989)
| Descriptor ID |
D019056
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| MeSH Number(s) |
D12.776.543.750.705.871.700
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| Concept/Terms |
Receptors, Polymeric Immunoglobulin- Receptors, Polymeric Immunoglobulin
- Polymeric Immunoglobulin Receptors
- Immunoglobulin Receptors, Polymeric
- Receptor, Polyimmunoglobulin
- Receptor, Polymeric Ig
- Poly-Ig Receptor
- Poly Ig Receptor
- Receptor, Poly-Ig
- Polyimmunoglobulin Receptor
- Polymeric Immunoglobulin Receptor
- Immunoglobulin Receptor, Polymeric
- Receptor, Polymeric Immunoglobulin
- Polymeric Ig Receptor
- Ig Receptor, Polymeric
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Polymeric Immunoglobulin".
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This graph shows the total number of publications written about "Receptors, Polymeric Immunoglobulin" by people in this website by year, and whether "Receptors, Polymeric Immunoglobulin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, Polymeric Immunoglobulin" by people in Profiles.
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pIgR: frenemy of inflammation, EMT, and HCC progression. J Natl Cancer Inst. 2011 Nov 16; 103(22):1644-5.
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Integrated proteomic profiling of cell line conditioned media and pancreatic juice for the identification of pancreatic cancer biomarkers. Mol Cell Proteomics. 2011 Oct; 10(10):M111.008599.
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The human polymeric immunoglobulin receptor facilitates invasion of epithelial cells by Streptococcus pneumoniae in a strain-specific and cell type-specific manner. Infect Immun. 2002 Sep; 70(9):5091-5.
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Direct interaction between Rab3b and the polymeric immunoglobulin receptor controls ligand-stimulated transcytosis in epithelial cells. Dev Cell. 2002 Feb; 2(2):219-28.