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JING WANG

TitleAssociate Professor
InstitutionMD Anderson
DepartmentBioinformatics & Computational Biology
Address1400 Pressler St
Houston TX 77030-4008
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Tong P, Coombes KR, Johnson FM, Byers LA, Diao L, Liu DD, Lee JJ, Heymach JV, Wang J. drexplorer: A tool to explore dose-response relationships and drug-drug interactions. Bioinformatics. 2015 May 15; 31(10):1692-4. PMID: 25600946; PMCID: PMC4426846.
      Citations: 16     Fields:    
    2. Lin SH, Wang J, Saintigny P, Wu CC, Giri U, Zhang J, Menju T, Diao L, Byers L, Weinstein JN, Coombes KR, Girard L, Komaki R, Wistuba II, Date H, Minna JD, Heymach JV. Genes suppressed by DNA methylation in non-small cell lung cancer reveal the epigenetics of epithelial-mesenchymal transition. BMC Genomics. 2014 Dec 08; 15:1079. PMID: 25486910; PMCID: PMC4298954.
      Citations: 27     Fields:    Translation:HumansCells
    3. Cancer Genome Atlas Research Network. Comprehensive molecular profiling of lung adenocarcinoma. Nature. 2014 Jul 31; 511(7511):543-50. PMID: 25079552; PMCID: PMC4231481.
      Citations: 2046     Fields:    Translation:HumansCells
    4. Riquelme E, Suraokar M, Behrens C, Lin HY, Girard L, Nilsson MB, Simon G, Wang J, Coombes KR, Lee JJ, Hong WK, Heymach J, Minna JD, Wistuba II. VEGF/VEGFR-2 upregulates EZH2 expression in lung adenocarcinoma cells and EZH2 depletion enhances the response to platinum-based and VEGFR-2-targeted therapy. Clin Cancer Res. 2014 Jul 15; 20(14):3849-61. PMID: 24850841; PMCID: PMC4190586.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    5. Seguin L, Kato S, Franovic A, Camargo MF, Lesperance J, Elliott KC, Yebra M, Mielgo A, Lowy AM, Husain H, Cascone T, Diao L, Wang J, Wistuba II, Heymach JV, Lippman SM, Desgrosellier JS, Anand S, Weis SM, Cheresh DA. An integrin ?3-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition. Nat Cell Biol. 2014 May; 16(5):457-68. PMID: 24747441; PMCID: PMC4105198.
      Citations: 184     Fields:    Translation:HumansAnimalsCells
    6. Suraokar MB, Nunez MI, Diao L, Chow CW, Kim D, Behrens C, Lin H, Lee S, Raso G, Moran C, Rice D, Mehran R, Lee JJ, Pass HI, Wang J, Momin AA, James BP, Corvalan A, Coombes K, Tsao A, Wistuba II. Expression profiling stratifies mesothelioma tumors and signifies deregulation of spindle checkpoint pathway and microtubule network with therapeutic implications. Ann Oncol. 2014 Jun; 25(6):1184-92. PMID: 24669013; PMCID: PMC4037861.
      Citations: 26     Fields:    Translation:HumansCells
    7. Kadara H, Fujimoto J, Yoo SY, Maki Y, Gower AC, Kabbout M, Garcia MM, Chow CW, Chu Z, Mendoza G, Shen L, Kalhor N, Hong WK, Moran C, Wang J, Spira A, Coombes KR, Wistuba II. Transcriptomic architecture of the adjacent airway field cancerization in non-small cell lung cancer. J Natl Cancer Inst. 2014 Mar; 106(3):dju004. PMID: 24563515; PMCID: PMC3982778.
      Citations: 41     Fields:    Translation:HumansCells
    8. Zhao H, Sun Z, Wang J, Huang H, Kocher JP, Wang L. CrossMap: a versatile tool for coordinate conversion between genome assemblies. Bioinformatics. 2014 Apr 01; 30(7):1006-7. PMID: 24351709; PMCID: PMC3967108.
      Citations: 199     Fields:    Translation:HumansAnimalsCells
    9. Wang J, Byers LA. Teaching an old dog new tricks: drug repositioning in small cell lung cancer. Cancer Discov. 2013 Dec; 3(12):1333-5. PMID: 24327694; PMCID: PMC3878064.
      Citations: 6     Fields:    Translation:HumansAnimals
    10. Saintigny P, Liu S, Kim ES, Tsao AS, Herbst RS, Alden C, Lee JJ, Tang X, Stewart DJ, Kies MS, Fossella FV, Tran HT, Mao L, Hicks ME, Erasmus J, Gupta S, Girard L, Peyton M, Diao L, Wang J, Davis SE, Minna JD, Wistuba I, Hong WK, Heymach JV, Lippman SM, Blumenschein GR. Comprehensive biomarker analysis and final efficacy results of sorafenib in the BATTLE trial. Clin Cancer Res. 2013 Dec 15; 19(24):6967-75. PMID: 24166906; PMCID: PMC3905243.
      Citations: 28     Fields:    Translation:Humans
    11. Cardnell RJ, Feng Y, Diao L, Fan YH, Masrorpour F, Wang J, Shen Y, Mills GB, Minna JD, Heymach JV, Byers LA. Proteomic markers of DNA repair and PI3K pathway activation predict response to the PARP inhibitor BMN 673 in small cell lung cancer. Clin Cancer Res. 2013 Nov 15; 19(22):6322-8. PMID: 24077350; PMCID: PMC3882158.
      Citations: 90     Fields:    Translation:HumansAnimalsCells
    12. Wang J, Wu X, Kamat A, Barton Grossman H, Dinney CP, Lin J. Fluid intake, genetic variants of UDP-glucuronosyltransferases, and bladder cancer risk. Br J Cancer. 2013 Jun 11; 108(11):2372-80. PMID: 23632476; PMCID: PMC3681021.
      Citations: 13     Fields:    Translation:Humans
    13. Lin X, Liu B, Yang X, Yue X, Diao L, Wang J, Chang J. Genetic deletion of Rnd3 results in aqueductal stenosis leading to hydrocephalus through up-regulation of Notch signaling. Proc Natl Acad Sci U S A. 2013 May 14; 110(20):8236-41. PMID: 23630292; PMCID: PMC3657816.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    14. Wang J, Myles B, Wei C, Chang JY, Hofstetter WL, Ajani JA, Swisher SG, Cox JD, Komaki R, Liao Z, Lin SH. Obesity and outcomes in patients treated with chemoradiotherapy for esophageal carcinoma. Dis Esophagus. 2014 Feb-Mar; 27(2):168-75. PMID: 23621168; PMCID: PMC3740061.
      Citations: 6     Fields:    Translation:Humans
    15. Pickering CR, Zhang J, Yoo SY, Bengtsson L, Moorthy S, Neskey DM, Zhao M, Ortega Alves MV, Chang K, Drummond J, Cortez E, Xie TX, Zhang D, Chung W, Issa JP, Zweidler-McKay PA, Wu X, El-Naggar AK, Weinstein JN, Wang J, Muzny DM, Gibbs RA, Wheeler DA, Myers JN, Frederick MJ. Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers. Cancer Discov. 2013 Jul; 3(7):770-81. PMID: 23619168; PMCID: PMC3858325.
      Citations: 241     Fields:    Translation:HumansCells
    16. Kim YW, Koul D, Kim SH, Lucio-Eterovic AK, Freire PR, Yao J, Wang J, Almeida JS, Aldape K, Yung WK. Identification of prognostic gene signatures of glioblastoma: a study based on TCGA data analysis. Neuro Oncol. 2013 Jul; 15(7):829-39. PMID: 23502430; PMCID: PMC3688008.
      Citations: 51     Fields:    Translation:Humans
    17. Chauhan S, Goodwin JG, Chauhan S, Manyam G, Wang J, Kamat AM, Boyd DD. ZKSCAN3 is a master transcriptional repressor of autophagy. Mol Cell. 2013 Apr 11; 50(1):16-28. PMID: 23434374; PMCID: PMC3628091.
      Citations: 125     Fields:    Translation:HumansCells
    18. Yan W, Shih J, Rodriguez-Canales J, Tangrea MA, Player A, Diao L, Hu N, Goldstein AM, Wang J, Taylor PR, Lippman SM, Wistuba II, Emmert-Buck MR, Erickson HS. Three-dimensional mRNA measurements reveal minimal regional heterogeneity in esophageal squamous cell carcinoma. Am J Pathol. 2013 Feb; 182(2):529-39. PMID: 23219752; PMCID: PMC3562732.
      Citations: 3     Fields:    Translation:HumansCells
    19. Byers LA, Diao L, Wang J, Saintigny P, Girard L, Peyton M, Shen L, Fan Y, Giri U, Tumula PK, Nilsson MB, Gudikote J, Tran H, Cardnell RJ, Bearss DJ, Warner SL, Foulks JM, Kanner SB, Gandhi V, Krett N, Rosen ST, Kim ES, Herbst RS, Blumenschein GR, Lee JJ, Lippman SM, Ang KK, Mills GB, Hong WK, Weinstein JN, Wistuba II, Coombes KR, Minna JD, Heymach JV. An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance. Clin Cancer Res. 2013 Jan 01; 19(1):279-90. PMID: 23091115; PMCID: PMC3567921.
      Citations: 463     Fields:    Translation:HumansAnimalsCells
    20. Kadara H, Shen L, Fujimoto J, Saintigny P, Chow CW, Lang W, Chu Z, Garcia M, Kabbout M, Fan YH, Behrens C, Liu DA, Mao L, Lee JJ, Gold KA, Wang J, Coombes KR, Kim ES, Hong WK, Wistuba II. Characterizing the molecular spatial and temporal field of injury in early-stage smoker non-small cell lung cancer patients after definitive surgery by expression profiling. Cancer Prev Res (Phila). 2013 Jan; 6(1):8-17. PMID: 23087048; PMCID: PMC3774536.
      Citations: 22     Fields:    Translation:HumansCellsCTClinical Trials
    21. Byers LA, Wang J, Nilsson MB, Fujimoto J, Saintigny P, Yordy J, Giri U, Peyton M, Fan YH, Diao L, Masrorpour F, Shen L, Liu W, Duchemann B, Tumula P, Bhardwaj V, Welsh J, Weber S, Glisson BS, Kalhor N, Wistuba II, Girard L, Lippman SM, Mills GB, Coombes KR, Weinstein JN, Minna JD, Heymach JV. Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1. Cancer Discov. 2012 Sep; 2(9):798-811. PMID: 22961666; PMCID: PMC3567922.
      Citations: 217     Fields:    Translation:HumansCells
    22. Adam L, Wszolek MF, Liu CG, Jing W, Diao L, Zien A, Zhang JD, Jackson D, Dinney CP. Plasma microRNA profiles for bladder cancer detection. Urol Oncol. 2013 Nov; 31(8):1701-8. PMID: 22863868; PMCID: PMC5226073.
      Citations: 40     Fields:    Translation:HumansCells
    23. Yang J, He J, Wang J, Cao Y, Ling J, Qian J, Lu Y, Li H, Zheng Y, Lan Y, Hong S, Matthews J, Starbuck MW, Navone NM, Orlowski RZ, Lin P, Kwak LW, Yi Q. Constitutive activation of p38 MAPK in tumor cells contributes to osteolytic bone lesions in multiple myeloma. Leukemia. 2012 Sep; 26(9):2114-23. PMID: 22425892; PMCID: PMC3381862.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    24. He Y, Zhou Z, Hofstetter WL, Zhou Y, Hu W, Guo C, Wang L, Guo W, Pataer A, Correa AM, Lu Y, Wang J, Diao L, Byers LA, Wistuba II, Roth JA, Swisher SG, Heymach JV, Fang B. Aberrant expression of proteins involved in signal transduction and DNA repair pathways in lung cancer and their association with clinical parameters. PLoS One. 2012; 7(2):e31087. PMID: 22348039; PMCID: PMC3277494.
      Citations: 28     Fields:    Translation:HumansCells
    25. Wan X, Liu J, Lu JF, Tzelepi V, Yang J, Starbuck MW, Diao L, Wang J, Efstathiou E, Vazquez ES, Troncoso P, Maity SN, Navone NM. Activation of ?-catenin signaling in androgen receptor-negative prostate cancer cells. Clin Cancer Res. 2012 Feb 01; 18(3):726-36. PMID: 22298898; PMCID: PMC3271798.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    26. Ihle NT, Byers LA, Kim ES, Saintigny P, Lee JJ, Blumenschein GR, Tsao A, Liu S, Larsen JE, Wang J, Diao L, Coombes KR, Chen L, Zhang S, Abdelmelek MF, Tang X, Papadimitrakopoulou V, Minna JD, Lippman SM, Hong WK, Herbst RS, Wistuba II, Heymach JV, Powis G. Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome. J Natl Cancer Inst. 2012 Feb 08; 104(3):228-39. PMID: 22247021; PMCID: PMC3274509.
      Citations: 199     Fields:    Translation:HumansCells
    27. Agrawal N, Frederick MJ, Pickering CR, Bettegowda C, Chang K, Li RJ, Fakhry C, Xie TX, Zhang J, Wang J, Zhang N, El-Naggar AK, Jasser SA, Weinstein JN, Drummond JA, Muzny DM, Wu Y, Wood LD, Hruban RH, Westra WH, Koch WM, Califano JA, Gibbs RA, Sidransky D, Vogelstein B, Velculescu VE, Papadopoulos N, Wheeler DA, Kinzler KW, Myers JN, Trevi?o L. Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1. Science. 2011 Aug 26; 333(6046):1154-7. PMID: 21798897; PMCID: PMC3162986.
      Citations: 840     Fields:    Translation:HumansAnimalsCells
    28. Karn T, Pusztai L, Liedtke C, Schmidt M, Metzler D, Wang J, Coombes KR, Hanker L, Solbach C, Ahr A, Holtrich U, Rody A, Kaufmann M, Ruckh?berle E, M?ller V, G?tje R. Melanoma antigen family A identified by the bimodality index defines a subset of triple negative breast cancers as candidates for immune response augmentation. Eur J Cancer. 2012 Jan; 48(1):12-23. PMID: 21741824.
      Citations: 25     Fields:    Translation:Humans
    29. Yang F, Tang X, Riquelme E, Behrens C, Nilsson MB, Giri U, Varella-Garcia M, Byers LA, Lin HY, Wang J, Raso MG, Girard L, Coombes K, Lee JJ, Herbst RS, Minna JD, Heymach JV, Wistuba II. Increased VEGFR-2 gene copy is associated with chemoresistance and shorter survival in patients with non-small-cell lung carcinoma who receive adjuvant chemotherapy. Cancer Res. 2011 Aug 15; 71(16):5512-21. PMID: 21724587; PMCID: PMC3159530.
      Citations: 29     Fields:    Translation:Humans
    30. Zhou W, Bolden-Tiller OU, Shao SH, Weng CC, Shetty G, AbuElhija M, Pakarinen P, Huhtaniemi I, Momin AA, Wang J, Stivers DN, Liu Z, Meistrich ML. Estrogen-regulated genes in rat testes and their relationship to recovery of spermatogenesis after irradiation. Biol Reprod. 2011 Oct; 85(4):823-33. PMID: 21653891; PMCID: PMC3184294.
      Citations: 6     Fields:    Translation:Animals
    31. Tabata K, Kurosaka S, Watanabe M, Edamura K, Satoh T, Yang G, Abdelfattah E, Wang J, Goltsov A, Floryk D, Thompson TC. Tumor growth and metastasis suppression by Glipr1 gene-modified macrophages in a metastatic prostate cancer model. Gene Ther. 2011 Oct; 18(10):969-78. PMID: 21512508; PMCID: PMC3881531.
      Citations: 4     Fields:    Translation:AnimalsCells
    32. Kim YW, Liu TJ, Koul D, Tiao N, Feroze AH, Wang J, Powis G, Yung WK. Identification of novel synergistic targets for rational drug combinations with PI3 kinase inhibitors using siRNA synthetic lethality screening against GBM. Neuro Oncol. 2011 Apr; 13(4):367-75. PMID: 21430111; PMCID: PMC3064700.
      Citations: 20     Fields:    Translation:HumansCells
    33. Frederick MJ, VanMeter AJ, Gadhikar MA, Henderson YC, Yao H, Pickering CC, Williams MD, El-Naggar AK, Sandulache V, Tarco E, Myers JN, Clayman GL, Liotta LA, Petricoin EF, Calvert VS, Fodale V, Wang J, Weber RS. Phosphoproteomic analysis of signaling pathways in head and neck squamous cell carcinoma patient samples. Am J Pathol. 2011 Feb; 178(2):548-71. PMID: 21281788; PMCID: PMC3070553.
      Citations: 16     Fields:    Translation:HumansCells
    34. Nanjundan M, Byers LA, Carey MS, Siwak DR, Raso MG, Diao L, Wang J, Coombes KR, Roth JA, Mills GB, Wistuba II, Minna JD, Heymach JV. Proteomic profiling identifies pathways dysregulated in non-small cell lung cancer and an inverse association of AMPK and adhesion pathways with recurrence. J Thorac Oncol. 2010 Dec; 5(12):1894-904. PMID: 21124077; PMCID: PMC3374718.
      Citations: 27     Fields:    Translation:HumansCells
    35. Wang J, Byers LA, Yordy JS, Liu W, Shen L, Baggerly KA, Giri U, Myers JN, Ang KK, Story MD, Girard L, Minna JD, Heymach JV, Coombes KR. Blasted cell line names. Cancer Inform. 2010 Oct 14; 9:251-5. PMID: 21082038; PMCID: PMC2978931.
      Citations:    
    36. Hudson LG, Gale JM, Padilla RS, Pickett G, Alexander BE, Wang J, Kusewitt DF. Microarray analysis of cutaneous squamous cell carcinomas reveals enhanced expression of epidermal differentiation complex genes. Mol Carcinog. 2010 Jul; 49(7):619-29. PMID: 20564339; PMCID: PMC3626076.
      Citations: 20     Fields:    Translation:Humans
    37. Shiang CY, Qi Y, Wang B, Lazar V, Wang J, Fraser Symmans W, Hortobagyi GN, Andre F, Pusztai L. Amplification of fibroblast growth factor receptor-1 in breast cancer and the effects of brivanib alaninate. Breast Cancer Res Treat. 2010 Oct; 123(3):747-55. PMID: 20024612.
      Citations: 14     Fields:    Translation:HumansCells
    38. Byers LA, Sen B, Saigal B, Diao L, Wang J, Nanjundan M, Cascone T, Mills GB, Heymach JV, Johnson FM. Reciprocal regulation of c-Src and STAT3 in non-small cell lung cancer. Clin Cancer Res. 2009 Nov 15; 15(22):6852-61. PMID: 19861436; PMCID: PMC2935176.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    39. Wang J, Wen S, Symmans WF, Pusztai L, Coombes KR. The bimodality index: a criterion for discovering and ranking bimodal signatures from cancer gene expression profiling data. Cancer Inform. 2009 Aug 05; 7:199-216. PMID: 19718451; PMCID: PMC2730180.
      Citations: 61     
    40. Liedtke C, Wang J, Tordai A, Symmans WF, Hortobagyi GN, Kiesel L, Hess K, Baggerly KA, Coombes KR, Pusztai L. Clinical evaluation of chemotherapy response predictors developed from breast cancer cell lines. Breast Cancer Res Treat. 2010 Jun; 121(2):301-9. PMID: 19603265.
      Citations: 23     Fields:    Translation:HumansCells
    41. Li ZG, Mathew P, Yang J, Starbuck MW, Zurita AJ, Liu J, Sikes C, Multani AS, Efstathiou E, Lopez A, Wang J, Fanning TV, Prieto VG, Kundra V, Vazquez ES, Troncoso P, Raymond AK, Logothetis CJ, Lin SH, Maity S, Navone NM. Androgen receptor-negative human prostate cancer cells induce osteogenesis in mice through FGF9-mediated mechanisms. J Clin Invest. 2008 Aug; 118(8):2697-710. PMID: 18618013; PMCID: PMC2447924.
      Citations: 105     Fields:    Translation:HumansAnimalsCells
    42. Tordai A, Wang J, Andre F, Liedtke C, Yan K, Sotiriou C, Hortobagyi GN, Symmans WF, Pusztai L. Evaluation of biological pathways involved in chemotherapy response in breast cancer. Breast Cancer Res. 2008; 10(2):R37. PMID: 18445275; PMCID: PMC2397539.
      Citations: 27     Fields:    Translation:HumansCells
    43. Coombes KR, Wang J, Baggerly KA. Microarrays: retracing steps. Nat Med. 2007 Nov; 13(11):1276-7; author reply 1277-8. PMID: 17987014.
      Citations: 46     Fields:    Translation:HumansCells
    44. Liu W, Vyas A, Escalante C, Weiser MA, Wang J, Geraci JM. Results of general internal medicine consultations for diabetes mellitus in 283 cancer patients. Am J Med Sci. 2007 May; 333(5):276-9. PMID: 17505168.
      Citations: 2     Fields:    Translation:Humans
    45. Wang J, Do KA, Wen S, Tsavachidis S, McDonnell TJ, Logothetis CJ, Coombes KR. Merging microarray data, robust feature selection, and predicting prognosis in prostate cancer. Cancer Inform. 2007 Feb 14; 2:87-97. PMID: 19458761; PMCID: PMC2675498.
      Citations: 14     
    46. Esteva FJ, Wang J, Lin F, Mejia JA, Yan K, Altundag K, Valero V, Buzdar AU, Hortobagyi GN, Symmans WF, Pusztai L. CD40 signaling predicts response to preoperative trastuzumab and concomitant paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide in HER-2-overexpressing breast cancer. Breast Cancer Res. 2007; 9(6):R87. PMID: 18086299; PMCID: PMC2246190.
      Citations: 14     Fields:    Translation:HumansCells
    47. Gold DL, Coombes KR, Wang J, Mallick B. Enrichment analysis in high-throughput genomics - accounting for dependency in the NULL. Brief Bioinform. 2007 Mar; 8(2):71-7. PMID: 17077137.
      Citations: 11     Fields:    Translation:Cells
    48. Kupferman ME, Patel V, Sriuranpong V, Amornphimoltham P, Jasser SA, Mandal M, Zhou G, Wang J, Coombes K, Multani A, Pathak S, Silvio Gutkind J, Myers JN. Molecular analysis of anoikis resistance in oral cavity squamous cell carcinoma. Oral Oncol. 2007 May; 43(5):440-54. PMID: 16978912.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    49. Ji Y, Coombes K, Zhang J, Wen S, Mitchell J, Pusztai L, Symmans WF, Wang J. RefSeq refinements of UniGene-based gene matching improve the correlation of expression measurements between two microarray platforms. Appl Bioinformatics. 2006; 5(2):89-98. PMID: 16722773.
      Citations: 3     Fields:    Translation:HumansCells
    50. Abruzzo LV, Wang J, Kapoor M, Medeiros LJ, Keating MJ, Edward Highsmith W, Barron LL, Cromwell CC, Coombes KR. Biological validation of differentially expressed genes in chronic lymphocytic leukemia identified by applying multiple statistical methods to oligonucleotide microarrays. J Mol Diagn. 2005 Aug; 7(3):337-45. PMID: 16049305; PMCID: PMC1867538.
      Citations: 4     Fields:    Translation:HumansCells
    51. Stec J, Wang J, Coombes K, Ayers M, Hoersch S, Gold DL, Ross JS, Hess KR, Tirrell S, Linette G, Hortobagyi GN, Fraser Symmans W, Pusztai L. Comparison of the predictive accuracy of DNA array-based multigene classifiers across cDNA arrays and Affymetrix GeneChips. J Mol Diagn. 2005 Aug; 7(3):357-67. PMID: 16049308; PMCID: PMC1867535.
      Citations: 16     Fields:    Translation:Humans
    52. Ji Y, Wu C, Liu P, Wang J, Coombes KR. Applications of beta-mixture models in bioinformatics. Bioinformatics. 2005 May 01; 21(9):2118-22. PMID: 15713737.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    53. Gold DL, Wang J, Coombes KR. Inter-gene correlation on oligonucleotide arrays: how much does normalization matter? Am J Pharmacogenomics. 2005; 5(4):271-9. PMID: 16078863.
      Citations: 5     Fields:    
    54. Wang J, Coombes KR, Highsmith WE, Keating MJ, Abruzzo LV. Differences in gene expression between B-cell chronic lymphocytic leukemia and normal B cells: a meta-analysis of three microarray studies. Bioinformatics. 2004 Nov 22; 20(17):3166-78. PMID: 15231529.
      Citations: 54     Fields:    Translation:Humans
    55. Baggerly KA, Morris JS, Wang J, Gold D, Xiao LC, Coombes KR. A comprehensive approach to the analysis of matrix-assisted laser desorption/ionization-time of flight proteomics spectra from serum samples. Proteomics. 2003 Sep; 3(9):1667-72. PMID: 12973722.
      Citations: 40     Fields:    Translation:Humans
    56. McCarthy H, Wierda WG, Barron LL, Cromwell CC, Wang J, Coombes KR, Rangel R, Elenitoba-Johnson KS, Keating MJ, Abruzzo LV. High expression of activation-induced cytidine deaminase (AID) and splice variants is a distinctive feature of poor-prognosis chronic lymphocytic leukemia. Blood. 2003 Jun 15; 101(12):4903-8. PMID: 12586616.
      Citations: 46     Fields:    Translation:HumansCells
    57. Wang J, Hu L, Hamilton SR, Coombes KR, Zhang W. RNA amplification strategies for cDNA microarray experiments. Biotechniques. 2003 Feb; 34(2):394-400. PMID: 12613262.
      Citations: 17     Fields:    Translation:Humans
    58. Chowdhury SF, Sivaraman J, Wang J, Devanathan G, Lachance P, Qi H, Lefebvre J, Konishi Y, Cygler M, Sulea T, Purisima EO, M?nard R. Design of noncovalent inhibitors of human cathepsin L. From the 96-residue proregion to optimized tripeptides. J Med Chem. 2002 Nov 21; 45(24):5321-9. PMID: 12431059.
      Citations: 18     Fields:    Translation:HumansCells
    59. Wang J, Geng YJ, Guo B, Klima T, Lal BN, Willerson JT, Casscells W. Near-infrared spectroscopic characterization of human advanced atherosclerotic plaques. J Am Coll Cardiol. 2002 Apr 17; 39(8):1305-13. PMID: 11955848.
      Citations: 31     Fields:    Translation:HumansAnimals
    60. Ramdas L, Wang J, Hu L, Cogdell D, Taylor E, Zhang W. Comparative evaluation of laser-based microarray scanners. Biotechniques. 2001 Sep; 31(3):546, 548, 550, passim. PMID: 11570499.
      Citations:    Fields:    Translation:Cells
    61. Illy C, Quraishi O, Wang J, Purisima E, Vernet T, Mort JS. Role of the occluding loop in cathepsin B activity. J Biol Chem. 1997 Jan 10; 272(2):1197-202. PMID: 8995421.
      Citations: 70     Fields:    Translation:HumansCells
    62. Cheng Y, Slon-Usakiewicz JJ, Wang J, Purisima EO, Konishi Y. Nonpolar interactions of thrombin and its inhibitors at the fibrinogen recognition exosite: thermodynamic analysis. Biochemistry. 1996 Oct 08; 35(40):13021-9. PMID: 8855937.
      Citations: 2     Fields:    Translation:HumansCells
    63. Wang J, Szewczuk Z, Yue SY, Tsuda Y, Konishi Y, Purisima EO. Calculation of relative binding free energies and configurational entropies: a structural and thermodynamic analysis of the nature of non-polar binding of thrombin inhibitors based on hirudin55-65. J Mol Biol. 1995 Oct 27; 253(3):473-92. PMID: 7473728.
      Citations: 12     Fields:    Translation:HumansCells
    64. Comparison of different infrared measurement techniques in the clinical analysis of biofluids. TrAC - Trends in Analytical Chemistry. 15:286-296.
    65. Polo-like kinase 1 inhibition diminishes acquired resistance to epidermal growth factor receptor inhibition in non-small cell lung cancer with T790M mutations. Oncotarget. 7:47998-48010.
    66. Exogenous restoration of TUSC2 expression induces responsiveness to erlotinib in wildtype epidermal growth factor receptor (EGFR) lung cancer cells through context specific pathways resulting in enhanced therapeutic efficacy. PLoS One. 10.
    67. TUSC2(FUS1)-erlotinib Induced Vulnerabilities in Epidermal Growth Factor Receptor(EGFR) Wildtype Non-small Cell Lung Cancer(NSCLC) Targeted by the Repurposed Drug Auranofin. Scientific Reports. 6.
    68. Thermodynamic investigation of enzyme and inhibitor interactions with high affinity. Techniques in Protein Chemistry. 8:513-521.
    69. Epithelial-mesenchymal transition is associated with a distinct tumor microenvironment including elevation of inflammatory signals and multiple immune checkpoints in lung adenocarcinoma. Clinical Cancer Research. 22:3630-3642.
    70. Selecting reliable mRNA expression measurements across platforms improves downstream analysis. Cancer Informatics. 15:81-89.
    71. High-resolution profiling of histone h3 lysine 36 trimethylation in metastatic renal cell carcinoma. Oncogene.
    72. An integrated molecular analysis of lung adenocarcinomas identifies potential therapeutic targets among TTF1-negative tumors, including DNA Repair Proteins and Nrf2. Clinical Cancer Research. 21:3480-3491.
    73. Photoacoustic near-infrared investigation of homo-polypeptides. Journal of Physical Chemistry. 98:4748-4755.
    74. A Patient-Derived, Pan-Cancer EMT Signature Identifies Global Molecular Alterations and Immune Target Enrichment Following Epithelial-to-Mesenchymal Transition. Clinical Cancer Research. 22:609-620.
    75. KDR amplification is associated with VEGF-induced activation of the mTOR and invasion pathways but does not predict clinical benefit to the VEGFR TKI vandetanib. Clinical Cancer Research. 22:1940-1950.
    76. Hsp90 inhibitor ganetespib sensitizes non-small cell lung cancer to radiation but has variable effects with chemoradiation. Clinical Cancer Research. 22:5876-5886.
    77. Intelligent clinical decision support systems for non-invasive bladder cancer diagnosis. 253-262.
    78. FT-IR spectra of glycine oligomers. Vibrational Spectroscopy. 14:143-146.
    79. Statistical considerations in the assessment of cDNA microarray data obtained using amplification. 21-36.
    80. Growth and metastasis of lung adenocarcinoma is potentiated by BMP4-mediated immunosuppression. OncoImmunology.
    81. STK11/LKB1 deficiency promotes neutrophil recruitment and proinflammatory cytokine production to suppress T-cell activity in the lung tumor microenvironment. Cancer Research. 76:999-1008.
    82. AXL inhibition suppresses the DNA damage response and sensitizes cells to PARP inhibition in multiple cancers. Molecular Cancer Research. 15:45-58.
    83. Infrared spectroscopic investigation of in vivo and ex vivo human nails. Vibrational Spectroscopy. 10:49-56.
    84. Epithelial-mesenchymal transition predicts polo-like kinase 1 inhibitor-mediated apoptosis in non-small cell lung cancer. Clinical Cancer Research. 22:1674-1686.
    85. New DNA methylation markers and global DNA hypomethylation are associated with oral cancer development. Cancer Prevention Research. 8:1027-1035.
    86. Genomic landscape established by allelic imbalance in the cancerization field of a normal appearing airway. Cancer Research. 76:3676-3683.
    87. The BATTLE-2 study. Journal of Clinical Oncology. 34:3638-3647.
    88. MicroRNA expression profiling identifies decreased expression of miR-205 in inflammatory breast cancer. Modern Pathology.
    89. Analysis of thermodynamic determinants in helix propensities of nonpolar amino acids through a novel free energy calculation. Journal of the American Chemical Society. 118:995-1001.
    90. Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities. Cancer Discovery. 5:861-878.
    91. Proteomic profiling identifies PTK2/FAK as a driver of radioresistance in HPV-negative head and neck cancer. Clinical Cancer Research. 22:4643-4650.
    92. Loss of histone H3 lysine 36 trimethylation is associated with an increased risk of renal cell carcinoma-specific death. Modern Pathology. 29:34-42.
    93. Genes suppressed by DNA methylation in non-small cell lung cancer reveal the epigenetics of epithelial-mesenchymal transition. BMC Genomics. 1-15.
    94. LncRNA NBR2 engages a metabolic checkpoint by regulating AMPK under energy stress. Nature Cell Biology.
    95. Obtaining reliable information from minute amounts of RNA using cDNA microarrays. BMC Genomics. 3.
    96. VEGFR-1 pseudogene expression and regulatory function in human colorectal cancer cells. Molecular Cancer Research. 13:1274-1282.
    97. Circulating microRNAs in pancreatic juice as candidate biomarkers of pancreatic cancer. Journal of Cancer. 5:696-705.
    98. Traumatic brain injury. Science Translational Medicine. 4.
    99. Genes suppressed by DNA methylation in non-small cell lung cancer reveal the epigenetics of epithelial-mesenchymal transition. BMC Genomics. 15.
    100. SUMOylation of HP1α supports association with ncRNA to define responsiveness of breast cancer cells to chemotherapy. Oncotarget. 7:30336-30349.
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