GTP-Binding Protein alpha Subunits, Gq-G11
"GTP-Binding Protein alpha Subunits, Gq-G11" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of heterotrimeric GTP-binding protein alpha subunits that activate TYPE C PHOSPHOLIPASES dependent signaling pathways. The Gq-G11 part of the name is also spelled Gq/G11.
| Descriptor ID |
D043802
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| MeSH Number(s) |
D08.811.277.040.330.300.200.100.300 D12.644.360.360.100.300 D12.776.157.325.332.100.300 D12.776.476.375.100.300 D12.776.543.325.100.300
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| Concept/Terms |
GTP-Binding Protein alpha Subunits, Gq-G11- GTP-Binding Protein alpha Subunits, Gq-G11
- GTP Binding Protein alpha Subunits, Gq G11
- Gq-G11 G-Proteins
- G-Proteins, Gq-G11
- Gq G11 G Proteins
- Gq-G11 G-Protein Family
- Family, Gq-G11 G-Protein
- G-Protein Family, Gq-G11
- Gq G11 G Protein Family
- G-Protein, Gq-G11 alpha Family
- G Protein, Gq G11 alpha Family
- G-Protein, Gq-G11
- G Protein, Gq G11
- Gq-G11 G-Protein
GTP-Binding Protein alpha Subunit, Gq- GTP-Binding Protein alpha Subunit, Gq
- GTP Binding Protein alpha Subunit, Gq
- G alpha q Protein
- Galphaq Protein
- G-Protein, Gq
- G Protein, Gq
- Gq G-Protein
- G-Protein, Gq alpha Family
- G Protein, Gq alpha Family
- G alpha Protein q
- Gq Protein
GTP-Binding Protein alpha Subunit, G11- GTP-Binding Protein alpha Subunit, G11
- GTP Binding Protein alpha Subunit, G11
- G alpha11 Protein
- Protein, G alpha11
- alpha11 Protein, G
- Galpha11 Protein
- Protein, Galpha11
- G-Protein, G11
- G Protein, G11
- G11 G-Protein
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Below are MeSH descriptors whose meaning is more general than "GTP-Binding Protein alpha Subunits, Gq-G11".
Below are MeSH descriptors whose meaning is more specific than "GTP-Binding Protein alpha Subunits, Gq-G11".
This graph shows the total number of publications written about "GTP-Binding Protein alpha Subunits, Gq-G11" by people in this website by year, and whether "GTP-Binding Protein alpha Subunits, Gq-G11" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 2 | 0 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 1 | 2 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "GTP-Binding Protein alpha Subunits, Gq-G11" by people in Profiles.
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Trametinib in Patients With NF1-, GNAQ-, or GNA11-Mutant Tumors: Results From the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocols S1 and S2. JCO Precis Oncol. 2023 04; 7:e2200421.
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Assessing Gq-GPCR-induced human astrocyte reactivity using bioengineered neural organoids. J Cell Biol. 2022 02 09; 221(4).
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Intraocular Metastasis in Unilateral Multifocal Uveal Melanoma Without Melanocytosis or Germline BAP1 Mutations. JAMA Ophthalmol. 2019 12 01; 137(12):1434-1439.
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Minute-scale persistence of a GPCR conformation state triggered by non-cognate G protein interactions primes signaling. Nat Commun. 2019 10 23; 10(1):4836.
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Recurrent GNAQ mutation encoding T96S in natural killer/T cell lymphoma. Nat Commun. 2019 09 16; 10(1):4209.
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Conformational plasticity of the intracellular cavity of GPCR-G-protein complexes leads to G-protein promiscuity and selectivity. Proc Natl Acad Sci U S A. 2019 06 11; 116(24):11956-11965.
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Extracutaneous manifestations in phacomatosis cesioflammea and cesiomarmorata: Case series and literature review. Am J Med Genet A. 2019 06; 179(6):966-977.
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Use of Targeted Next-Generation Sequencing to Identify Activating Hot Spot Mutations in Cherry Angiomas. JAMA Dermatol. 2019 02 01; 155(2):211-215.
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Neratinib and entinostat combine to rapidly reduce the expression of K-RAS, N-RAS, Gaq and Ga11 and kill uveal melanoma cells. Cancer Biol Ther. 2019; 20(5):700-710.
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Activation of Gaq Signaling Enhances Memory Consolidation and Slows Cognitive Decline. Neuron. 2018 05 02; 98(3):562-574.e5.