"Thyroxine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
| Descriptor ID |
D013974
|
| MeSH Number(s) |
D06.472.931.812 D12.125.072.050.767
|
| Concept/Terms |
Thyroxine- Thyroxine
- T4 Thyroid Hormone
- Thyroid Hormone, T4
- Thyroxin
- O-(4-Hydroxy-3,5-diiodophenyl) 3,5-diiodo-L-tyrosine
- L-3,5,3',5'-Tetraiodothyronine
- Levothyroxine
- L-Thyroxine
- L Thyroxine
- 3,5,3',5'-Tetraiodothyronine
- O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine
Levothyroxin Deladande- Levothyroxin Deladande
- Deladande, Levothyroxin
- Levothyroxin Delalande
- Delalande, Levothyroxin
|
Below are MeSH descriptors whose meaning is more general than "Thyroxine".
Below are MeSH descriptors whose meaning is more specific than "Thyroxine".
This graph shows the total number of publications written about "Thyroxine" by people in this website by year, and whether "Thyroxine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 2 | 2 |
| 2000 | 1 | 0 | 1 |
| 2002 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 2 | 1 | 3 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 2 | 3 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 2 | 2 |
| 2019 | 0 | 3 | 3 |
| 2020 | 0 | 1 | 1 |
| 2025 | 1 | 1 | 2 |
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click here.
Below are the most recent publications written about "Thyroxine" by people in Profiles.
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Structural insights into brain thyroid hormone transport via MCT8 and OATP1C1. Cell. 2025 Oct 02; 188(20):5576-5588.e17.
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Most elderly patients with subclinical hypothyroidism do not need to be treated. Cleve Clin J Med. 2025 Apr 01; 92(4):221-231.
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Graves' disease in a five-month-old boy with an unusual treatment course. J Pediatr Endocrinol Metab. 2021 Mar 26; 34(3):401-406.
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Trust your Endocrinologist - Report and Recommendations on the Ordering of Reverse T3 Testing. Ann Clin Lab Sci. 2020 May; 50(3):383-385.
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Nuclear corepressor SMRT is a strong regulator of body weight independently of its ability to regulate thyroid hormone action. PLoS One. 2019; 14(8):e0220717.
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Genetic and Pharmacological Targeting of Transcriptional Repression in Resistance to Thyroid Hormone Alpha. Thyroid. 2019 05; 29(5):726-734.
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Fetal thyroid disorders: Pathophysiology, diagnosis and therapeutic approaches. J Gynecol Obstet Hum Reprod. 2019 Apr; 48(4):231-233.
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Thyroid storm after choking. J Pediatr Endocrinol Metab. 2018 Aug 28; 31(8):933-936.
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Does initial dosing of levothyroxine in infants with congenital hypothyroidism lead to frequent dose adjustments secondary to iatrogenic hyperthyroidism on follow-up? J Pediatr Endocrinol Metab. 2018 Jun 27; 31(6):597-600.
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Inflammatory and neurohormonal modulation for congenital heart surgery: The quest continues. J Thorac Cardiovasc Surg. 2018 09; 156(3):1207-1208.