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Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia.
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Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia.
Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia. Cancer Discov. 2014 Mar; 4(3):362-75.
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PubMed
subject areas
Aniline Compounds
Animals
Antineoplastic Agents
Biomarkers, Tumor
Biphenyl Compounds
Bridged Bicyclo Compounds, Heterocyclic
Cell Death
Cell Line, Tumor
Drug Resistance, Neoplasm
Gene Expression Regulation, Leukemic
Humans
Leukemia, Myeloid, Acute
Mice
Mitochondria
Neoplasms, Experimental
Nitrophenols
Peptide Fragments
Piperazines
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-bcl-2
Sulfonamides
Xenograft Model Antitumor Assays
authors with profiles
MICHAEL ANDREEFF
HAGOP M KANTARJIAN
JORGE E CORTES
MARINA KONOPLEVA
PETER RUVOLO
GAUTAM BORTHAKUR
LINA HAN