"Glutathione Reductase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Catalyzes the oxidation of GLUTATHIONE to GLUTATHIONE DISULFIDE in the presence of NADP+. Deficiency in the enzyme is associated with HEMOLYTIC ANEMIA. Formerly listed as EC 1.6.4.2.
Descriptor ID |
D005980
|
MeSH Number(s) |
D08.811.682.667.092
|
Concept/Terms |
Glutathione Reductase- Glutathione Reductase
- Reductase, Glutathione
- Glutathione-Disulfide Reductase
- Reductase, Glutathione-Disulfide
|
Below are MeSH descriptors whose meaning is more general than "Glutathione Reductase".
Below are MeSH descriptors whose meaning is more specific than "Glutathione Reductase".
This graph shows the total number of publications written about "Glutathione Reductase" by people in this website by year, and whether "Glutathione Reductase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1999 | 1 | 0 | 1 |
2000 | 1 | 0 | 1 |
2003 | 0 | 1 | 1 |
2011 | 0 | 3 | 3 |
2013 | 0 | 2 | 2 |
2015 | 0 | 1 | 1 |
2018 | 1 | 0 | 1 |
2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Glutathione Reductase" by people in Profiles.
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Forced expression of miR-143 and -145 in cardiomyocytes induces cardiomyopathy with a reductive redox shift. Cell Mol Biol Lett. 2020; 25:40.
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AMPKa1 confers survival advantage of colorectal cancer cells under metabolic stress by promoting redox balance through the regulation of glutathione reductase phosphorylation. Oncogene. 2020 01; 39(3):637-650.
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Inhibition of Thioredoxin/Thioredoxin Reductase Induces Synthetic Lethality in Lung Cancers with Compromised Glutathione Homeostasis. Cancer Res. 2019 01 01; 79(1):125-132.
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Evaluation of antioxidant status of female diabetic patients in Nnamdi Azikiwe University Teaching Hospital, Anambra State, Nigeria. Br J Biomed Sci. 2015; 72(4):164-7.
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A high-salt diet further impairs age-associated declines in cognitive, behavioral, and cardiovascular functions in male Fischer brown Norway rats. J Nutr. 2013 Sep; 143(9):1406-13.
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Grape powder supplementation prevents oxidative stress-induced anxiety-like behavior, memory impairment, and high blood pressure in rats. J Nutr. 2013 Jun; 143(6):835-42.
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Potential contribution of oxidative stress and inflammation to anxiety and hypertension. Brain Res. 2011 Aug 02; 1404:63-71.
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Exercise prevents sleep deprivation-associated anxiety-like behavior in rats: potential role of oxidative stress mechanisms. Behav Brain Res. 2011 Oct 31; 224(2):233-40.
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Novel role of RGS2 in regulation of antioxidant homeostasis in neuronal cells. FEBS Lett. 2011 May 06; 585(9):1375-81.
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Kinetic and cellular characterization of novel inhibitors of S-nitrosoglutathione reductase. J Biol Chem. 2009 Sep 04; 284(36):24354-62.