"Chemokine CXCL12" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CXC chemokine that is chemotactic for T-LYMPHOCYTES and MONOCYTES. It has specificity for CXCR4 RECEPTORS. Two isoforms of CXCL12 are produced by alternative mRNA splicing.
| Descriptor ID |
D054377
|
| MeSH Number(s) |
D12.644.276.374.200.120.600 D12.776.467.374.200.120.600 D23.125.300.120.600 D23.469.200.120.600 D23.529.374.200.120.600
|
| Concept/Terms |
Chemokine CXCL12- Chemokine CXCL12
- CXCL12, Chemokine
- Stromal Cell-Derived Factor 1
- Stromal Cell Derived Factor 1
- CXCL12 Chemokine
- Chemokine, CXCL12
- Chemokine (C-X-C Motif) Ligand 12
- Pre-B-Cell Growth-Stimulating Factor
- Growth-Stimulating Factor, Pre-B-Cell
- Pre B Cell Growth Stimulating Factor
|
Below are MeSH descriptors whose meaning is more general than "Chemokine CXCL12".
Below are MeSH descriptors whose meaning is more specific than "Chemokine CXCL12".
This graph shows the total number of publications written about "Chemokine CXCL12" by people in this website by year, and whether "Chemokine CXCL12" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 3 | 3 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 2 | 2 | 4 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 2 | 3 |
| 2014 | 2 | 3 | 5 |
| 2017 | 2 | 0 | 2 |
| 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Chemokine CXCL12" by people in Profiles.
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Interferon Gamma Mediates Hematopoietic Stem Cell Activation and Niche Relocalization through BST2. Cell Rep. 2020 12 22; 33(12):108530.
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Stromal cell-derived factor 1 regulates in vitro sperm migration towards the cumulus-oocyte complex in cattle. PLoS One. 2020; 15(4):e0232536.
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CXCL12-CXCR4 Axis Is Required for Contact-Mediated Human B Lymphoid and Plasmacytoid Dendritic Cell Differentiation but Not T Lymphoid Generation. J Immunol. 2017 10 01; 199(7):2343-2355.
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Curcumin exhibits anti-tumor effect and attenuates cellular migration via Slit-2 mediated down-regulation of SDF-1 and CXCR4 in endometrial adenocarcinoma cells. J Nutr Biochem. 2017 06; 44:60-70.
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CXCR4 WHIM-like frameshift and nonsense mutations promote ibrutinib resistance but do not supplant MYD88(L265P) -directed survival signalling in Waldenstr?m macroglobulinaemia cells. Br J Haematol. 2015 Mar; 168(5):701-7.
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Plasma stromal cell-derived factor 1a/CXCL12 level predicts long-term adverse cardiovascular outcomes in patients with coronary artery disease. Atherosclerosis. 2015 Jan; 238(1):113-8.
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Plerixafor as a chemosensitizing agent in pediatric acute lymphoblastic leukemia: efficacy and potential mechanisms of resistance to CXCR4 inhibition. Oncotarget. 2014 Oct 15; 5(19):8947-58.
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NADPH oxidase-generated reactive oxygen species are required for stromal cell-derived factor-1a-stimulated angiogenesis. Arterioscler Thromb Vasc Biol. 2014 Sep; 34(9):2023-32.
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The bruton tyrosine kinase inhibitor ibrutinib (PCI-32765) blocks hairy cell leukaemia survival, proliferation and B cell receptor signalling: a new therapeutic approach. Br J Haematol. 2014 Jul; 166(2):177-88.
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Stress-induced CXCR4 promotes migration and invasion of ewing sarcoma. Mol Cancer Res. 2014 Jun; 12(6):953-64.