"Phenobarbital" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.
| Descriptor ID |
D010634
|
| MeSH Number(s) |
D03.383.742.698.253.650
|
| Concept/Terms |
Phenobarbital- Phenobarbital
- Phenylbarbital
- Phenylethylbarbituric Acid
- Acid, Phenylethylbarbituric
- Phenemal
- Phenobarbitone
Phenobarbital Sodium- Phenobarbital Sodium
- Sodium, Phenobarbital
- Phenobarbital, Monosodium Salt
- Monosodium Salt Phenobarbital
|
Below are MeSH descriptors whose meaning is more general than "Phenobarbital".
Below are MeSH descriptors whose meaning is more specific than "Phenobarbital".
This graph shows the total number of publications written about "Phenobarbital" by people in this website by year, and whether "Phenobarbital" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 1 | 2 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Phenobarbital" by people in Profiles.
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Involvement of GABAergic, glutamatergic, opioidergic, and brain-derived neurotrophic factor systems in the trigeminal neuropathic pain process. Neurosci Lett. 2023 01 10; 793:136970.
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Neuropsychological effects in children exposed to anticonvulsant monotherapy during gestation: Phenobarbital, carbamazepine, and phenytoin. Epilepsy Behav. 2022 02; 127:108533.
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Association between anti-seizure medication and outcomes in infants. J Perinatol. 2022 Mar; 42(3):359-364.
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First-line medication dosing in pediatric refractory status epilepticus. Neurology. 2020 11 10; 95(19):e2683-e2696.
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Impact of drug-drug interactions on phenobarbital pharmacokinetics in pediatric patients-Response. Epilepsia. 2019 06; 60(6):1268.
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Improved, Shorter-Latency Carcinogen-Induced Hepatocellular Carcinoma Model in Pigs. Oncology. 2018; 95(6):360-369.
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Phenobarbital population pharmacokinetics across the pediatric age spectrum. Epilepsia. 2018 07; 59(7):1327-1333.
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Changing antiepileptic drug use for seizures in US neonatal intensive care units from 2005 to 2014. J Perinatol. 2017 03; 37(3):296-300.
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The Case of the Previously Shaky, Unimmunized, Itchy Infant With Rash and Pancytopenia. Clin Pediatr (Phila). 2016 12; 55(14):1366-1368.
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Rab25 acts as an oncogene in luminal B breast cancer and is causally associated with Snail driven EMT. Oncotarget. 2016 Jun 28; 7(26):40252-40265.