NLRP3 (Nucleotide Oligomerization Domain-Like Receptor Family, Pyrin Domain Containing 3)-Caspase-1 Inflammasome Degrades Contractile Proteins: Implications for Aortic Biomechanical Dysfunction and Aneurysm and Dissection Formation.

NLRP3 (Nucleotide Oligomerization Domain-Like Receptor Family, Pyrin Domain Containing 3)-Caspase-1 Inflammasome Degrades Contractile Proteins: Implications for Aortic Biomechanical Dysfunction and Aneurysm and Dissection Formation. Arterioscler Thromb Vasc Biol. 2017 04; 37(4):694-706.

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subject areas

Aged
Angiotensin II
Animals
Aorta, Abdominal
Aorta, Thoracic
Aortic Aneurysm, Abdominal
Aortic Aneurysm, Thoracic
Biomechanical Phenomena
Caspase 1
Cells, Cultured
Disease Models, Animal
Female
Genetic Predisposition to Disease
Glyburide
Humans
Inflammasomes
Male
Mice, 129 Strain
Mice, Inbred C57BL
Mice, Knockout
Middle Aged
Muscle Proteins
Muscle, Smooth, Vascular
Myocytes, Smooth Muscle
NLR Family, Pyrin Domain-Containing 3 Protein
Phenotype
Proteolysis
Vasoconstriction

authors with profiles

SCOTT LEMAIRE
JOSEPH COSELLI