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MICHAEL ROBERTSON

TitleAdjunct Assistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Biochemistry and Molecular Pharmacology
AddressOne Baylor Plaza
Houston, 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Koch TL, Yeung HY, Ramiro IBL, Torres JP, Vo AA, Palomino S, Engholm E, Robinson SD, Rash LD, Acyatan ZG, Schumann NC, Pedersen KB, Jensen KJ, Schjoldager KT, Patwardhan A, Young ND, Robertson MJ, Safavi-Hemami H. Mimics of the chordate gut-brain hormone neurotensin in parasitic intestinal hookworms. Curr Biol. 2026 08 17; 36(16):4124-4135.e8. PMID: 42551435.
      Citations:    
    2. Gomez JL, Ventriglia EN, Frangos ZJ, Sulima A, Robertson MJ, Sacco MD, Budinich RC, Giosan IM, Xie T, Solis O, Tischer AE, Bossert JM, Caldwell KE, Bonbrest H, Essmann A, Gar?on-Poca ZM, Choi S, Noya MR, Limiac F, Arce A, Glatfelter GC, Robinson M, Chen L, Mullarkey AA, Brademan DR, Enten G, Dunne W, Quiroz C, Schoenborn I, Lee CB, Rais R, Holt DP, Dannals RF, Shi L, H?ttenhain R, Ferr? S, Kiyatkin E, Bonaventura J, Shaham Y, Zachariou V, Baumann MH, Skiniotis G, Rice KC, Michaelides M. Author Correction: A ?-opioid receptor superagonist analgesic with minimal adverse effects. Nature. 2026 May; 653(8114):E4. PMID: 42032332; PMCID: PMC13171620.
      Citations:    Fields:    
    3. Gomez JL, Ventriglia EN, Frangos ZJ, Sulima A, Robertson MJ, Sacco MD, Budinich RC, Giosan IM, Xie T, Solis O, Tischer AE, Bossert JM, Caldwell KE, Bonbrest H, Essmann A, Gar?on-Poca ZM, Choi S, Noya MR, Limiac F, Arce A, Glatfelter GC, Robinson M, Chen L, Mullarkey AA, Brademan DR, Enten G, Dunne W, Quiroz C, Schoenborn I, Lee CB, Rais R, Holt DP, Dannals RF, Shi L, H?ttenhain R, Ferr? S, Kiyatkin E, Bonaventura J, Shaham Y, Zachariou V, Baumann MH, Skiniotis G, Rice KC, Michaelides M. A ?-opioid receptor superagonist analgesic with minimal adverse effects. Nature. 2026 Apr; 652(8112):1393-1404. PMID: 41922775; PMCID: PMC13128446.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    4. Vo AA, Modak A, Lu S, Blanchard SC, Lambert NA, Robertson MJ. Snapshots of the dynamic basis of NTSR1 G protein subtype promiscuity. Nature. 2026 04; 652(8110):803-811. PMID: 41813894; PMCID: PMC13083256.
      Citations: 1     Fields:    Translation:HumansCells
    5. Vo A, Sun YE, English JG, Robertson MJ. Designing Rigid Protein Fiducials to Visualize GPCR Conformational States. bioRxiv. 2026 Jan 26. PMID: 41659557; PMCID: PMC12873965.
      Citations:    
    6. Robertson MJ, Modak A, Papasergi-Scott MM, Hu M, Peroto MC, Varga BR, Majumdar S, Kalathur R, Blanchard SC, Skiniotis G. Non-equilibrium snapshots of ligand efficacy at the ?-opioid receptor. Nature. 2026 04; 652(8110):794-802. PMID: 41430437; PMCID: PMC13378529.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    7. Shub L, Liu W, Skiniotis G, Keiser MJ, Robertson MJ. MIC: A deep learning tool for assigning ions and waters in cryo-EM and crystal structures. Nat Commun. 2025 Jul 04; 16(1):6182. PMID: 40615379; PMCID: PMC12227754.
      Citations: 4     Fields:    
    8. Robertson MJ, Papasergi-Scott MM, Peroto MC, Varga BR, Majumdar S, Skiniotis G. Non-Equilibrium Snapshots of Ligand Efficacy at the ?-Opioid Receptor. bioRxiv. 2025 May 30. PMID: 40502042; PMCID: PMC12154725.
      Citations:    
    9. Clayton J, Shi L, Robertson MJ, Skiniotis G, Michaelides M, Stavitskaya L, Shen J. A putative binding model of nitazene derivatives at the ?-opioid receptor. Neuropharmacology. 2025 08 01; 273:110437. PMID: 40185362; PMCID: PMC12279083.
      Citations: 1     Fields:    Translation:HumansCells
    10. Clayton J, Shi L, Robertson MJ, Skiniotis G, Michaelides M, Stavitskaya L, Shen J. A Putative Binding Model of Nitazene Derivatives at the ?-Opioid Receptor. bioRxiv. 2025 Feb 11. PMID: 39990498; PMCID: PMC11844390.
      Citations:    
    11. Robertson MC, Swartz MC, Basen-Engquist KM, Li Y, Jennings K, Thompson D, Baranowski T, Volpi E, Lyons EJ. A social media game to increase physical activity among older adult women: protocol of a randomized controlled trial to evaluate CHALLENGE. BMC Public Health. 2024 08 12; 24(1):2172. PMID: 39135010; PMCID: PMC11318238.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    12. He F, Wu CG, Gao Y, Rahman SN, Zaoralov? M, Papasergi-Scott MM, Gu TJ, Robertson MJ, Seven AB, Li L, Mathiesen JM, Skiniotis G. Allosteric modulation and G-protein selectivity of the Ca2+-sensing receptor. Nature. 2024 02; 626(8001):1141-1148. PMID: 38326620; PMCID: PMC11929605.
      Citations: 25     Fields:    Translation:HumansCells
    13. Vizurraga AL, Robertson MJ, Yu M, Skiniotis G, Tall GG. Hexahydroquinoline Derivatives Are Selective Agonists for the Adhesion G Protein-Coupled Receptor ADGRG1/GPR56. Mol Pharmacol. 2023 07; 104(1):28-41. PMID: 37290962; PMCID: PMC10289240.
      Citations:    
    14. Krishna Kumar K, Robertson MJ, Thadhani E, Wang H, Suomivuori CM, Powers AS, Ji L, Nikas SP, Dror RO, Inoue A, Makriyannis A, Skiniotis G, Kobilka B. Structural basis for activation of CB1 by an endocannabinoid analog. Nat Commun. 2023 05 09; 14(1):2672. PMID: 37160876; PMCID: PMC10169858.
      Citations:    
    15. Lee CY, Robertson MC, Johnston H, Le T, Raber M, Rechis R, Oestman K, Neff A, Macneish A, Basen-Engquist KM. Feasibility and Effectiveness of a Worksite-Weight-Loss Program for Cancer Prevention among School-District Employees with Overweight and Obesity. Int J Environ Res Public Health. 2022 12 29; 20(1). PMID: 36612860; PMCID: PMC9819872.
      Citations: 2     Fields:    Translation:Humans
    16. Lee CY, Robertson MC, Servino K, Le T, Raber M, Oestman K, Basen-Engquist KM. Impact of COVID-19 on a worksite weight loss program for employees with overweight and obesity. Obes Sci Pract. 2022 Dec 21. PMID: 36718199; PMCID: PMC9877790.
      Citations: 1     
    17. Faouzi A, Wang H, Zaidi SA, DiBerto JF, Che T, Qu Q, Robertson MJ, Madasu MK, El Daibani A, Varga BR, Zhang T, Ruiz C, Liu S, Xu J, Appourchaux K, Slocum ST, Eans SO, Cameron MD, Al-Hasani R, Pan YX, Roth BL, McLaughlin JP, Skiniotis G, Katritch V, Kobilka BK, Majumdar S. Structure-based design of bitopic ligands for the ?-opioid receptor. Nature. 2023 01; 613(7945):767-774. PMID: 36450356; PMCID: PMC10328120.
      Citations:    
    18. Qu Q, Huang W, Aydin D, Paggi JM, Seven AB, Wang H, Chakraborty S, Che T, DiBerto JF, Robertson MJ, Inoue A, Suomivuori CM, Roth BL, Majumdar S, Dror RO, Kobilka BK, Skiniotis G. Insights into distinct signaling profiles of the ?OR activated by diverse agonists. Nat Chem Biol. 2023 04; 19(4):423-430. PMID: 36411392; PMCID: PMC11098091.
      Citations:    
    19. Robertson MJ, Papasergi-Scott MM, He F, Seven AB, Meyerowitz JG, Panova O, Peroto MC, Che T, Skiniotis G. Structure determination of inactive-state GPCRs with a universal nanobody. Nat Struct Mol Biol. 2022 12; 29(12):1188-1195. PMID: 36396979; PMCID: PMC12014012.
      Citations:    
    20. Kaplan AL, Confair DN, Kim K, Barros-?lvarez X, Rodriguiz RM, Yang Y, Kweon OS, Che T, McCorvy JD, Kamber DN, Phelan JP, Martins LC, Pogorelov VM, DiBerto JF, Slocum ST, Huang XP, Kumar JM, Robertson MJ, Panova O, Seven AB, Wetsel AQ, Wetsel WC, Irwin JJ, Skiniotis G, Shoichet BK, Roth BL, Ellman JA. Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity. Nature. 2022 10; 610(7932):582-591. PMID: 36171289; PMCID: PMC9996387.
      Citations:    
    21. Liao Y, Robertson MC, O'Connor SG, Naya CH, Balachandran DD, Dunton GF. Exploring the Effects of Perceived Stress on the Within-Person Relationships Between Daily Activity Levels and Sleep in Women: An Ecological Momentary Assessment Study. Int J Behav Med. 2023 Aug; 30(4):578-583. PMID: 36161390.
      Citations:    Fields:    Translation:Humans
    22. Cao C, Barros-?lvarez X, Zhang S, Kim K, D?mgen MA, Panova O, Suomivuori CM, Fay JF, Zhong X, Krumm BE, Gumpper RH, Seven AB, Robertson MJ, Krogan NJ, H?ttenhain R, Nichols DE, Dror RO, Skiniotis G, Roth BL. Signaling snapshots of a serotonin receptor activated by the prototypical psychedelic LSD. Neuron. 2022 Oct 05; 110(19):3154-3167.e7. PMID: 36087581; PMCID: PMC9583076.
      Citations:    
    23. Chen G, Wang X, Liao Q, Ge Y, Jiao H, Chen Q, Liu Y, Lyu W, Zhu L, van Zundert GCP, Robertson MJ, Skiniotis G, Du Y, Hu H, Ye RD. Structural basis for recognition of N-formyl peptides as pathogen-associated molecular patterns. Nat Commun. 2022 09 05; 13(1):5232. PMID: 36064945; PMCID: PMC9445081.
      Citations:    
    24. Robertson MJ, Meyerowitz JG, Panova O, Borrelli K, Skiniotis G. Author Correction: Plasticity in ligand recognition at somatostatin receptors. Nat Struct Mol Biol. 2022 Aug; 29(8):841. PMID: 35804245.
      Citations:    
    25. Robertson MJ, Skiniotis G. Development of OPLS-AA/M Parameters for Simulations of G Protein-Coupled Receptors and Other Membrane Proteins. J Chem Theory Comput. 2022 Jul 12; 18(7):4482-4489. PMID: 35687850.
      Citations:    
    26. Robertson MC, Swartz MC, Christopherson U, Bentley JR, Basen-Engquist KM, Thompson D, Volpi E, Lyons EJ. A Photography-based, Social Media Walking Intervention Targeting Autonomous Motivations for Physical Activity: Semistructured Interviews With Older Women. JMIR Serious Games. 2022 Apr 14; 10(2):e35511. PMID: 35436205; PMCID: PMC9052025.
      Citations: 3     
    27. Barros-?lvarez X, Nwokonko RM, Vizurraga A, Matzov D, He F, Papasergi-Scott MM, Robertson MJ, Panova O, Yardeni EH, Seven AB, Kwarcinski FE, Su H, Peroto MC, Meyerowitz JG, Shalev-Benami M, Tall GG, Skiniotis G. The tethered peptide activation mechanism of adhesion GPCRs. Nature. 2022 04; 604(7907):757-762. PMID: 35418682; PMCID: PMC9841879.
      Citations:    
    28. Meyerowitz JG, Robertson MJ, Barros-?lvarez X, Panova O, Nwokonko RM, Gao Y, Skiniotis G. The oxytocin signaling complex reveals a molecular switch for cation dependence. Nat Struct Mol Biol. 2022 03; 29(3):274-281. PMID: 35241813; PMCID: PMC12101619.
      Citations:    
    29. Robertson MJ, Meyerowitz JG, Panova O, Borrelli K, Skiniotis G. Plasticity in ligand recognition at somatostatin receptors. Nat Struct Mol Biol. 2022 03; 29(3):210-217. PMID: 35210615; PMCID: PMC11073612.
      Citations:    
    30. Han L, Qu Q, Aydin D, Panova O, Robertson MJ, Xu Y, Dror RO, Skiniotis G, Feng L. Structure and mechanism of the SGLT family of glucose transporters. Nature. 2022 01; 601(7892):274-279. PMID: 34880492; PMCID: PMC9482448.
      Citations:    
    31. Robertson MC, Baranowski T, Thompson D, Basen-Engquist KM, Swartz MC, Lyons EJ. Using the Behaviour Change Wheel Program Planning Model to Design Games for Health: Development Study. JMIR Serious Games. 2021 Dec 03; 9(4):e29964. PMID: 34870604; PMCID: PMC8686484.
      Citations: 4     
    32. Robertson MC, Lee CY, Wu IH, Liao Y, Raber M, Parker N, Le T, Gatus L, Basen-Engquist KM. Changes in physical activity associated with the COVID-19 pandemic in individuals with overweight and obesity: an interrupted time series analysis with historical controls. J Behav Med. 2022 04; 45(2):186-196. PMID: 34698998; PMCID: PMC8546384.
      Citations: 5     Fields:    Translation:HumansPHPublic Health
    33. Mathiharan YK, Glaaser IW, Zhao Y, Robertson MJ, Skiniotis G, Slesinger PA. Structural insights into GIRK2 channel modulation by cholesterol and PIP2. Cell Rep. 2021 08 24; 36(8):109619. PMID: 34433062; PMCID: PMC8436891.
      Citations:    
    34. Robertson MC, Raber M, Liao Y, Wu I, Parker N, Gatus L, Le T, Durand CP, Basen-Engquist KM. Patterns of self-monitoring technology use and weight loss in people with overweight or obesity. Transl Behav Med. 2021 08 13; 11(8):1537-1547. PMID: 33837792; PMCID: PMC8604273.
      Citations: 10     Fields:    Translation:Humans
    35. Robertson MJ, Meyerowitz JG, Skiniotis G. Drug discovery in the era of cryo-electron microscopy. Trends Biochem Sci. 2022 02; 47(2):124-135. PMID: 34281791; PMCID: PMC8760134.
      Citations:    
    36. Seven AB, Barros-?lvarez X, de Lapeyri?re M, Papasergi-Scott MM, Robertson MJ, Zhang C, Nwokonko RM, Gao Y, Meyerowitz JG, Rocher JP, Schelshorn D, Kobilka BK, Mathiesen JM, Skiniotis G. G-protein activation by a metabotropic glutamate receptor. Nature. 2021 07; 595(7867):450-454. PMID: 34194039; PMCID: PMC8822903.
      Citations:    
    37. Gao Y, Robertson MJ, Rahman SN, Seven AB, Zhang C, Meyerowitz JG, Panova O, Hannan FM, Thakker RV, Br?uner-Osborne H, Mathiesen JM, Skiniotis G. Asymmetric activation of the calcium-sensing receptor homodimer. Nature. 2021 07; 595(7867):455-459. PMID: 34194040; PMCID: PMC8826748.
      Citations:    
    38. Kim K, Che T, Panova O, DiBerto JF, Lyu J, Krumm BE, Wacker D, Robertson MJ, Seven AB, Nichols DE, Shoichet BK, Skiniotis G, Roth BL. Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor. Cell. 2020 09 17; 182(6):1574-1588.e19. PMID: 32946782; PMCID: PMC7593816.
      Citations:    
    39. Papasergi-Scott MM, Robertson MJ, Seven AB, Panova O, Mathiesen JM, Skiniotis G. Structures of metabotropic GABAB receptor. Nature. 2020 08; 584(7820):310-314. PMID: 32580208; PMCID: PMC7429364.
      Citations:    
    40. Robertson MJ, van Zundert GCP, Borrelli K, Skiniotis G. GemSpot: A Pipeline for Robust Modeling of Ligands into Cryo-EM Maps. Structure. 2020 06 02; 28(6):707-716.e3. PMID: 32413291; PMCID: PMC7272260.
      Citations:    
    41. Huang W, Masureel M, Qu Q, Janetzko J, Inoue A, Kato HE, Robertson MJ, Nguyen KC, Glenn JS, Skiniotis G, Kobilka BK. Structure of the neurotensin receptor 1 in complex with ?-arrestin 1. Nature. 2020 03; 579(7798):303-308. PMID: 31945771; PMCID: PMC7100716.
      Citations:    
    42. Staus DP, Hu H, Robertson MJ, Kleinhenz ALW, Wingler LM, Capel WD, Latorraca NR, Lefkowitz RJ, Skiniotis G. Structure of the M2 muscarinic receptor-?-arrestin complex in a lipid nanodisc. Nature. 2020 03; 579(7798):297-302. PMID: 31945772; PMCID: PMC7367492.
      Citations:    
    43. Robertson MC, Lyons EJ, Song J, Cox-Martin M, Li Y, Green CE, Pinto BM, Carmack CL, Harrison C, Baum G, Basen-Engquist KM. Change in physical activity and quality of life in endometrial cancer survivors receiving a physical activity intervention. Health Qual Life Outcomes. 2019 May 27; 17(1):91. PMID: 31133040; PMCID: PMC6537149.
      Citations: 9     Fields:    Translation:Humans
    44. Maeda S, Qu Q, Robertson MJ, Skiniotis G, Kobilka BK. Structures of the M1 and M2 muscarinic acetylcholine receptor/G-protein complexes. Science. 2019 05 10; 364(6440):552-557. PMID: 31073061; PMCID: PMC7034192.
      Citations:    
    45. Koehl A, Hu H, Feng D, Sun B, Zhang Y, Robertson MJ, Chu M, Kobilka TS, Laeremans T, Steyaert J, Tarrasch J, Dutta S, Fonseca R, Weis WI, Mathiesen JM, Skiniotis G, Kobilka BK. Author Correction: Structural insights into the activation of metabotropic glutamate receptors. Nature. 2019 Mar; 567(7747):E10. PMID: 30814739.
      Citations:    
    46. Koehl A, Hu H, Feng D, Sun B, Zhang Y, Robertson MJ, Chu M, Kobilka TS, Laeremans T, Steyaert J, Tarrasch J, Dutta S, Fonseca R, Weis WI, Mathiesen JM, Skiniotis G, Kobilka BK. Structural insights into the activation of metabotropic glutamate receptors. Nature. 2019 02; 566(7742):79-84. PMID: 30675062; PMCID: PMC6709600.
      Citations:    
    47. Krishna Kumar K, Shalev-Benami M, Robertson MJ, Hu H, Banister SD, Hollingsworth SA, Latorraca NR, Kato HE, Hilger D, Maeda S, Weis WI, Farrens DL, Dror RO, Malhotra SV, Kobilka BK, Skiniotis G. Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex. Cell. 2019 01 24; 176(3):448-458.e12. PMID: 30639101; PMCID: PMC6461403.
      Citations:    
    48. Schembre SM, Liao Y, Robertson MC, Dunton GF, Kerr J, Haffey ME, Burnett T, Basen-Engquist K, Hicklen RS. Just-in-Time Feedback in Diet and Physical Activity Interventions: Systematic Review and Practical Design Framework. J Med Internet Res. 2018 03 22; 20(3):e106. PMID: 29567638; PMCID: PMC5887039.
      Citations: 43     Fields:    Translation:Humans
    49. Younes A, Pro B, Robertson MJ, Flinn IW, Romaguera JE, Hagemeister F, Dang NH, Fiumara P, Loyer EM, Cabanillas FF, McLaughlin PW, Rodriguez MA, Samaniego F. Phase II clinical trial of interleukin-12 in patients with relapsed and refractory non-Hodgkin's lymphoma and Hodgkin's disease. Clin Cancer Res. 2004 Aug 15; 10(16):5432-8. PMID: 15328181.
      Citations: 44     Fields:    Translation:HumansCTClinical Trials
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