PENGXIANG HUANG

AddressOne Baylor Plaza
Houston, TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Lin XD, Lin N, Lin TT, Wu YP, Huang P, Ke ZB, Lin YZ, Chen SH, Zheng QS, Wei Y, Xue XY, Lin RJ, Xu N. Identification of marker genes and cell subtypes in castration-resistant prostate cancer cells. J Cancer. 2021; 12(4):1249-1257. PMID: 33442423.
      Citations:    
    2. Han X, Zhang G, Li B, Yang C, Guo W, Bai X, Huang P, Chen R, Qin C, Hu J, Ma Y, Zhong H, Xiao L, Jia S. Blinking Mechanisms and Intrinsic Quantum-Confined Stark Effect in Single Methylammonium Lead Bromide Perovskite Quantum Dots. Small. 2020 Dec; 16(51):e2005435. PMID: 33236844.
      Citations:    Fields:    
    3. Liu Q, Hou J, Hao Q, Huang P, Xu C, Zhou Q, Zhou J, Liu H. Nitrogen-doped carbon encapsulated hollow ZnSe/CoSe2 nanospheres as high performance anodes for lithium-ion batteries. Nanoscale. 2020 Nov 19; 12(44):22778-22786. PMID: 33174569.
      Citations:    Fields:    
    4. Glorieux C, Xia X, He YQ, Hu Y, Cremer K, Robert A, Liu J, Wang F, Ling J, Chiao PJ, Huang P. Regulation of PD-L1 expression in K-ras-driven cancers through ROS-mediated FGFR1 signaling. Redox Biol. 2021 Jan; 38:101780. PMID: 33171331.
      Citations:    Fields:    
    5. Deng X, Huang P, Luo J, Wang J, Yi L, Yang G, He S, Li X, Xiang S. A novel three-dimensional printed vacuum bell for pectus excavatum treatment: a preliminary study. J Cardiothorac Surg. 2020 Sep 10; 15(1):240. PMID: 32912269.
      Citations:    Fields:    Translation:Humans
    6. Liu J, Xia X, Huang P. xCT: A Critical Molecule That Links Cancer Metabolism to Redox Signaling. Mol Ther. 2020 11 04; 28(11):2358-2366. PMID: 32931751.
      Citations:    Fields:    
    7. Liu X, Zhang Y, Lu W, Han Y, Yang J, Jiang W, You X, Luo Y, Wen S, Hu Y, Huang P. Mitochondrial TXNRD3 confers drug resistance via redox-mediated mechanism and is a potential therapeutic target in vivo. Redox Biol. 2020 09; 36:101652. PMID: 32750669.
      Citations: 1     Fields:    
    8. Li SB, Liu YY, Yuan L, Ji MF, Zhang A, Li HY, Tang LQ, Fang SG, Zhang H, Xing S, Li MZ, Zhong Q, Lin SJ, Liu WL, Huang P, Zeng YX, Zheng YM, Ling ZQ, Sui JH, Zeng MS. Autocrine INSL5 promotes tumor progression and glycolysis via activation of STAT5 signaling. EMBO Mol Med. 2020 09 07; 12(9):e12050. PMID: 32657028.
      Citations: 1     Fields:    
    9. Ke ZB, Wu YP, Huang P, Hou J, Chen YH, Dong RN, Lin F, Wei Y, Xue XY, Ng CF, Xu N. Identification of novel genes in testicular cancer microenvironment based on ESTIMATE algorithm-derived immune scores. J Cell Physiol. 2021 Jan; 236(1):706-713. PMID: 32617980.
      Citations:    Fields:    
    10. Wang H, Liang L, Guo Z, Peng H, Qiao S, Saha N, Zhu D, Zeng W, Chen Y, Huang P, Wen S. Highly Reactive Cyclic Monoaryl Iodoniums Tuned as Carbene Generators Couple with Nucleophiles under Metal-Free Conditions. iScience. 2020 Jul 24; 23(7):101307. PMID: 32634743.
      Citations:    
    11. Ji D, Zhong X, Huang P, Kang P, Leng K, Zheng W, Wang Z, Xu Y, Cui Y. Deoxyelephantopin induces apoptosis via oxidative stress and enhances gemcitabine sensitivity in vitro and in vivo through targeting the NF-?B signaling pathway in pancreatic cancer. Aging (Albany NY). 2020 06 11; 12(11):11116-11138. PMID: 32526702.
      Citations:    Fields:    
    12. Huang X, He C, Hua X, Kan A, Mao Y, Sun S, Duan F, Wang J, Huang P, Li S. Oxidative stress induces monocyte-to-myofibroblast transdifferentiation through p38 in pancreatic ductal adenocarcinoma. Clin Transl Med. 2020 Jun; 10(2):e41. PMID: 32508052.
      Citations:    
    13. Guo T, Shen Q, Guo W, He W, Li J, Zhang Y, Wang Y, Zhou Z, Deng D, Ouyang X, Xiang Z, Jiang M, Liang M, Huang P, Peng Z, Xiang X, Liu W, Luo H, Chen P, Peng H. Clinical Characteristics of Elderly Patients with COVID-19 in Hunan Province, China: A Multicenter, Retrospective Study. Gerontology. 2020; 66(5):467-475. PMID: 32474561.
      Citations: 10     Fields:    Translation:HumansCellsPHPublic Health
    14. Wang M, Zhao J, Wang Y, Mao Y, Zhao X, Huang P, Liu Q, Ma Y, Yao Y, Yang Z, Yuan W, Cui W, Payne TJ, Li MD. Genome-wide DNA methylation analysis reveals significant impact of long-term ambient air pollution exposure on biological functions related to mitochondria and immune response. Environ Pollut. 2020 Sep; 264:114707. PMID: 32388307.
      Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
    15. Huang P, Xu M, Wu Y, Rizvi Syeda AK, Dong XP. Multiple facets of TRPML1 in autophagy. Cell Calcium. 2020 Apr 27; 88:102196. PMID: 32380434.
      Citations:    Fields:    
    16. Liang L, Wang H, Du Y, Luo B, Meng N, Cen M, Huang P, Ganesan A, Wen S. New tranylcypromine derivatives containing sulfonamide motif as potent LSD1 inhibitors to target acute myeloid leukemia: Design, synthesis and biological evaluation. Bioorg Chem. 2020 06; 99:103808. PMID: 32334189.
      Citations:    Fields:    
    17. Liu X, Zhang Y, Han Y, Lu W, Yang J, Tian J, Sun P, Yu T, Hu Y, Zhang H, Huang P, Liu P. Overexpression of GLT1D1 induces immunosuppression through glycosylation of PD-L1 and predicts poor prognosis in B-cell lymphoma. Mol Oncol. 2020 05; 14(5):1028-1044. PMID: 32157792.
      Citations: 1     Fields:    
    18. Liu J, Liu ZX, Wu QN, Lu YX, Wong CW, Miao L, Wang Y, Wang Z, Jin Y, He MM, Ren C, Wang DS, Chen DL, Pu HY, Feng L, Li B, Xie D, Zeng MS, Huang P, Lin A, Lin D, Xu RH, Ju HQ. Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming. Nat Commun. 2020 03 20; 11(1):1507. PMID: 32198345.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    19. Xu S, Wu J, Huang P, Lao C, Lai H, Wang Y, Wang Z, Zhong G, Fu X, Peng F. Selective Catalytic Oxidation of Benzyl Alcohol to Benzaldehyde by Nitrates. Front Chem. 2020; 8:151. PMID: 32266207.
      Citations:    
    20. Meng N, Glorieux C, Zhang Y, Liang L, Zeng P, Lu W, Huang P. Oncogenic K-ras Induces Mitochondrial OPA3 Expression to Promote Energy Metabolism in Pancreatic Cancer Cells. Cancers (Basel). 2019 Dec 25; 12(1). PMID: 31881642.
      Citations:    
    21. Glorieux C, Huang P. CD137 expression in cancer cells: regulation and significance. Cancer Commun (Lond). 2019 11 08; 39(1):70. PMID: 31703738.
      Citations:    Fields:    Translation:HumansCells
    22. Huang S, Huang P, Wang L, Han J, Chen Y, Zhong H. Halogenated-Methylammonium Based 3D Halide Perovskites. . 2019 Oct; 31(42):e1903830. PMID: 31490605.
      Citations:    
    23. Wang Z, Chen J, Hu J, Zhang H, Xu F, He W, Wang X, Li M, Lu W, Zeng G, Zhou P, Huang P, Chen S, Li W, Xia LP, Xia X. cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity. J Clin Invest. 2019 08 13; 129(11):4850-4862. PMID: 31408442.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    24. Zhang Y, Xu R, Li X, Tan Q, Huang P, Zhang Y, Qin M, Ren L. Effects of icariin on long noncoding RNA and mRNA expression profile in the aortas of apoE-deficient mice. Biosci Rep. 2019 07 31; 39(7). PMID: 31296789.
      Citations:    Fields:    Translation:Animals
    25. Wang Z, Zhou L, Xiong Y, Yu S, Li H, Fan J, Li F, Su Z, Song J, Sun Q, Liu SS, Xia Y, Zhao L, Li S, Guo F, Huang P, Carson DA, Lu D. Salinomycin exerts anti-colorectal cancer activity by targeting the ß-catenin/T-cell factor complex. Br J Pharmacol. 2019 09; 176(17):3390-3406. PMID: 31236922.
      Citations:    Fields:    Translation:HumansAnimalsCells
    26. Glorieux C, Huang P. Regulation of CD137 expression through K-Ras signaling in pancreatic cancer cells. Cancer Commun (Lond). 2019 07 09; 39(1):41. PMID: 31288851.
      Citations: 1     Fields:    Translation:HumansCells
    27. Han Y, Chen P, Zhang Y, Lu W, Ding W, Luo Y, Wen S, Xu R, Liu P, Huang P. Synergy between Auranofin and Celecoxib against Colon Cancer In Vitro and In Vivo through a Novel Redox-Mediated Mechanism. Cancers (Basel). 2019 Jul 03; 11(7). PMID: 31277230.
      Citations:    
    28. Huang P, Liu XL, Leng YJ, Lu WB, Cai J, Zeng Q. [Qilin Pills improve sperm quality in patients with oligozoospermia]. Zhonghua Nan Ke Xue. 2019 Jul; 25(7):647-650. PMID: 32223108.
      Citations:    Fields:    Translation:HumansCells
    29. Lee HJ, Ehlerding EB, Jiang D, Barnhart TE, Cao T, Wei W, Ferreira CA, Huang P, Engle JW, Cai W. Dual-labeled pertuzumab for multimodality image-guided ovarian tumor resection. Am J Cancer Res. 2019; 9(7):1454-1468. PMID: 31392081.
      Citations:    
    30. Ju HQ, Lu YX, Chen DL, Zuo ZX, Liu ZX, Wu QN, Mo HY, Wang ZX, Wang DS, Pu HY, Zeng ZL, Li B, Xie D, Huang P, Hung MC, Chiao PJ, Xu RH. Modulation of Redox Homeostasis by Inhibition of MTHFD2 in Colorectal Cancer: Mechanisms and Therapeutic Implications. J Natl Cancer Inst. 2019 Jun 01; 111(6):584-596. PMID: 30534944.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    31. Huang P, Sun LY, Zhang YQ. A Hopeful Natural Product, Pristimerin, Induces Apoptosis, Cell Cycle Arrest, and Autophagy in Esophageal Cancer Cells. Anal Cell Pathol (Amst). 2019; 2019:6127169. PMID: 31218209.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    32. You X, Jiang W, Lu W, Zhang H, Yu T, Tian J, Wen S, Garcia-Manero G, Huang P, Hu Y. Metabolic reprogramming and redox adaptation in sorafenib-resistant leukemia cells: detected by untargeted metabolomics and stable isotope tracing analysis. Cancer Commun (Lond). 2019 04 04; 39(1):17. PMID: 30947742.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    33. Fu LH, Qi C, Hu YR, Lin J, Huang P. Glucose Oxidase-Instructed Multimodal Synergistic Cancer Therapy. . 2019 May; 31(21):e1808325. PMID: 30907460.
      Citations:    
    34. Zhang Y, Bo S, Feng T, Qin X, Wan Y, Jiang S, Li C, Lin J, Wang T, Zhou X, Jiang ZX, Huang P. A Versatile Theranostic Nanoemulsion for Architecture-Dependent Multimodal Imaging and Dually Augmented Photodynamic Therapy. . 2019 May; 31(21):e1806444. PMID: 30907469.
      Citations:    
    35. Dong T, Yang WM, Wu MC, Zhang J, Huang P, Xu CS, Wang AQ, Kuang CJ, Gao ZL. Microstructure changes in whiter matter relate to cognitive impairment in Wilson's disease. Biosci Rep. 2019 03 29; 39(3). PMID: 30804230.
      Citations: 1     Fields:    Translation:Humans
    36. Xu M, Almasi S, Yang Y, Yan C, Sterea AM, Rizvi Syeda AK, Shen B, Richard Derek C, Huang P, Gujar S, Wang J, Zong WX, Trebak M, El Hiani Y, Dong XP. The lysosomal TRPML1 channel regulates triple negative breast cancer development by promoting mTORC1 and purinergic signaling pathways. Cell Calcium. 2019 05; 79:80-88. PMID: 30889511.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    37. Cui B, Luo Y, Tian P, Peng F, Lu J, Yang Y, Su Q, Liu B, Yu J, Luo X, Yin L, Cheng W, An F, He B, Liang D, Wu S, Chu P, Song L, Liu X, Luo H, Xu J, Pan Y, Wang Y, Li D, Huang P, Yang Q, Zhang L, Zhou BP, Liu S, Xu G, Lam EW, Kelley KW, Liu Q. Stress-induced epinephrine enhances lactate dehydrogenase A and promotes breast cancer stem-like cells. J Clin Invest. 2019 03 01; 129(3):1030-1046. PMID: 30688660.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    38. Huang Z, Zhao ZJ, Zhang Q, Han L, Jiang X, Li C, Cardenas MTP, Huang P, Yin JJ, Luo J, Gong J, Nie Z. A welding phenomenon of dissimilar nanoparticles in dispersion. Nat Commun. 2019 01 15; 10(1):219. PMID: 30644406.
      Citations: 1     Fields:    
    39. Ehlerding EB, Lee HJ, Jiang D, Ferreira CA, Zahm CD, Huang P, Engle JW, McNeel DG, Cai W. Antibody and fragment-based PET imaging of CTLA-4+ T-cells in humanized mouse models. Am J Cancer Res. 2019; 9(1):53-63. PMID: 30755811.
      Citations:    
    40. Guo ZL, Li JZ, Ma YY, Qian D, Zhong JY, Jin MM, Huang P, Che LY, Pan B, Wang Y, Sun ZX, Liu CZ. Shikonin sensitizes A549 cells to TRAIL-induced apoptosis through the JNK, STAT3 and AKT pathways. BMC Cell Biol. 2018 12 29; 19(1):29. PMID: 30594131.
      Citations: 3     Fields:    Translation:HumansCells
    41. Huang P, Ouyang DJ, Chang S, Li MY, Li L, Li QY, Zeng R, Zou QY, Su J, Zhao P, Pei L, Yi WJ. Chemotherapy-driven increases in the CDKN1A/PTN/PTPRZ1 axis promote chemoresistance by activating the NF-?B pathway in breast cancer cells. Cell Commun Signal. 2018 11 29; 16(1):92. PMID: 30497491.
      Citations: 3     Fields:    Translation:HumansCells
    42. Jiang S, Eberhart CG, Lim M, Heo HY, Zhang Y, Blair L, Wen Z, Holdhoff M, Lin D, Huang P, Qin H, Quinones-Hinojosa A, Weingart JD, Barker PB, Pomper MG, Laterra J, van Zijl PCM, Blakeley JO, Zhou J. Identifying Recurrent Malignant Glioma after Treatment Using Amide Proton Transfer-Weighted MR Imaging: A Validation Study with Image-Guided Stereotactic Biopsy. Clin Cancer Res. 2019 01 15; 25(2):552-561. PMID: 30366937.
      Citations: 12     Fields:    Translation:Humans
    43. Zhang Y, Shi J, Liu X, Feng L, Gong Z, Koppula P, Sirohi K, Li X, Wei Y, Lee H, Zhuang L, Chen G, Xiao ZD, Hung MC, Chen J, Huang P, Li W, Gan B. BAP1 links metabolic regulation of ferroptosis to tumour suppression. Nat Cell Biol. 2018 10; 20(10):1181-1192. PMID: 30202049.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    44. Li Y, Sui H, Jiang C, Li S, Han Y, Huang P, Du X, Du J, Bai Y. Dihydroartemisinin Increases the Sensitivity of Photodynamic Therapy Via NF-?B/HIF-1a/VEGF Pathway in Esophageal Cancer Cell in vitro and in vivo. Cell Physiol Biochem. 2018; 48(5):2035-2045. PMID: 30099443.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    45. Zhang X, Wang J, Chen Z, Hu Q, Wang C, Yan J, Dotti G, Huang P, Gu Z. Engineering PD-1-Presenting Platelets for Cancer Immunotherapy. . 2018 09 12; 18(9):5716-5725. PMID: 30063143.
      Citations:    
    46. Zhu D, Wu Z, Luo B, Du Y, Liu P, Chen Y, Hu Y, Huang P, Wen S. Heterocyclic Iodoniums for the Assembly of Oxygen-Bridged Polycyclic Heteroarenes with Water as the Oxygen Source. Org Lett. 2018 08 17; 20(16):4815-4818. PMID: 30052461.
      Citations: 1     Fields:    
    47. Li X, Luo J, Deng H, Huang P, Ge C, Yu H, Xu W. Effect of cassava waste biochar on sorption and release behavior of atrazine in soil. Sci Total Environ. 2018 Dec 10; 644:1617-1624. PMID: 30743874.
      Citations:    Fields:    Translation:AnimalsPHPublic Health
    48. Lam-Ubol A, Fitzgerald AL, Ritdej A, Phonyiam T, Zhang H, Myers JN, Huang P, Trachootham D. Sensory acceptable equivalent doses of ß-phenylethyl isothiocyanate (PEITC) induce cell cycle arrest and retard the growth of p53 mutated oral cancer in vitro and in vivo. Food Funct. 2018 Jul 17; 9(7):3640-3656. PMID: 29923573.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    49. Wang YN, Zeng ZL, Lu J, Wang Y, Liu ZX, He MM, Zhao Q, Wang ZX, Li T, Lu YX, Wu QN, Yu K, Wang F, Pu HY, Li B, Jia WH, Shi M, Xie D, Kang TB, Huang P, Ju HQ, Xu RH. CPT1A-mediated fatty acid oxidation promotes colorectal cancer cell metastasis by inhibiting anoikis. Oncogene. 2018 11; 37(46):6025-6040. PMID: 29995871.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    50. Li Y, Lin S, Li L, Tang Z, Hu Y, Ban X, Zeng T, Zhou Y, Zhu Y, Gao S, Deng W, Zhang X, Xie D, Yuan Y, Huang P, Li J, Cai Z, Guan XY. PDSS2 Deficiency Induces Hepatocarcinogenesis by Decreasing Mitochondrial Respiration and Reprogramming Glucose Metabolism. Cancer Res. 2018 08 15; 78(16):4471-4481. PMID: 29967258.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    51. Sun Y, Jiang W, Lu W, Song M, Liu K, Chen P, Chang A, Ling J, Chiao PJ, Hu Y, Huang P. Identification of cisplatin sensitizers through high-throughput combinatorial screening. Int J Oncol. 2018 Sep; 53(3):1237-1246. PMID: 29956742.
      Citations: 2     Fields:    Translation:HumansCells
    52. Liu J, Chen G, Liu Z, Liu S, Cai Z, You P, Ke Y, Lai L, Huang Y, Gao H, Zhao L, Pelicano H, Huang P, McKeehan WL, Wu CL, Wang C, Zhong W, Wang F. Aberrant FGFR Tyrosine Kinase Signaling Enhances the Warburg Effect by Reprogramming LDH Isoform Expression and Activity in Prostate Cancer. Cancer Res. 2018 08 15; 78(16):4459-4470. PMID: 29891507.
      Citations: 15     Fields:    Translation:HumansCells
    53. Postovit L, Widmann C, Huang P, Gibson SB. Harnessing Oxidative Stress as an Innovative Target for Cancer Therapy. Oxid Med Cell Longev. 2018; 2018:6135739. PMID: 29977457.
      Citations: 7     Fields:    Translation:Humans
    54. Luo J, Li X, Ge C, Müller K, Yu H, Huang P, Li J, Tsang DCW, Bolan NS, Rinklebe J, Wang H. Sorption of norfloxacin, sulfamerazine and oxytetracycline by KOH-modified biochar under single and ternary systems. Bioresour Technol. 2018 Sep; 263:385-392. PMID: 29763802.
      Citations: 4     Fields:    Translation:CellsPHPublic Health
    55. Shao J, Glorieux C, Liao J, Chen P, Lu W, Liang Z, Wen S, Hu Y, Huang P. Impact of Nrf2 on tumour growth and drug sensitivity in oncogenic K-ras-transformed cells in vitro and in vivo. Free Radic Res. 2018 Jun; 52(6):661-671. PMID: 29621903.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    56. Huang P, Sun Q, Shi W, Du W, Li X, Zhang N. Efficient production of human goose-type lysozyme 2 in the methylotrophic yeast Pichia pastoris. J Biotechnol. 2018 Jun 10; 275:44-52. PMID: 29660471.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    57. Huang P, Mao LF, Zhang ZP, Lv WW, Feng XP, Liao HJ, Dong C, Kaluba B, Tang XF, Chang S. Down-Regulated miR-125a-5p Promotes the Reprogramming of Glucose Metabolism and Cell Malignancy by Increasing Levels of CD147 in Thyroid Cancer. Thyroid. 2018 05; 28(5):613-623. PMID: 29634399.
      Citations: 14     Fields:    Translation:HumansCells
    58. Cascone T, McKenzie JA, Mbofung RM, Punt S, Wang Z, Xu C, Williams LJ, Wang Z, Bristow CA, Carugo A, Peoples MD, Li L, Karpinets T, Huang L, Malu S, Creasy C, Leahey SE, Chen J, Chen Y, Pelicano H, Bernatchez C, Gopal YNV, Heffernan TP, Hu J, Wang J, Amaria RN, Garraway LA, Huang P, Yang P, Wistuba II, Woodman SE, Roszik J, Davis RE, Davies MA, Heymach JV, Hwu P, Peng W. Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy. Cell Metab. 2018 May 01; 27(5):977-987.e4. PMID: 29628419.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    59. Lin W, Xie J, Xu N, Huang L, Xu A, Li H, Li C, Gao Y, Watanabe M, Liu C, Huang P. Glaucocalyxin A induces G2/M cell cycle arrest and apoptosis through the PI3K/Akt pathway in human bladder cancer cells. Int J Biol Sci. 2018; 14(4):418-426. PMID: 29725263.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    60. Hou GX, Liu PP, Zhang S, Yang M, Liao J, Yang J, Hu Y, Jiang WQ, Wen S, Huang P. Elimination of stem-like cancer cell side-population by auranofin through modulation of ROS and glycolysis. Cell Death Dis. 2018 01 24; 9(2):89. PMID: 29367724.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    61. Wang J, Li XB, Huang P, Huang MY, Gu XJ. Change of Peripheral Blood Treg/Thl7 in Cognitive Impairment with Chronic Renal Failure Patients. Cell Physiol Biochem. 2018; 45(1):281-290. PMID: 29402868.
      Citations:    Fields:    Translation:HumansCells
    62. Saha N, Wang H, Zhang S, Du Y, Zhu D, Hu Y, Huang P, Wen S. Domino Carbopalladation/C-H Activation as a Quick Access to Polycyclic Frameworks. Org Lett. 2018 02 02; 20(3):712-715. PMID: 29320206.
      Citations:    Fields:    
    63. Wang Y, Chen Y, Guan L, Zhang H, Huang Y, Johnson CH, Wu Z, Gonzalez FJ, Yu A, Huang P, Wang Y, Yang S, Chen P, Fan X, Huang M, Bi H. Carnitine palmitoyltransferase 1C regulates cancer cell senescence through mitochondria-associated metabolic reprograming. Cell Death Differ. 2018 03; 25(4):735-748. PMID: 29317762.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    64. Wen S, Wang J, Liu P, Li Y, Lu W, Hu Y, Liu J, He Z, Huang P. Novel combination of histone methylation modulators with therapeutic synergy against acute myeloid leukemia in vitro and in vivo. Cancer Lett. 2018 01 28; 413:35-45. PMID: 29069576.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    65. Miao X, Yang W, Feng T, Lin J, Huang P. Drug nanocrystals for cancer therapy. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2018 05; 10(3):e1499. PMID: 29044971.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    66. Chen DL, Lu YX, Zhang JX, Wei XL, Wang F, Zeng ZL, Pan ZZ, Yuan YF, Wang FH, Pelicano H, Chiao PJ, Huang P, Xie D, Li YH, Ju HQ, Xu RH. Long non-coding RNA UICLM promotes colorectal cancer liver metastasis by acting as a ceRNA for microRNA-215 to regulate ZEB2 expression. Theranostics. 2017; 7(19):4836-4849. PMID: 29187907.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    67. Lin H, Zhou Z, Zhong W, Huang P, Ma N, Zhang Y, Zhou C, Lai Y, Huang S, An H, Sun X, Gao L, Lv Z. Naringenin inhibits alcoholic injury by improving lipid metabolism and reducing apoptosis in zebrafish larvae. Oncol Rep. 2017 Nov; 38(5):2877-2884. PMID: 29048675.
      Citations: 4     Fields:    Translation:HumansAnimals
    68. Huang P, Park S, Yan R, Lee J, Chu LC, Lin CT, Hussien A, Rathmell J, Thomas B, Chen C, Hales R, Ettinger DS, Brock M, Hu P, Fishman EK, Gabrielson E, Lam S. Added Value of Computer-aided CT Image Features for Early Lung Cancer Diagnosis with Small Pulmonary Nodules: A Matched Case-Control Study. Radiology. 2018 01; 286(1):286-295. PMID: 28872442.
      Citations: 19     Fields:    Translation:Humans
    69. Jin Q, Zhu W, Jiang D, Zhang R, Kutyreff CJ, Engle JW, Huang P, Cai W, Liu Z, Cheng L. Ultra-small iron-gallic acid coordination polymer nanoparticles for chelator-free labeling of 64Cu and multimodal imaging-guided photothermal therapy. Nanoscale. 2017 Aug 31; 9(34):12609-12617. PMID: 28825066.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    70. Chen DL, Chen LZ, Lu YX, Zhang DS, Zeng ZL, Pan ZZ, Huang P, Wang FH, Li YH, Ju HQ, Xu RH. Long noncoding RNA XIST expedites metastasis and modulates epithelial-mesenchymal transition in colorectal cancer. Cell Death Dis. 2017 08 24; 8(8):e3011. PMID: 28837144.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    71. Wang J, Luo B, Li X, Lu W, Yang J, Hu Y, Huang P, Wen S. Inhibition of cancer growth in vitro and in vivo by a novel ROS-modulating agent with ability to eliminate stem-like cancer cells. Cell Death Dis. 2017 06 22; 8(6):e2887. PMID: 28640251.
      Citations: 18     Fields:    Translation:AnimalsCells
    72. Cui Q, Wen S, Huang P. Targeting cancer cell mitochondria as a therapeutic approach: recent updates. Future Med Chem. 2017 06; 9(9):929-949. PMID: 28636410.
      Citations: 14     Fields:    Translation:HumansCells
    73. Liu Y, Tang D, Zhang K, Huang P, Wang Z, Zhu K, Li Z, Yuan L, Fan J, Zhou Y, Song B. Tuning Surface Energy of Conjugated Polymers via Fluorine Substitution of Side Alkyl Chains: Influence on Phase Separation of Thin Films and Performance of Polymer Solar Cells. ACS Omega. 2017 Jun 30; 2(6):2489-2498. PMID: 31457595.
      Citations:    
    74. Ying X, Chen J, Huang X, Huang P, Yan S. Effect of AXL on the epithelial-to-mesenchymal transition in non-small cell lung cancer. Exp Ther Med. 2017 Jul; 14(1):785-790. PMID: 28673000.
      Citations:    
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    145. Li Y, Fu L, Li JB, Qin Y, Zeng TT, Zhou J, Zeng ZL, Chen J, Cao TT, Ban X, Qian C, Cai Z, Xie D, Huang P, Guan XY. Increased expression of EIF5A2, via hypoxia or gene amplification, contributes to metastasis and angiogenesis of esophageal squamous cell carcinoma. Gastroenterology. 2014 Jun; 146(7):1701-13.e9. PMID: 24561231.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    146. Luo Y, Gou X, Huang P, Mou C. Prostate cancer antigen 3 test for prostate biopsy decision: a systematic review and meta analysis. Chin Med J (Engl). 2014; 127(9):1768-74. PMID: 24791889.
      Citations: 2     Fields:    Translation:Humans
    147. Watanabe M, Sakaguchi M, Kinoshita R, Kaku H, Ariyoshi Y, Ueki H, Tanimoto R, Ebara S, Ochiai K, Futami J, Li SA, Huang P, Nasu Y, Huh NH, Kumon H. A novel gene expression system strongly enhances the anticancer effects of a REIC/Dkk-3-encoding adenoviral vector. Oncol Rep. 2014 Mar; 31(3):1089-95. PMID: 24398705.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    148. Huang P, Lin J, Li W, Rong P, Wang Z, Wang S, Wang X, Sun X, Aronova M, Niu G, Leapman RD, Nie Z, Chen X. Biodegradable gold nanovesicles with an ultrastrong plasmonic coupling effect for photoacoustic imaging and photothermal therapy. Angew Chem Int Ed Engl. 2013 Dec 23; 52(52):13958-13964. PMID: 24318645.
      Citations: 85     Fields:    Translation:Humans
    149. Li M, Luo B, Liu Q, Hu Y, Ganesan A, Huang P, Wen S. Synthesis of N-acyl-N,O-acetals mediated by titanium ethoxide. Org Lett. 2014 Jan 03; 16(1):10-3. PMID: 24308842.
      Citations: 3     Fields:    Translation:Cells
    150. Zeng ZL, Luo HY, Yang J, Wu WJ, Chen DL, Huang P, Xu RH. Overexpression of the circadian clock gene Bmal1 increases sensitivity to oxaliplatin in colorectal cancer. Clin Cancer Res. 2014 Feb 15; 20(4):1042-52. PMID: 24277452.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    151. Li X, Lu W, Hu Y, Wen S, Qian C, Wu W, Huang P. Effective inhibition of nasopharyngeal carcinoma in vitro and in vivo by targeting glycolysis with oxamate. Int J Oncol. 2013 Nov; 43(5):1710-8. PMID: 23982861.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    152. Zhu D, Chen M, Li M, Luo B, Zhao Y, Huang P, Xue F, Rapposelli S, Pi R, Wen S. Discovery of novel N-substituted carbazoles as neuroprotective agents with potent anti-oxidative activity. Eur J Med Chem. 2013 Oct; 68:81-8. PMID: 23973819.
      Citations: 2     Fields:    Translation:AnimalsCells
    153. Lin J, Wang S, Huang P, Wang Z, Chen S, Niu G, Li W, He J, Cui D, Lu G, Chen X, Nie Z. Photosensitizer-loaded gold vesicles with strong plasmonic coupling effect for imaging-guided photothermal/photodynamic therapy. ACS Nano. 2013 Jun 25; 7(6):5320-9. PMID: 23721576.
      Citations: 87     Fields:    Translation:HumansAnimalsCells
    154. Wang Z, Zhang X, Huang P, Zhao W, Liu D, Nie L, Yue X, Wang S, Ma Y, Kiesewetter D, Niu G, Chen X. Dual-factor triggered fluorogenic nanoprobe for ultrahigh contrast and subdiffraction fluorescence imaging. Biomaterials. 2013 Aug; 34(26):6194-201. PMID: 23721793.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    155. Chen S, Huang P, Wang Z, Wang Z, Swierczewska M, Niu G, Cui D, Chen X. Self-assembly of gold nanoparticles to silver microspheres as highly efficient 3D SERS substrates. Nanoscale Res Lett. 2013 Apr 12; 8(1):168. PMID: 23587323.
      Citations:    
    156. Wang P, Mai C, Wei YL, Zhao JJ, Hu YM, Zeng ZL, Yang J, Lu WH, Xu RH, Huang P. Decreased expression of the mitochondrial metabolic enzyme aconitase (ACO2) is associated with poor prognosis in gastric cancer. Med Oncol. 2013 Jun; 30(2):552. PMID: 23550275.
      Citations: 17     Fields:    Translation:Humans
    157. Schauer IG, Zhang J, Xing Z, Guo X, Mercado-Uribe I, Sood AK, Huang P, Liu J. Interleukin-1ß promotes ovarian tumorigenesis through a p53/NF-?B-mediated inflammatory response in stromal fibroblasts. Neoplasia. 2013 Apr; 15(4):409-20. PMID: 23555186.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    158. Huang P, Lin J, Wang S, Zhou Z, Li Z, Wang Z, Zhang C, Yue X, Niu G, Yang M, Cui D, Chen X. Photosensitizer-conjugated silica-coated gold nanoclusters for fluorescence imaging-guided photodynamic therapy. Biomaterials. 2013 Jun; 34(19):4643-54. PMID: 23523428.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    159. Wang S, Huang P, Nie L, Xing R, Liu D, Wang Z, Lin J, Chen S, Niu G, Lu G, Chen X. Single continuous wave laser induced photodynamic/plasmonic photothermal therapy using photosensitizer-functionalized gold nanostars. . 2013 Jun 11; 25(22):3055-61. PMID: 23404693.
      Citations:    
    160. Chen L, Riaz Ahmed KB, Huang P, Jin Z. Design, synthesis, and biological evaluation of truncated superstolide A. Angew Chem Int Ed Engl. 2013 Mar 18; 52(12):3446-9. PMID: 23404936.
      Citations:    Fields:    Translation:HumansCells
    161. Trachootham D, Chen G, Zhang W, Lu W, Zhang H, Liu J, Huang P. Loss of p53 in stromal fibroblasts promotes epithelial cell invasion through redox-mediated ICAM1 signal. Free Radic Biol Med. 2013 May; 58:1-13. PMID: 23376231.
      Citations: 6     Fields:    Translation:HumansCells
    162. Zhang W, Feng L, Pelicano H, Huang P. [Resistance of chronic lymphocytic leukemia cells in apoptosis: key role of stromal cells in maintaining the redox potential of CLL cells]. Med Sci (Paris). 2013 Jan; 29(1):36-8. PMID: 23351693.
      Citations:    Fields:    Translation:HumansAnimalsCells
    163. Yuan S, Wang F, Chen G, Zhang H, Feng L, Wang L, Colman H, Keating MJ, Li X, Xu RH, Wang J, Huang P. Effective elimination of cancer stem cells by a novel drug combination strategy. Stem Cells. 2013 Jan; 31(1):23-34. PMID: 23132831.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    164. Wen S, Zhu D, Huang P. Targeting cancer cell mitochondria as a therapeutic approach. Future Med Chem. 2013 Jan; 5(1):53-67. PMID: 23256813.
      Citations: 48     Fields:    Translation:HumansCells
    165. Garcia-Prieto C, Riaz Ahmed KB, Chen Z, Zhou Y, Hammoudi N, Kang Y, Lou C, Mei Y, Jin Z, Huang P. Effective killing of leukemia cells by the natural product OSW-1 through disruption of cellular calcium homeostasis. J Biol Chem. 2013 Feb 01; 288(5):3240-50. PMID: 23250754.
      Citations: 11     Fields:    Translation:HumansCells
    166. Wu WJ, Zhang Y, Zeng ZL, Li XB, Hu KS, Luo HY, Yang J, Huang P, Xu RH. ß-phenylethyl isothiocyanate reverses platinum resistance by a GSH-dependent mechanism in cancer cells with epithelial-mesenchymal transition phenotype. Biochem Pharmacol. 2013 Feb 15; 85(4):486-96. PMID: 23219523.
      Citations: 20     Fields:    Translation:HumansAnimals
    167. Ma J, Huang P, He M, Pan L, Zhou Z, Feng L, Gao G, Cui D. Folic acid-conjugated LaF3:Yb,Tm@SiO2 nanoprobes for targeting dual-modality imaging of upconversion luminescence and X-ray computed tomography. J Phys Chem B. 2012 Dec 06; 116(48):14062-70. PMID: 23134318.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    168. Wang Z, Huang P, Bhirde A, Jin A, Ma Y, Niu G, Neamati N, Chen X. A nanoscale graphene oxide-peptide biosensor for real-time specific biomarker detection on the cell surface. Chem Commun (Camb). 2012 Oct 09; 48(78):9768-70. PMID: 22919703.
      Citations: 12     Fields:    Translation:HumansCells
    169. Li JG, Chen C, Huang P, Wang Y, Liu-Chen LY. 14-3-3? Protein regulates anterograde transport of the human ?-opioid receptor (hKOPR). J Biol Chem. 2012 Nov 02; 287(45):37778-92. PMID: 22989890.
      Citations: 4     Fields:    Translation:AnimalsCells
    170. Xu RH, Huang P. A new role for PHD in chemotherapy. Cancer Cell. 2012 Aug 14; 22(2):143-4. PMID: 22897845.
      Citations:    Fields:    Translation:Animals
    171. Hu NJ, Huang P, Liu JH, Shi XF, Ma DY, Liu Y. Source apportionment of polycyclic aromatic hydrocarbons in surface sediments of the Bohai Sea, China. Environ Sci Pollut Res Int. 2013 Feb; 20(2):1031-40. PMID: 22855357.
      Citations: 5     Fields:    Translation:PHPublic Health
    172. Huang P, Lin J, Wang X, Wang Z, Zhang C, He M, Wang K, Chen F, Li Z, Shen G, Cui D, Chen X. Light-triggered theranostics based on photosensitizer-conjugated carbon dots for simultaneous enhanced-fluorescence imaging and photodynamic therapy. . 2012 Sep 25; 24(37):5104-10. PMID: 22718562.
      Citations:    
    173. Lu W, Hu Y, Chen G, Chen Z, Zhang H, Wang F, Feng L, Pelicano H, Wang H, Keating MJ, Liu J, McKeehan W, Wang H, Luo Y, Huang P. Novel role of NOX in supporting aerobic glycolysis in cancer cells with mitochondrial dysfunction and as a potential target for cancer therapy. PLoS Biol. 2012; 10(5):e1001326. PMID: 22589701.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    174. Honeychurch J, Alduaij W, Azizyan M, Cheadle EJ, Pelicano H, Ivanov A, Huang P, Cragg MS, Illidge TM. Antibody-induced nonapoptotic cell death in human lymphoma and leukemia cells is mediated through a novel reactive oxygen species-dependent pathway. Blood. 2012 Apr 12; 119(15):3523-33. PMID: 22354003.
      Citations: 37     Fields:    Translation:HumansCells
    175. Zhang W, Trachootham D, Liu J, Chen G, Pelicano H, Garcia-Prieto C, Lu W, Burger JA, Croce CM, Plunkett W, Keating MJ, Huang P. Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukaemia. Nat Cell Biol. 2012 Feb 19; 14(3):276-86. PMID: 22344033.
      Citations: 119     Fields:    Translation:HumansAnimalsCells
    176. Tang Z, Yuan S, Hu Y, Zhang H, Wu W, Zeng Z, Yang J, Yun J, Xu R, Huang P. Over-expression of GAPDH in human colorectal carcinoma as a preferred target of 3-bromopyruvate propyl ester. J Bioenerg Biomembr. 2012 Feb; 44(1):117-25. PMID: 22350014.
      Citations: 22     Fields:    Translation:Humans
    177. Keizman D, Ish-Shalom M, Huang P, Eisenberger MA, Pili R, Hammers H, Carducci MA. The association of pre-treatment neutrophil to lymphocyte ratio with response rate, progression free survival and overall survival of patients treated with sunitinib for metastatic renal cell carcinoma. Eur J Cancer. 2012 Jan; 48(2):202-8. PMID: 22018713.
      Citations: 76     Fields:    Translation:HumansCells
    178. Feng L, Gao G, Huang P, Wang X, Zhang C, Zhang J, Guo S, Cui D. Preparation of Pt Ag alloy nanoisland/graphene hybrid composites and its high stability and catalytic activity in methanol electro-oxidation. Nanoscale Res Lett. 2011 Oct 07; 6(1):551. PMID: 21982417.
      Citations:    
    179. Chen G, Chen Z, Hu Y, Huang P. Inhibition of mitochondrial respiration and rapid depletion of mitochondrial glutathione by ß-phenethyl isothiocyanate: mechanisms for anti-leukemia activity. Antioxid Redox Signal. 2011 Dec 15; 15(12):2911-21. PMID: 21827296.
      Citations: 28     Fields:    Translation:HumansCells
    180. Wang J, Han F, Wu J, Lee SW, Chan CH, Wu CY, Yang WL, Gao Y, Zhang X, Jeong YS, Moten A, Samaniego F, Huang P, Liu Q, Zeng YX, Lin HK. The role of Skp2 in hematopoietic stem cell quiescence, pool size, and self-renewal. Blood. 2011 Nov 17; 118(20):5429-38. PMID: 21931116.
      Citations: 20     Fields:    Translation:AnimalsCells
    181. Hu Y, Lu W, Chen G, Wang P, Chen Z, Zhou Y, Ogasawara M, Trachootham D, Feng L, Pelicano H, Chiao PJ, Keating MJ, Garcia-Manero G, Huang P. K-ras(G12V) transformation leads to mitochondrial dysfunction and a metabolic switch from oxidative phosphorylation to glycolysis. Cell Res. 2012 Feb; 22(2):399-412. PMID: 21876558.
      Citations: 91     Fields:    Translation:HumansAnimalsCells
    182. Hammoudi N, Ahmed KB, Garcia-Prieto C, Huang P. Metabolic alterations in cancer cells and therapeutic implications. Chin J Cancer. 2011 Aug; 30(8):508-25. PMID: 21801600.
      Citations: 25     Fields:    Translation:HumansCells
    183. Zhou Y, Zhou Y, Shingu T, Feng L, Chen Z, Ogasawara M, Keating MJ, Kondo S, Huang P. Metabolic alterations in highly tumorigenic glioblastoma cells: preference for hypoxia and high dependency on glycolysis. J Biol Chem. 2011 Sep 16; 286(37):32843-53. PMID: 21795717.
      Citations: 85     Fields:    Translation:HumansAnimalsCells
    184. Huang P, Kishida S, Cao D, Murakami-Tonami Y, Mu P, Nakaguro M, Koide N, Takeuchi I, Onishi A, Kadomatsu K. The neuronal differentiation factor NeuroD1 downregulates the neuronal repellent factor Slit2 expression and promotes cell motility and tumor formation of neuroblastoma. Cancer Res. 2011 Apr 15; 71(8):2938-48. PMID: 21349947.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    185. Akers LJ, Fang W, Levy AG, Franklin AR, Huang P, Zweidler-McKay PA. Targeting glycolysis in leukemia: a novel inhibitor 3-BrOP in combination with rapamycin. Leuk Res. 2011 Jun; 35(6):814-20. PMID: 21316758.
      Citations: 21     Fields:    Translation:HumansCells
    186. Hu NJ, Luo YM, Huang P, Hu TD, Xie YN, Wu ZY, Shi XF. [X-ray absorption spectroscopic evidence for the formation of Pb(II) inner-sphere adsorption complexes and precipitates at the alkaline soil-water interface]. Guang Pu Xue Yu Guang Pu Fen Xi. 2011 Feb; 31(2):560-4. PMID: 21510427.
      Citations:    Fields:    
    187. Zhang W, Huang P. Cancer-stromal interactions: role in cell survival, metabolism and drug sensitivity. . 2011 Jan 15; 11(2):150-6. PMID: 21191189.
      Citations:    
    188. Hu ZY, Wang J, Cheng G, Zhu XF, Huang P, Yang D, Zeng YX. Apogossypolone targets mitochondria and light enhances its anticancer activity by stimulating generation of singlet oxygen and reactive oxygen species. Chin J Cancer. 2011 Jan; 30(1):41-53. PMID: 21192843.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    189. Hu NJ, Huang P, Luo YM, Hu TD, Xie YN, Wu ZY. [X-ray absorption fine structure (XAFS) study of the effects of pH on Pb(II) sorption by soil]. Guang Pu Xue Yu Guang Pu Fen Xi. 2010 Dec; 30(12):3425-9. PMID: 21322254.
      Citations:    Fields:    
    190. Qu Y, Wang J, Ray PS, Guo H, Huang J, Shin-Sim M, Bukoye BA, Liu B, Lee AV, Lin X, Huang P, Martens JW, Giuliano AE, Zhang N, Cheng NH, Cui X. Thioredoxin-like 2 regulates human cancer cell growth and metastasis via redox homeostasis and NF-?B signaling. J Clin Invest. 2011 Jan; 121(1):212-25. PMID: 21123948.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    191. Qiu MZ, Li ZH, Zhou ZW, Li YH, Wang ZQ, Wang FH, Huang P, Aziz F, Wang DY, Xu RH. Detection of carcinoembryonic antigen messenger RNA in blood using quantitative real-time reverse transcriptase-polymerase chain reaction to predict recurrence of gastric adenocarcinoma. J Transl Med. 2010 Oct 31; 8:107. PMID: 21040522.
      Citations: 11     Fields:    Translation:HumansCells
    192. Levy AG, Zage PE, Akers LJ, Ghisoli ML, Chen Z, Fang W, Kannan S, Graham T, Zeng L, Franklin AR, Huang P, Zweidler-McKay PA. The combination of the novel glycolysis inhibitor 3-BrOP and rapamycin is effective against neuroblastoma. Invest New Drugs. 2012 Feb; 30(1):191-9. PMID: 20890785.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    193. Carew JS, Medina EC, Esquivel JA, Mahalingam D, Swords R, Kelly K, Zhang H, Huang P, Mita AC, Mita MM, Giles FJ, Nawrocki ST. Autophagy inhibition enhances vorinostat-induced apoptosis via ubiquitinated protein accumulation. J Cell Mol Med. 2010 Oct; 14(10):2448-59. PMID: 19583815.
      Citations: 87     Fields:    Translation:HumansAnimalsCells
    194. Lu W, Pelicano H, Huang P. Cancer metabolism: is glutamine sweeter than glucose? Cancer Cell. 2010 Sep 14; 18(3):199-200. PMID: 20832746.
      Citations: 48     Fields:    
    195. Chen G, Wang F, Trachootham D, Huang P. Preferential killing of cancer cells with mitochondrial dysfunction by natural compounds. Mitochondrion. 2010 Nov; 10(6):614-25. PMID: 20713185.
      Citations: 24     Fields:    Translation:HumansCells
    196. Li Z, Huang P, Lin J, He R, Liu B, Zhang X, Yang S, Xi P, Zhang X, Ren Q, Cui D. Arginine-glycine-aspartic acid-conjugated dendrimer-modified quantum dots for targeting and imaging melanoma. J Nanosci Nanotechnol. 2010 Aug; 10(8):4859-67. PMID: 21125820.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    197. Luo Y, Yang C, Lu W, Xie R, Jin C, Huang P, Wang F, McKeehan WL. Metabolic regulator betaKlotho interacts with fibroblast growth factor receptor 4 (FGFR4) to induce apoptosis and inhibit tumor cell proliferation. J Biol Chem. 2010 Sep 24; 285(39):30069-78. PMID: 20657013.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    198. Hu Y, Lu W, Chen G, Zhang H, Jia Y, Wei Y, Yang H, Zhang W, Fiskus W, Bhalla K, Keating M, Huang P, Garcia-Manero G. Overcoming resistance to histone deacetylase inhibitors in human leukemia with the redox modulating compound ß-phenylethyl isothiocyanate. Blood. 2010 Oct 14; 116(15):2732-41. PMID: 20566897.
      Citations: 41     Fields:    Translation:HumansCells
    199. Luo HY, Wei W, Shi YX, Chen XQ, Li YH, Wang F, Qiu MZ, Li FH, Yan SL, Zeng MS, Huang P, Xu RH. Cetuximab enhances the effect of oxaliplatin on hypoxic gastric cancer cell lines. Oncol Rep. 2010 Jun; 23(6):1735-45. PMID: 20428833.
      Citations: 13     Fields:    Translation:HumansCells
    200. Wei X, Guo W, Wu S, Wang L, Huang P, Liu J, Fang B. Oxidative stress in NSC-741909-induced apoptosis of cancer cells. J Transl Med. 2010 Apr 16; 8:37. PMID: 20398386.
      Citations: 18     Fields:    Translation:HumansCells
    201. Li Z, Huang P, Zhang X, Lin J, Yang S, Liu B, Gao F, Xi P, Ren Q, Cui D. RGD-conjugated dendrimer-modified gold nanorods for in vivo tumor targeting and photothermal therapy. Mol Pharm. 2010 Feb 01; 7(1):94-104. PMID: 19891496.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    202. Wang F, Ogasawara MA, Huang P. Small mitochondria-targeting molecules as anti-cancer agents. Mol Aspects Med. 2010 Feb; 31(1):75-92. PMID: 19995573.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    203. Chen J, Watanabe M, Huang P, Sakaguchi M, Ochiai K, Nasu Y, Ouchida M, Huh NH, Shimizu K, Kashiwakura Y, Kaku H, Kumon H. REIC/Dkk-3 stable transfection reduces the malignant phenotype of mouse prostate cancer RM9 cells. Int J Mol Med. 2009 Dec; 24(6):789-94. PMID: 19885619.
      Citations: 6     Fields:    Translation:AnimalsCells
    204. Kang Y, Lou C, Ahmed KB, Huang P, Jin Z. Synthesis of biotinylated OSW-1. Bioorg Med Chem Lett. 2009 Sep 01; 19(17):5166-8. PMID: 19640708.
      Citations:    Fields:    Translation:HumansCells
    205. Trachootham D, Alexandre J, Huang P. Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nat Rev Drug Discov. 2009 Jul; 8(7):579-91. PMID: 19478820.
      Citations: 1031     Fields:    Translation:HumansAnimalsCells
    206. Chen G, Izzo J, Demizu Y, Wang F, Guha S, Wu X, Hung MC, Ajani JA, Huang P. Different redox states in malignant and nonmalignant esophageal epithelial cells and differential cytotoxic responses to bile acid and honokiol. Antioxid Redox Signal. 2009 May; 11(5):1083-95. PMID: 19187006.
      Citations: 10     Fields:    Translation:HumansCells
    207. Chen Z, Zhang H, Lu W, Huang P. Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-bromopyruvate. Biochim Biophys Acta. 2009 May; 1787(5):553-60. PMID: 19285479.
      Citations: 72     Fields:    Translation:HumansCells
    208. Pelicano H, Lu W, Zhou Y, Zhang W, Chen Z, Hu Y, Huang P. Mitochondrial dysfunction and reactive oxygen species imbalance promote breast cancer cell motility through a CXCL14-mediated mechanism. Cancer Res. 2009 Mar 15; 69(6):2375-83. PMID: 19276362.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    209. Trachootham D, Lu W, Ogasawara MA, Nilsa RD, Huang P. Redox regulation of cell survival. Antioxid Redox Signal. 2008 Aug; 10(8):1343-74. PMID: 18522489.
      Citations: 393     Fields:    Translation:HumansAnimalsCells
    210. Nawrocki ST, Carew JS, Maclean KH, Courage JF, Huang P, Houghton JA, Cleveland JL, Giles FJ, McConkey DJ. Myc regulates aggresome formation, the induction of Noxa, and apoptosis in response to the combination of bortezomib and SAHA. Blood. 2008 Oct 01; 112(7):2917-26. PMID: 18641367.
      Citations: 43     Fields:    Translation:HumansCells
    211. Huang P, Wang CY, Gou SM, Wu HS, Liu T, Xiong JX. Isolation and biological analysis of tumor stem cells from pancreatic adenocarcinoma. World J Gastroenterol. 2008 Jun 28; 14(24):3903-7. PMID: 18609717.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    212. Trachootham D, Zhang H, Zhang W, Feng L, Du M, Zhou Y, Chen Z, Pelicano H, Plunkett W, Wierda WG, Keating MJ, Huang P. Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism. Blood. 2008 Sep 01; 112(5):1912-22. PMID: 18574029.
      Citations: 73     Fields:    Translation:HumansCells
    213. Wei W, Wen L, Huang P, Zhang Z, Chen Y, Xiao A, Huang H, Zhu Z, Zhang B, Lin S. Gfi1.1 regulates hematopoietic lineage differentiation during zebrafish embryogenesis. Cell Res. 2008 Jun; 18(6):677-85. PMID: 18504458.
      Citations: 8     Fields:    Translation:AnimalsCells
    214. Demizu Y, Sasaki R, Trachootham D, Pelicano H, Colacino JA, Liu J, Huang P. Alterations of cellular redox state during NNK-induced malignant transformation and resistance to radiation. Antioxid Redox Signal. 2008 May; 10(5):951-61. PMID: 18257743.
      Citations: 6     Fields:    Translation:HumansCells
    215. Yen CJ, Izzo JG, Lee DF, Guha S, Wei Y, Wu TT, Chen CT, Kuo HP, Hsu JM, Sun HL, Chou CK, Buttar NS, Wang KK, Huang P, Ajani J, Hung MC. Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma. Cancer Res. 2008 Apr 15; 68(8):2632-40. PMID: 18413730.
      Citations: 24     Fields:    Translation:Humans
    216. Sasaki R, Suzuki Y, Yonezawa Y, Ota Y, Okamoto Y, Demizu Y, Huang P, Yoshida H, Sugimura K, Mizushina Y. DNA polymerase gamma inhibition by vitamin K3 induces mitochondria-mediated cytotoxicity in human cancer cells. Cancer Sci. 2008 May; 99(5):1040-8. PMID: 18312466.
      Citations: 16     Fields:    Translation:HumansCells
    217. Wang Y, Zhang Y, Zhang X, Huang P, Xiao S, Wang Z, Liu Z, Liu B, Lu N, Mao K. A single posterior approach for multilevel modified vertebral column resection in adults with severe rigid congenital kyphoscoliosis: a retrospective study of 13 cases. Eur Spine J. 2008 Mar; 17(3):361-372. PMID: 18172699.
      Citations: 26     Fields:    Translation:Humans
    218. Chen Z, Lu W, Garcia-Prieto C, Huang P. The Warburg effect and its cancer therapeutic implications. J Bioenerg Biomembr. 2007 Jun; 39(3):267-74. PMID: 17551814.
      Citations: 92     Fields:    Translation:HumansAnimalsCells
    219. Alexandre J, Hu Y, Lu W, Pelicano H, Huang P. Novel action of paclitaxel against cancer cells: bystander effect mediated by reactive oxygen species. Cancer Res. 2007 Apr 15; 67(8):3512-7. PMID: 17440056.
      Citations: 103     Fields:    Translation:HumansCells
    220. Carew JS, Nawrocki ST, Kahue CN, Zhang H, Yang C, Chung L, Houghton JA, Huang P, Giles FJ, Cleveland JL. Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl-mediated drug resistance. Blood. 2007 Jul 01; 110(1):313-22. PMID: 17363733.
      Citations: 205     Fields:    Translation:HumansCells
    221. Niu J, Chang Z, Peng B, Xia Q, Lu W, Huang P, Tsao MS, Chiao PJ. Keratinocyte growth factor/fibroblast growth factor-7-regulated cell migration and invasion through activation of NF-kappaB transcription factors. J Biol Chem. 2007 Mar 02; 282(9):6001-11. PMID: 17200110.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    222. Lu W, Ogasawara MA, Huang P. Models of reactive oxygen species in cancer. Drug Discov Today Dis Models. 2007; 4(2):67-73. PMID: 18591999.
      Citations:    
    223. Pelicano H, Xu RH, Du M, Feng L, Sasaki R, Carew JS, Hu Y, Ramdas L, Hu L, Keating MJ, Zhang W, Plunkett W, Huang P. Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism. J Cell Biol. 2006 Dec 18; 175(6):913-23. PMID: 17158952.
      Citations: 149     Fields:    Translation:HumansCells
    224. Trachootham D, Zhou Y, Zhang H, Demizu Y, Chen Z, Pelicano H, Chiao PJ, Achanta G, Arlinghaus RB, Liu J, Huang P. Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate. Cancer Cell. 2006 Sep; 10(3):241-52. PMID: 16959615.
      Citations: 362     Fields:    Translation:HumansAnimalsCells
    225. Achanta G, Modzelewska A, Feng L, Khan SR, Huang P. A boronic-chalcone derivative exhibits potent anticancer activity through inhibition of the proteasome. Mol Pharmacol. 2006 Jul; 70(1):426-33. PMID: 16636137.
      Citations: 16     Fields:    Translation:HumansCells
    226. Zeng Z, Samudio IJ, Zhang W, Estrov Z, Pelicano H, Harris D, Frolova O, Hail N, Chen W, Kornblau SM, Huang P, Lu Y, Mills GB, Andreeff M, Konopleva M. Simultaneous inhibition of PDK1/AKT and Fms-like tyrosine kinase 3 signaling by a small-molecule KP372-1 induces mitochondrial dysfunction and apoptosis in acute myelogenous leukemia. Cancer Res. 2006 Apr 01; 66(7):3737-46. PMID: 16585200.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    227. Nawrocki ST, Carew JS, Pino MS, Highshaw RA, Andtbacka RH, Dunner K, Pal A, Bornmann WG, Chiao PJ, Huang P, Xiong H, Abbruzzese JL, McConkey DJ. Aggresome disruption: a novel strategy to enhance bortezomib-induced apoptosis in pancreatic cancer cells. Cancer Res. 2006 Apr 01; 66(7):3773-81. PMID: 16585204.
      Citations: 92     Fields:    Translation:HumansAnimals
    228. Modzelewska A, Pettit C, Achanta G, Davidson NE, Huang P, Khan SR. Anticancer activities of novel chalcone and bis-chalcone derivatives. Bioorg Med Chem. 2006 May 15; 14(10):3491-5. PMID: 16434201.
      Citations: 37     Fields:    Translation:HumansCells
    229. Chen C, Li JG, Chen Y, Huang P, Wang Y, Liu-Chen LY. GEC1 interacts with the kappa opioid receptor and enhances expression of the receptor. J Biol Chem. 2006 Mar 24; 281(12):7983-93. PMID: 16431922.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    230. Samudio I, Konopleva M, Pelicano H, Huang P, Frolova O, Bornmann W, Ying Y, Evans R, Contractor R, Andreeff M. A novel mechanism of action of methyl-2-cyano-3,12 dioxoolean-1,9 diene-28-oate: direct permeabilization of the inner mitochondrial membrane to inhibit electron transport and induce apoptosis. Mol Pharmacol. 2006 Apr; 69(4):1182-93. PMID: 16410408.
      Citations: 31     Fields:    Translation:HumansCells
    231. Nawrocki ST, Carew JS, Dunner K, Boise LH, Chiao PJ, Huang P, Abbruzzese JL, McConkey DJ. Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells. Cancer Res. 2005 Dec 15; 65(24):11510-9. PMID: 16357160.
      Citations: 101     Fields:    Translation:HumansCells
    232. Nawrocki ST, Carew JS, Pino MS, Highshaw RA, Dunner K, Huang P, Abbruzzese JL, McConkey DJ. Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis. Cancer Res. 2005 Dec 15; 65(24):11658-66. PMID: 16357177.
      Citations: 104     Fields:    Translation:HumansAnimalsCells
    233. Zhou Y, Garcia-Prieto C, Carney DA, Xu RH, Pelicano H, Kang Y, Yu W, Lou C, Kondo S, Liu J, Harris DM, Estrov Z, Keating MJ, Jin Z, Huang P. OSW-1: a natural compound with potent anticancer activity and a novel mechanism of action. J Natl Cancer Inst. 2005 Dec 07; 97(23):1781-5. PMID: 16333034.
      Citations: 17     Fields:    Translation:HumansCells
    234. Zhou C, Huang P, Liu J. The carboxyl-terminal of BRCA1 is required for subnuclear assembly of RAD51 after treatment with cisplatin but not ionizing radiation in human breast and ovarian cancer cells. Biochem Biophys Res Commun. 2005 Oct 28; 336(3):952-60. PMID: 16165098.
      Citations: 9     Fields:    Translation:HumansCells
    235. Hu Y, Rosen DG, Zhou Y, Feng L, Yang G, Liu J, Huang P. Mitochondrial manganese-superoxide dismutase expression in ovarian cancer: role in cell proliferation and response to oxidative stress. J Biol Chem. 2005 Nov 25; 280(47):39485-92. PMID: 16179351.
      Citations: 81     Fields:    Translation:HumansAnimalsCells
    236. Achanta G, Sasaki R, Feng L, Carew JS, Lu W, Pelicano H, Keating MJ, Huang P. Novel role of p53 in maintaining mitochondrial genetic stability through interaction with DNA Pol gamma. EMBO J. 2005 Oct 05; 24(19):3482-92. PMID: 16163384.
      Citations: 112     Fields:    Translation:HumansCells
    237. Carew JS, Nawrocki ST, Krupnik YV, Dunner K, McConkey DJ, Keating MJ, Huang P. Targeting endoplasmic reticulum protein transport: a novel strategy to kill malignant B cells and overcome fludarabine resistance in CLL. Blood. 2006 Jan 01; 107(1):222-31. PMID: 16144803.
      Citations: 36     Fields:    Translation:HumansCells
    238. Liu X, Guo Y, Li Y, Jiang Y, Chubb S, Azuma A, Huang P, Matsuda A, Hittelman W, Plunkett W. Molecular basis for G2 arrest induced by 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine and consequences of checkpoint abrogation. Cancer Res. 2005 Aug 01; 65(15):6874-81. PMID: 16061671.
      Citations: 12     Fields:    Translation:HumansCells
    239. Xu RH, Pelicano H, Zhou Y, Carew JS, Feng L, Bhalla KN, Keating MJ, Huang P. Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia. Cancer Res. 2005 Jan 15; 65(2):613-21. PMID: 15695406.
      Citations: 244     Fields:    Translation:HumansCells
    240. Choi W, Gerner EW, Ramdas L, Dupart J, Carew J, Proctor L, Huang P, Zhang W, Hamilton SR. Combination of 5-fluorouracil and N1,N11-diethylnorspermine markedly activates spermidine/spermine N1-acetyltransferase expression, depletes polyamines, and synergistically induces apoptosis in colon carcinoma cells. J Biol Chem. 2005 Feb 04; 280(5):3295-304. PMID: 15546879.
      Citations: 14     Fields:    Translation:HumansCells
    241. Zhou NN, Zhu XF, Zhou JM, Li MZ, Zhang XS, Huang P, Jiang WQ. 2-Methoxyestradiol induces cell cycle arrest and apoptosis of nasopharyngeal carcinoma cells. Acta Pharmacol Sin. 2004 Nov; 25(11):1515-20. PMID: 15525476.
      Citations: 11     Fields:    Translation:HumansCells
    242. Achanta G, Huang P. Role of p53 in sensing oxidative DNA damage in response to reactive oxygen species-generating agents. Cancer Res. 2004 Sep 01; 64(17):6233-9. PMID: 15342409.
      Citations: 43     Fields:    Translation:HumansCells
    243. Fujioka S, Schmidt C, Sclabas GM, Li Z, Pelicano H, Peng B, Yao A, Niu J, Zhang W, Evans DB, Abbruzzese JL, Huang P, Chiao PJ. Stabilization of p53 is a novel mechanism for proapoptotic function of NF-kappaB. J Biol Chem. 2004 Jun 25; 279(26):27549-59. PMID: 15102862.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    244. Pelicano H, Carney D, Huang P. ROS stress in cancer cells and therapeutic implications. Drug Resist Updat. 2004 Apr; 7(2):97-110. PMID: 15158766.
      Citations: 414     Fields:    
    245. Mone AP, Huang P, Pelicano H, Cheney CM, Green JM, Tso JY, Johnson AJ, Jefferson S, Lin TS, Byrd JC. Hu1D10 induces apoptosis concurrent with activation of the AKT survival pathway in human chronic lymphocytic leukemia cells. Blood. 2004 Mar 01; 103(5):1846-54. PMID: 14630799.
      Citations: 18     Fields:    Translation:HumansCells
    246. Hileman EO, Liu J, Albitar M, Keating MJ, Huang P. Intrinsic oxidative stress in cancer cells: a biochemical basis for therapeutic selectivity. Cancer Chemother Pharmacol. 2004 Mar; 53(3):209-19. PMID: 14610616.
      Citations: 96     Fields:    Translation:HumansCells
    247. Wen X, Wu QP, Ke S, Wallace S, Charnsangavej C, Huang P, Liang D, Chow D, Li C. Improved radiolabeling of PEGylated protein: PEGylated annexin V for noninvasive imaging of tumor apoptosis. Cancer Biother Radiopharm. 2003 Oct; 18(5):819-27. PMID: 14629830.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    248. Carew JS, Zhou Y, Albitar M, Carew JD, Keating MJ, Huang P. Mitochondrial DNA mutations in primary leukemia cells after chemotherapy: clinical significance and therapeutic implications. Leukemia. 2003 Aug; 17(8):1437-47. PMID: 12886229.
      Citations: 59     Fields:    Translation:Humans
    249. Pelicano H, Feng L, Zhou Y, Carew JS, Hileman EO, Plunkett W, Keating MJ, Huang P. Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism. J Biol Chem. 2003 Sep 26; 278(39):37832-9. PMID: 12853461.
      Citations: 120     Fields:    Translation:HumansCells
    250. Zhou Y, Hileman EO, Plunkett W, Keating MJ, Huang P. Free radical stress in chronic lymphocytic leukemia cells and its role in cellular sensitivity to ROS-generating anticancer agents. Blood. 2003 May 15; 101(10):4098-104. PMID: 12531810.
      Citations: 89     Fields:    Translation:HumansCells
    251. Carew JS, Huang P. Mitochondrial defects in cancer. Mol Cancer. 2002 Dec 09; 1:9. PMID: 12513701.
      Citations: 142     Fields:    Translation:Humans
    252. Fu L, Pelicano H, Liu J, Huang P, Lee C. The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo. Cell. 2002 Oct 04; 111(1):41-50. PMID: 12372299.
      Citations: 388     Fields:    Translation:AnimalsCells
    253. Zhou Y, Achanta G, Pelicano H, Gandhi V, Plunkett W, Huang P. Action of (E)-2'-deoxy-2'-(fluoromethylene)cytidine on DNA metabolism: incorporation, excision, and cellular response. Mol Pharmacol. 2002 Jan; 61(1):222-9. PMID: 11752224.
      Citations: 5     Fields:    Translation:HumansCells
    254. Hileman EA, Achanta G, Huang P. Superoxide dismutase: an emerging target for cancer therapeutics. Expert Opin Ther Targets. 2001 Dec; 5(6):697-710. PMID: 12540279.
      Citations: 18     Fields:    
    255. Ballal K, Zhang W, Mukhopadyay T, Huang P. Suppression of mismatched mutation by p53: a mechanism for guarding genomic integrity. J Mol Med (Berl). 2002 Jan; 80(1):25-32. PMID: 11862321.
      Citations:    Fields:    Translation:Humans
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