"Sex Differentiation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in developing sex- or gender-specific tissue, organ, or function after SEX DETERMINATION PROCESSES have set the sex of the GONADS. Major areas of sex differentiation occur in the reproductive tract (GENITALIA) and the brain.
| Descriptor ID |
D012733
|
| MeSH Number(s) |
G07.345.500.325.377.843 G07.345.750.500 G08.686.841.500
|
| Concept/Terms |
Sex Differentiation- Sex Differentiation
- Sexual Differentiation
- Differentiation, Sexual
- Differentiation, Sex
|
Below are MeSH descriptors whose meaning is more general than "Sex Differentiation".
Below are MeSH descriptors whose meaning is more specific than "Sex Differentiation".
This graph shows the total number of publications written about "Sex Differentiation" by people in this website by year, and whether "Sex Differentiation" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sex Differentiation" by people in Profiles.
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The Masc-PSI complex directly induces male-type doublesex splicing in silkworms. Commun Biol. 2025 Jun 14; 8(1):927.
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Fetal programming of polycystic ovary syndrome: Effects of androgen exposure on prenatal ovarian development. J Steroid Biochem Mol Biol. 2021 03; 207:105830.
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Nuclear Androgen Receptor Regulates Testes Organization and Oocyte Maturation in Zebrafish. Endocrinology. 2018 02 01; 159(2):980-993.
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Elimination of the male reproductive tract in the female embryo is promoted by COUP-TFII in mice. Science. 2017 08 18; 357(6352):717-720.
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Introduction. J Neuroendocrinol. 2016 07; 28(7).
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Activation of NF-?B protein prevents the transition from juvenile ovary to testis and promotes ovarian development in zebrafish. J Biol Chem. 2012 Nov 02; 287(45):37926-38.
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Child health, developmental plasticity, and epigenetic programming. Endocr Rev. 2011 Apr; 32(2):159-224.
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SOX9cre1, a cis-acting regulatory element located 1.1 Mb upstream of SOX9, mediates its enhancement through the SHH pathway. Hum Mol Genet. 2007 May 15; 16(10):1143-56.
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Combined haploinsufficiency of SF-1 and GATA4 does not reveal a genetic interaction in mouse gonadal development. Sex Dev. 2007; 1(3):152-60.
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Allocation and specification of the genital disc precursor cells in Drosophila. Dev Biol. 2005 May 15; 281(2):270-85.