Arachidonate 15-Lipoxygenase
"Arachidonate 15-Lipoxygenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the oxidation of arachidonic acid to yield 15-hydroperoxyarachidonate (15-HPETE) which is rapidly converted to 15-hydroxy-5,8,11,13-eicosatetraenoate (15-HETE). The 15-hydroperoxides are preferentially formed in NEUTROPHILS and LYMPHOCYTES.
| Descriptor ID |
D001093
|
| MeSH Number(s) |
D08.811.682.690.416.583.500.065 D12.776.556.579.374.568.500.030
|
| Concept/Terms |
Arachidonate 15-Lipoxygenase- Arachidonate 15-Lipoxygenase
- 15-Lipoxygenase, Arachidonate
- Arachidonate 15 Lipoxygenase
- Arachidonic Acid 15-Lipoxygenase
- 15-Lipoxygenase, Arachidonic Acid
- Arachidonic Acid 15 Lipoxygenase
- 15-Lipoxygenase
- 15 Lipoxygenase
|
Below are MeSH descriptors whose meaning is more general than "Arachidonate 15-Lipoxygenase".
Below are MeSH descriptors whose meaning is more specific than "Arachidonate 15-Lipoxygenase".
This graph shows the total number of publications written about "Arachidonate 15-Lipoxygenase" by people in this website by year, and whether "Arachidonate 15-Lipoxygenase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2000 | 2 | 0 | 2 |
| 2001 | 1 | 1 | 2 |
| 2002 | 2 | 0 | 2 |
| 2003 | 3 | 0 | 3 |
| 2004 | 1 | 0 | 1 |
| 2005 | 4 | 1 | 5 |
| 2006 | 2 | 1 | 3 |
| 2007 | 1 | 0 | 1 |
| 2008 | 3 | 0 | 3 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 2 | 0 | 2 |
| 2012 | 2 | 0 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 2 | 0 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Arachidonate 15-Lipoxygenase" by people in Profiles.
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EPA, DHA, and resolvin effects on cancer risk: The underexplored mechanisms. Prostaglandins Other Lipid Mediat. 2024 Oct; 174:106854.
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ALOX15 as a suppressor of inflammation and cancer: Lost in the link. Prostaglandins Other Lipid Mediat. 2017 09; 132:77-83.
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The role of 15-lipoxygenase-1 expression and its potential role in the pathogenesis of endometrial hyperplasia and endometrial adenocarcinomas. Eur J Gynaecol Oncol. 2016; 37(1):36-40.
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Antineoplastic effects of 15(S)-hydroxyeicosatetraenoic acid and 13-S-hydroxyoctadecadienoic acid in non-small cell lung cancer. Cancer. 2015 Sep 01; 121 Suppl 17:3130-45.
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A role for 12/15-lipoxygenase-derived proresolving mediators in postoperative ileus: protectin DX-regulated neutrophil extravasation. J Leukoc Biol. 2016 Feb; 99(2):231-9.
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15-Lipoxygenase-1 suppression of colitis-associated colon cancer through inhibition of the IL-6/STAT3 signaling pathway. FASEB J. 2015 Jun; 29(6):2359-70.
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15-LOX-1 suppression of hypoxia-induced metastatic phenotype and HIF-1a expression in human colon cancer cells. Cancer Med. 2014 Jun; 3(3):472-84.
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The expression of prostaglandin receptors EP3 and EP4 in human cervix in post-term pregnancy differs between failed and successful labor induction. Acta Obstet Gynecol Scand. 2014 Feb; 93(2):159-67.
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Eicosanoid profiling in colon cancer: emergence of a pattern. Prostaglandins Other Lipid Mediat. 2013 Jul-Aug; 104-105:139-43.
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Effects of gut-targeted 15-LOX-1 transgene expression on colonic tumorigenesis in mice. J Natl Cancer Inst. 2012 May 02; 104(9):709-16.