"Berberine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An alkaloid from Hydrastis canadensis L., Berberidaceae. It is also found in many other plants. It is relatively toxic parenterally, but has been used orally for various parasitic and fungal infections and as antidiarrheal.
Descriptor ID |
D001599
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MeSH Number(s) |
D03.132.098.057.100 D03.633.400.168.100
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Berberine".
Below are MeSH descriptors whose meaning is more specific than "Berberine".
This graph shows the total number of publications written about "Berberine" by people in this website by year, and whether "Berberine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2006 | 1 | 0 | 1 |
2007 | 1 | 0 | 1 |
2008 | 2 | 0 | 2 |
2009 | 2 | 0 | 2 |
2010 | 2 | 0 | 2 |
2013 | 0 | 1 | 1 |
2020 | 0 | 1 | 1 |
2021 | 1 | 1 | 2 |
2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Berberine" by people in Profiles.
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Mucus-Penetrating Alginate-Chitosan Nanoparticles Loaded with Berberine Hydrochloride for Oral Delivery to the Inflammation Site of Ulcerative Colitis. AAPS PharmSciTech. 2022 Jun 27; 23(6):179.
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Berberine remodels adipose tissue to attenuate metabolic disorders by activating sirtuin 3. Acta Pharmacol Sin. 2022 May; 43(5):1285-1298.
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GSK-3? Can Regulate the Sensitivity of MIA-PaCa-2 Pancreatic and MCF-7 Breast Cancer Cells to Chemotherapeutic Drugs, Targeted Therapeutics and Nutraceuticals. Cells. 2021 04 06; 10(4).
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TP53/miR-34a-associated signaling targets SERPINE1 expression in human pancreatic cancer. Aging (Albany NY). 2020 01 27; 12(3):2777-2797.
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Endocannabinoid metabolism in the prefrontal cortex in schizophrenia. Schizophr Res. 2013 Jun; 147(1):53-57.
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Atrogin-1 affects muscle protein synthesis and degradation when energy metabolism is impaired by the antidiabetes drug berberine. Diabetes. 2010 Aug; 59(8):1879-89.
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CPU86017, a berberine derivative, attenuates cardiac failure through normalizing calcium leakage and downregulated phospholamban and exerting antioxidant activity. Acta Pharmacol Sin. 2010 Feb; 31(2):165-74.
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Berberine and plant stanols synergistically inhibit cholesterol absorption in hamsters. Atherosclerosis. 2010 Mar; 209(1):111-7.
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Butanol fraction containing berberine or related compound from nexrutine inhibits NFkappaB signaling and induces apoptosis in prostate cancer cells. Prostate. 2009 Apr 01; 69(5):494-504.
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CPU86017 and its isomers improve hypoxic pulmonary hypertension by attenuating increased ETA receptor expression and extracellular matrix accumulation. Naunyn Schmiedebergs Arch Pharmacol. 2008 Nov; 378(5):541-52.