Header Logo

GE ZHOU

TitleAssistant Professor
InstitutionMD Anderson
DepartmentHead & Neck Surgery
Address1515 Holcombe Blvd
Houston TX 77030-4009
vCardDownload vCard

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Zhao M, Wang T, Gleber-Netto FO, Chen Z, McGrail DJ, Gomez JA, Ju W, Gadhikar MA, Ma W, Shen L, Wang Q, Tang X, Pathak S, Raso MG, Burks JK, Lin SY, Wang J, Multani AS, Pickering CR, Chen J, Myers JN, Zhou G. Mutant p53 gains oncogenic functions through a chromosomal instability-induced cytosolic DNA response. Nat Commun. 2024 Jan 02; 15(1):180. PMID: 38167338; PMCID: PMC10761733.
      Citations: 1     Fields:    Translation:Humans
    2. Zhang C, Smith MP, Zhou GK, Lai A, Hoy RC, Mroz V, Torre OM, Laudier DM, Bradley EW, Westendorf JJ, Iatridis JC, Illien-J?nger S. Phlpp1 is associated with human intervertebral disc degeneration and its deficiency promotes healing after needle puncture injury in mice. Cell Death Dis. 2019 10 03; 10(10):754. PMID: 31582730; PMCID: PMC6776553.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    3. Tanaka N, Zhao M, Tang L, Patel AA, Xi Q, Van HT, Takahashi H, Osman AA, Zhang J, Wang J, Myers JN, Zhou G. Gain-of-function mutant p53 promotes the oncogenic potential of head and neck squamous cell carcinoma cells by targeting the transcription factors FOXO3a and FOXM1. Oncogene. 2018 03; 37(10):1279-1292. PMID: 29269868; PMCID: PMC5844800.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    4. Zhou G, Liu Z, Myers JN. TP53 Mutations in Head and Neck Squamous Cell Carcinoma and Their Impact on Disease Progression and Treatment Response. J Cell Biochem. 2016 12; 117(12):2682-2692. PMID: 27166782; PMCID: PMC5493146.
      Citations: 103     Fields:    Translation:Humans
    5. Liang J, Xu ZX, Ding Z, Lu Y, Yu Q, Werle KD, Zhou G, Park YY, Peng G, Gambello MJ, Mills GB. Myristoylation confers noncanonical AMPK functions in autophagy selectivity and mitochondrial surveillance. Nat Commun. 2015 Aug 14; 6:7926. PMID: 26272043.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    6. Tanaka N, Patel AA, Wang J, Frederick MJ, Kalu NN, Zhao M, Fitzgerald AL, Xie TX, Silver NL, Caulin C, Zhou G, Skinner HD, Johnson FM, Myers JN, Osman AA. Wee-1 Kinase Inhibition Sensitizes High-Risk HPV+ HNSCC to Apoptosis Accompanied by Downregulation of MCl-1 and XIAP Antiapoptotic Proteins. Clin Cancer Res. 2015 Nov 01; 21(21):4831-44. PMID: 26124202; PMCID: PMC4631620.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    7. Zhou G, Myers JN. Mutant p53 exerts oncogenic functions by modulating cancer cell metabolism. Mol Cell Oncol. 2014 Jul-Sep; 1(3):e963441. PMID: 27308343; PMCID: PMC4904903.
      Citations: 3     
    8. Zhou G, Wang J, Zhao M, Xie TX, Tanaka N, Sano D, Patel AA, Ward AM, Sandulache VC, Jasser SA, Skinner HD, Fitzgerald AL, Osman AA, Wei Y, Xia X, Songyang Z, Mills GB, Hung MC, Caulin C, Liang J, Myers JN. Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation. Mol Cell. 2014 Jun 19; 54(6):960-974. PMID: 24857548; PMCID: PMC4067806.
      Citations: 119     Fields:    Translation:HumansAnimalsCells
    9. Ren G, Hu J, Wang R, Han W, Zhao M, Zhou G, Zhang C, Zhang Z. Rapamycin inhibits Toll-like receptor 4-induced pro-oncogenic function in head and neck squamous cell carcinoma. Oncol Rep. 2014 Jun; 31(6):2804-10. PMID: 24737049.
      Citations: 6     Fields:    Translation:HumansCells
    10. Henderson YC, Toro-Serra R, Chen Y, Ryu J, Frederick MJ, Zhou G, Gallick GE, Lai SY, Clayman GL. Src inhibitors in suppression of papillary thyroid carcinoma growth. Head Neck. 2014 Mar; 36(3):375-84. PMID: 23729178; PMCID: PMC4401074.
      Citations: 11     Fields:    Translation:AnimalsCells
    11. Xie TX, Zhou G, Zhao M, Sano D, Jasser SA, Brennan RG, Myers JN. Serine substitution of proline at codon 151 of TP53 confers gain of function activity leading to anoikis resistance and tumor progression of head and neck cancer cells. Laryngoscope. 2013 Jun; 123(6):1416-23. PMID: 23625637; PMCID: PMC3664100.
      Citations: 11     Fields:    Translation:AnimalsCells
    12. Sano D, Berlin JM, Pham TT, Marcano DC, Valdecanas DR, Zhou G, Milas L, Myers JN, Tour JM. Noncovalent assembly of targeted carbon nanovectors enables synergistic drug and radiation cancer therapy in vivo. ACS Nano. 2012 Mar 27; 6(3):2497-505. PMID: 22316245; PMCID: PMC3314092.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    13. Sano D, Xie TX, Ow TJ, Zhao M, Pickering CR, Zhou G, Sandulache VC, Wheeler DA, Gibbs RA, Caulin C, Myers JN. Disruptive TP53 mutation is associated with aggressive disease characteristics in an orthotopic murine model of oral tongue cancer. Clin Cancer Res. 2011 Nov 01; 17(21):6658-70. PMID: 21903770; PMCID: PMC3207013.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    14. Sandulache VC, Skinner HD, Ow TJ, Zhang A, Xia X, Luchak JM, Wong LJ, Pickering CR, Zhou G, Myers JN. Individualizing antimetabolic treatment strategies for head and neck squamous cell carcinoma based on TP53 mutational status. Cancer. 2012 Feb 01; 118(3):711-21. PMID: 21720999; PMCID: PMC3188683.
      Citations: 28     Fields:    Translation:HumansCells
    15. Gule MK, Chen Y, Sano D, Frederick MJ, Zhou G, Zhao M, Milas ZL, Galer CE, Henderson YC, Jasser SA, Schwartz DL, Bankson JA, Myers JN, Lai SY. Targeted therapy of VEGFR2 and EGFR significantly inhibits growth of anaplastic thyroid cancer in an orthotopic murine model. Clin Cancer Res. 2011 Apr 15; 17(8):2281-91. PMID: 21220477; PMCID: PMC3079006.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    16. Sandulache VC, Ow TJ, Pickering CR, Frederick MJ, Zhou G, Fokt I, Davis-Malesevich M, Priebe W, Myers JN. Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells. Cancer. 2011 Jul 01; 117(13):2926-38. PMID: 21692052; PMCID: PMC3135768.
      Citations: 64     Fields:    Translation:HumansCells
    17. Kupferman ME, Jiffar T, El-Naggar A, Yilmaz T, Zhou G, Xie T, Feng L, Wang J, Holsinger FC, Yu D, Myers JN. TrkB induces EMT and has a key role in invasion of head and neck squamous cell carcinoma. Oncogene. 2010 Apr 08; 29(14):2047-59. PMID: 20101235; PMCID: PMC3138334.
      Citations: 97     Fields:    Translation:HumansAnimalsCells
    18. Sano D, Choi S, Milas ZL, Zhou G, Galer CE, Su YW, Gule M, Zhao M, Zhu Z, Myers JN. The effect of combination anti-endothelial growth factor receptor and anti-vascular endothelial growth factor receptor 2 targeted therapy on lymph node metastasis: a study in an orthotopic nude mouse model of squamous cell carcinoma of the oral tongue. Arch Otolaryngol Head Neck Surg. 2009 Apr; 135(4):411-20. PMID: 19380367; PMCID: PMC2914603.
      Citations: 13     Fields:    Translation:Animals
    19. Kupferman ME, Jayakumar A, Zhou G, Xie T, Dakak-Yazici Y, Zhao M, Ju J, Mandal M, Jasser S, Madden T, Myers JN, Priebe W. Therapeutic suppression of constitutive and inducible JAK\STAT activation in head and neck squamous cell carcinoma. J Exp Ther Oncol. 2009; 8(2):117-27. PMID: 20192118.
      Citations: 15     Fields:    Translation:AnimalsCells
    20. Zhou G, Xie TX, Zhao M, Jasser SA, Younes MN, Sano D, Lin J, Kupferman ME, Santillan AA, Patel V, Gutkind JS, Ei-Naggar AK, Emberley ED, Watson PH, Matsuzawa SI, Reed JC, Myers JN. Reciprocal negative regulation between S100A7/psoriasin and beta-catenin signaling plays an important role in tumor progression of squamous cell carcinoma of oral cavity. Oncogene. 2008 Jun 05; 27(25):3527-38. PMID: 18223693.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    21. Gaultier A, Arandjelovic S, Li X, Janes J, Dragojlovic N, Zhou GP, Dolkas J, Myers RR, Gonias SL, Campana WM. A shed form of LDL receptor-related protein-1 regulates peripheral nerve injury and neuropathic pain in rodents. J Clin Invest. 2008 Jan; 118(1):161-72. PMID: 18060043; PMCID: PMC2104478.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    22. Kupferman ME, Patel V, Sriuranpong V, Amornphimoltham P, Jasser SA, Mandal M, Zhou G, Wang J, Coombes K, Multani A, Pathak S, Silvio Gutkind J, Myers JN. Molecular analysis of anoikis resistance in oral cavity squamous cell carcinoma. Oral Oncol. 2007 May; 43(5):440-54. PMID: 16978912.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    23. Park YW, Younes MN, Jasser SA, Yigitbasi OG, Zhou G, Bucana CD, Bekele BN, Myers JN. AEE788, a dual tyrosine kinase receptor inhibitor, induces endothelial cell apoptosis in human cutaneous squamous cell carcinoma xenografts in nude mice. Clin Cancer Res. 2005 Mar 01; 11(5):1963-73. PMID: 15756022.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    24. Schiff BA, McMurphy AB, Jasser SA, Younes MN, Doan D, Yigitbasi OG, Kim S, Zhou G, Mandal M, Bekele BN, Holsinger FC, Sherman SI, Yeung SC, El-Naggar AK, Myers JN. Epidermal growth factor receptor (EGFR) is overexpressed in anaplastic thyroid cancer, and the EGFR inhibitor gefitinib inhibits the growth of anaplastic thyroid cancer. Clin Cancer Res. 2004 Dec 15; 10(24):8594-602. PMID: 15623643.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    25. Zhou G, Hashimoto Y, Kwak I, Tsai SY, Tsai MJ. Role of the steroid receptor coactivator SRC-3 in cell growth. Mol Cell Biol. 2003 Nov; 23(21):7742-55. PMID: 14560019; PMCID: PMC207585.
      Citations: 58     Fields:    Translation:AnimalsCells
    26. Pereira FA, Qiu Y, Zhou G, Tsai MJ, Tsai SY. The orphan nuclear receptor COUP-TFII is required for angiogenesis and heart development. Genes Dev. 1999 Apr 15; 13(8):1037-49. PMID: 10215630; PMCID: PMC316637.
      Citations: 188     Fields:    Translation:Animals
    27. Zhou G, Kuo MT. Wild-type p53-mediated induction of rat mdr1b expression by the anticancer drug daunorubicin. J Biol Chem. 1998 Jun 19; 273(25):15387-94. PMID: 9624121.
      Citations: 12     Fields:    Translation:AnimalsCells
    28. Zhou G, Kuo MT. NF-kappaB-mediated induction of mdr1b expression by insulin in rat hepatoma cells. J Biol Chem. 1997 Jun 13; 272(24):15174-83. PMID: 9182539.
      Citations: 29     Fields:    Translation:AnimalsCells
    29. Zhou G, Song R, Kuo MT. A novel cis-acting element is involved in the promoter activity of the rat mdr1b gene. Cell Growth Differ. 1996 Oct; 7(10):1369-81. PMID: 8891341.
      Citations: 1     Fields:    Translation:AnimalsCells
    30. Song R, Ikeguchi M, Zhou G, Kuo MT. Identification and characterization of a hepatoma cell-specific enhancer in the mouse multidrug resistance mdr1b promoter. J Biol Chem. 1995 Oct 27; 270(43):25468-74. PMID: 7592715.
      Citations: 8     Fields:    Translation:AnimalsCells
    31. Wnt/β-catenin signaling and oral cancer metastasis. 231-264.
    32. Wee-1 kinase inhibition sensitizes high-risk HPV+ HNSCC to apoptosis accompanied by downregulation of MCl-1 and XIAP antiapoptotic proteins. Clinical Cancer Research. 21:4831-4844.
    33. Myristoylation confers noncanonical AMPK functions in autophagy selectivity and mitochondrial surveillance. Nature Communications. 6.
    ZHOU's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (261)
    Explore
    _
    Co-Authors (35)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _