SOXD Transcription Factors
"SOXD Transcription Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of closely-related SOX transcription factors. In addition to a conserved HMG-BOX DOMAIN, members of this group contain a leucine zipper motif which mediates protein DIMERIZATION.
| Descriptor ID |
D055755
|
| MeSH Number(s) |
D12.776.260.719.400 D12.776.660.235.400.750.400 D12.776.664.235.400.750.400 D12.776.930.823.400
|
| Concept/Terms |
SOX6 Transcription Factor- SOX6 Transcription Factor
- Transcription Factor, SOX6
- SOX-6 Transcription Factor
- SOX 6 Transcription Factor
- Transcription Factor, SOX-6
SOX13 Transcription Factor- SOX13 Transcription Factor
- Transcription Factor, SOX13
- SOX-13 Transcription Factor
- SOX 13 Transcription Factor
- Transcription Factor, SOX-13
SOX5 Transcription Factor- SOX5 Transcription Factor
- Transcription Factor, SOX5
- SOX-5 Transcription Factor
- SOX 5 Transcription Factor
- Transcription Factor, SOX-5
|
Below are MeSH descriptors whose meaning is more general than "SOXD Transcription Factors".
Below are MeSH descriptors whose meaning is more specific than "SOXD Transcription Factors".
This graph shows the total number of publications written about "SOXD Transcription Factors" by people in this website by year, and whether "SOXD Transcription Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "SOXD Transcription Factors" by people in Profiles.
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Widening of the genetic and clinical spectrum of Lamb-Shaffer syndrome, a neurodevelopmental disorder due to SOX5 haploinsufficiency. Genet Med. 2020 03; 22(3):524-537.
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Haploinsufficiency of SOX5, a member of the SOX (SRY-related HMG-box) family of transcription factors is a cause of intellectual disability. Eur J Med Genet. 2013 Feb; 56(2):108-13.
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Haploinsufficiency of SOX5 at 12p12.1 is associated with developmental delays with prominent language delay, behavior problems, and mild dysmorphic features. Hum Mutat. 2012 Apr; 33(4):728-40.
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Sox9/Sox6 and Sp1 are involved in the insulin-like growth factor-I-mediated upregulation of human type II collagen gene expression in articular chondrocytes. J Mol Med (Berl). 2012 Jun; 90(6):649-66.
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Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo. Proc Natl Acad Sci U S A. 2005 Apr 05; 102(14):5062-7.
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The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Dev Cell. 2001 Aug; 1(2):277-90.
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L-Sox5, Sox6 and Sox9 control essential steps of the chondrocyte differentiation pathway. Osteoarthritis Cartilage. 2001; 9 Suppl A:S69-75.