Phosphofructokinase-1, Type C
"Phosphofructokinase-1, Type C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An allosteric enzyme that regulates glycolysis by catalyzing the transfer of a phosphate group from ATP to fructose-6-phosphate to yield fructose-1,6-bisphosphate. In the humans, 6-phosphofructose-1-kinase isozyme C is found in platelets, brain, heart, kidney, colon and testis. This isozyme C can exist as the homotetramer of C subunits (P subunits), or heterotetramer of C type and L type subunits.
| Descriptor ID |
D025502
|
| MeSH Number(s) |
D08.811.913.696.620.225.850.500.750
|
| Concept/Terms |
Phosphofructokinase-1, Type C- Phosphofructokinase-1, Type C
- Phosphofructokinase 1, Type C
- 6-Phosphofructokinase, Platelet Type
- Phosphofructo-1-kinase Isozyme C
|
Below are MeSH descriptors whose meaning is more general than "Phosphofructokinase-1, Type C".
Below are MeSH descriptors whose meaning is more specific than "Phosphofructokinase-1, Type C".
This graph shows the total number of publications written about "Phosphofructokinase-1, Type C" by people in this website by year, and whether "Phosphofructokinase-1, Type C" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phosphofructokinase-1, Type C" by people in Profiles.
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MiR-302 Regulates Glycolysis to Control Cell-Cycle during Neural Tube Closure. Int J Mol Sci. 2020 Oct 13; 21(20).
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EGFR-Phosphorylated Platelet Isoform of Phosphofructokinase 1 Promotes PI3K Activation. Mol Cell. 2018 04 19; 70(2):197-210.e7.
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Stabilization of phosphofructokinase 1 platelet isoform by AKT promotes tumorigenesis. Nat Commun. 2017 10 16; 8(1):949.
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Anti-human protein S antibody induces tissue factor expression through a direct interaction with platelet phosphofructokinase. Thromb Res. 2014 Feb; 133(2):222-8.
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Tat-activating regulatory DNA-binding protein regulates glycolysis in hepatocellular carcinoma by regulating the platelet isoform of phosphofructokinase through microRNA 520. Hepatology. 2013 Jul; 58(1):182-91.
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Oocyte-derived BMP15 and FGFs cooperate to promote glycolysis in cumulus cells. Development. 2007 Jul; 134(14):2593-603.