"Ouabain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae; used like DIGITALIS. It is commonly used in cell biological studies as an inhibitor of the NA(+)-K(+)-EXCHANGING ATPASE.
| Descriptor ID |
D010042
|
| MeSH Number(s) |
D04.210.500.155.580.130.750.600 D09.408.180.810.600
|
| Concept/Terms |
Ouabain- Ouabain
- G-Strophanthin
- G Strophanthin
- Acocantherin
- Acolongifloroside K
|
Below are MeSH descriptors whose meaning is more general than "Ouabain".
Below are MeSH descriptors whose meaning is more specific than "Ouabain".
This graph shows the total number of publications written about "Ouabain" by people in this website by year, and whether "Ouabain" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 1 | 2 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ouabain" by people in Profiles.
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SGK3 Sensitivity of Voltage Gated K+ Channel Kv1.5 (KCNA5). Cell Physiol Biochem. 2016; 38(1):359-67.
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Cardiotonic steroids induce anti-angiogenic and anti-proliferative profiles in first trimester extravillous cytotrophoblast cells. Placenta. 2014 Nov; 35(11):932-6.
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Hypoxia limits inhibitory effects of Zn2+ on spreading depolarizations. PLoS One. 2013; 8(11):e75739.
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Nerium oleander derived cardiac glycoside oleandrin is a novel inhibitor of HIV infectivity. Fitoterapia. 2013 Jan; 84:32-9.
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Sodium ion channel mutations in glioblastoma patients correlate with shorter survival. Mol Cancer. 2011 Feb 11; 10:17.
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An optimized electrofusion-based protocol for generating virus-specific human monoclonal antibodies. J Immunol Methods. 2008 Jul 31; 336(2):142-51.
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Haploinsufficiency of ATP1A2 encoding the Na+/K+ pump alpha2 subunit associated with familial hemiplegic migraine type 2. Nat Genet. 2003 Feb; 33(2):192-6.
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Insulin increases the turnover rate of Na+-K+-ATPase in human fibroblasts. Am J Physiol Cell Physiol. 2001 Apr; 280(4):C912-9.
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The effects of potassium on the rat middle cerebral artery. Brain Res. 2000 Oct 13; 880(1-2):159-66.
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Colonic H-K-ATPase alpha- and beta-subunits express ouabain-insensitive H-K-ATPase. Am J Physiol Cell Physiol. 2000 Jan; 278(1):C182-9.