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Binimetinib inhibits MEK and is effective against neuroblastoma tumor cells with low NF1 expression.
Nonchromosomal birth defects and risk of childhood acute leukemia: An assessment in 15?000 leukemia cases and 46?000 controls from the Childhood Cancer and Leukemia International Consortium.
Regulation of NAA-synthesis in the human brain in vivo: Canavan's disease, Alzheimer's disease and schizophrenia.
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Binimetinib inhibits MEK and is effective against neuroblastoma tumor cells with low NF1 expression.
Binimetinib inhibits MEK and is effective against neuroblastoma tumor cells with low NF1 expression. BMC Cancer. 2016 Mar 01; 16:172.
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PubMed
subject areas
Benzimidazoles
Cell Line, Tumor
Dose-Response Relationship, Drug
Extracellular Signal-Regulated MAP Kinases
Gene Expression Regulation, Neoplastic
Humans
Neuroblastoma
Neurofibromin 1
Protein Kinase Inhibitors
ras Proteins
Signal Transduction
authors with profiles
SARAH WOODFIELD