"Thrombopoiesis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process of generating thrombocytes (BLOOD PLATELETS) from the pluripotent HEMATOPOIETIC STEM CELLS in the BONE MARROW via the MEGAKARYOCYTES. The humoral factor with thrombopoiesis-stimulating activity is designated THROMBOPOIETIN.
| Descriptor ID |
D034061
|
| MeSH Number(s) |
G04.152.825.798 G09.188.343.798
|
| Concept/Terms |
Thrombopoiesis- Thrombopoiesis
- Thrombopoieses
- Thrombocytopoiesis
- Thrombocytopoieses
|
Below are MeSH descriptors whose meaning is more general than "Thrombopoiesis".
Below are MeSH descriptors whose meaning is more specific than "Thrombopoiesis".
This graph shows the total number of publications written about "Thrombopoiesis" by people in this website by year, and whether "Thrombopoiesis" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 2 | 0 | 2 |
| 2014 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Thrombopoiesis" by people in Profiles.
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Platelet Dysfunction and Thrombosis in JAK2V617F-Mutated Primary Myelofibrotic Mice. Arterioscler Thromb Vasc Biol. 2020 10; 40(10):e262-e272.
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Identification of the Regulatory Elements and Target Genes of Megakaryopoietic Transcription Factor MEF2C. Thromb Haemost. 2019 May; 119(5):716-725.
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MicroRNAs 10a and 10b Regulate the Expression of Human Platelet Glycoprotein Iba for Normal Megakaryopoiesis. Int J Mol Sci. 2016 Nov 09; 17(11).
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Less Jak2 makes more platelets. Blood. 2014 Oct 02; 124(14):2168-9.
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Loss of Stat1 decreases megakaryopoiesis and favors erythropoiesis in a JAK2-V617F-driven mouse model of MPNs. Blood. 2014 Jun 19; 123(25):3943-50.
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SCL-mediated regulation of the cell-cycle regulator p21 is critical for murine megakaryopoiesis. Blood. 2011 Jul 21; 118(3):723-35.
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A randomized, double-blind study of romiplostim to determine its safety and efficacy in children with immune thrombocytopenia. Blood. 2011 Jul 07; 118(1):28-36.
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JAK2 V617F mutation is uncommon in patients with the 3q21q26 syndrome. Hum Pathol. 2010 May; 41(5):758-62.
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Thrombocytosis. Hematology Am Soc Hematol Educ Program. 2009; 159-67.
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Pronounced thrombocytosis in transgenic mice expressing reduced levels of Mpl in platelets and terminally differentiated megakaryocytes. Blood. 2009 Feb 19; 113(8):1768-77.