"Immunoglobulin J-Chains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 15 kD "joining" peptide that forms one of the linkages between monomers of IMMUNOGLOBULIN A or IMMUNOGLOBULIN M in the formation of polymeric immunoglobulins. There is one J chain per one IgA dimer or one IgM pentamer. It is also involved in binding the polymeric immunoglobulins to POLYMERIC IMMUNOGLOBULIN RECEPTOR which is necessary for their transcytosis to the lumen. It is distinguished from the IMMUNOGLOBULIN JOINING REGION which is part of the IMMUNOGLOBULIN VARIABLE REGION of the immunoglobulin light and heavy chains.
| Descriptor ID |
D007144
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| MeSH Number(s) |
D12.776.124.486.485.705.625 D12.776.124.790.651.705.625 D12.776.377.715.548.705.625
|
| Concept/Terms |
Immunoglobulin J-Chains- Immunoglobulin J-Chains
- Immunoglobulin J Chains
- J-Chains, Immunoglobulin
- J Chains, Immunoglobulin
- Immunoglobulin J-Peptide
- Immunoglobulin J Peptide
- J-Peptide, Immunoglobulin
- Ig J-Peptide
- Ig J Peptide
- J-Peptide, Ig
- Immunoglobulin J Polypeptide
- J Polypeptide, Immunoglobulin
- Polypeptide, Immunoglobulin J
|
Below are MeSH descriptors whose meaning is more general than "Immunoglobulin J-Chains".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin J-Chains".
This graph shows the total number of publications written about "Immunoglobulin J-Chains" by people in this website by year, and whether "Immunoglobulin J-Chains" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 2 | 2 |
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Below are the most recent publications written about "Immunoglobulin J-Chains" by people in Profiles.
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The B12/23 restriction is critically dependent on recombination signal nonamer and spacer sequences. J Immunol. 2003 Dec 15; 171(12):6604-10.
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Infant and adult human B cell responses to rotavirus share common immunodominant variable gene repertoires. J Immunol. 2003 Nov 01; 171(9):4680-8.
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Circulating human B cells that express surrogate light chains and edited receptors. Nat Immunol. 2000 Sep; 1(3):207-13.
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Z-138: a new mature B-cell acute lymphoblastic leukemia cell line from a patient with transformed chronic lymphocytic leukemia. Leuk Res. 1998 Apr; 22(4):341-53.
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The utility of the polymerase chain reaction as a screening method for the detection of antigen receptor gene rearrangements. Hum Pathol. 1994 Dec; 25(12):1261-3.
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Nonrandom use of J alpha gene segments. Influence of V alpha and J alpha gene location. J Immunol. 1991 Aug 01; 147(3):1075-81.
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Identification of three new Ig lambda-like genes in man. J Exp Med. 1986 Feb 01; 163(2):425-35.