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A first-in-human study of AMG 208, an oral MET inhibitor, in adult patients with advanced solid tumors.
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A first-in-human study of AMG 208, an oral MET inhibitor, in adult patients with advanced solid tumors.
A first-in-human study of AMG 208, an oral MET inhibitor, in adult patients with advanced solid tumors. Oncotarget. 2015 Jul 30; 6(21):18693-706.
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PubMed
subject areas
Administration, Oral
Adult
Aged
Aged, 80 and over
Area Under Curve
Biomarkers, Tumor
Dose-Response Relationship, Drug
Fatigue
Female
Humans
Hypertension
Immunohistochemistry
In Situ Hybridization, Fluorescence
Male
Metabolic Clearance Rate
Middle Aged
Nausea
Neoplasms
Protein Kinase Inhibitors
Proto-Oncogene Proteins c-met
Pyridazines
Remission Induction
Treatment Outcome
Triazoles
authors with profiles
SIQING FU
DAVID SANGHYUN HONG
FILIP JANKU