"Chemokine CXCL12" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CXC chemokine that is chemotactic for T-LYMPHOCYTES and MONOCYTES. It has specificity for CXCR4 RECEPTORS. Two isoforms of CXCL12 are produced by alternative mRNA splicing.
| Descriptor ID |
D054377
|
| MeSH Number(s) |
D12.644.276.374.200.120.600 D12.776.467.374.200.120.600 D23.125.300.120.600 D23.469.200.120.600 D23.529.374.200.120.600
|
| Concept/Terms |
Chemokine CXCL12- Chemokine CXCL12
- CXCL12, Chemokine
- Stromal Cell-Derived Factor 1
- Stromal Cell Derived Factor 1
- CXCL12 Chemokine
- Chemokine, CXCL12
- Chemokine (C-X-C Motif) Ligand 12
- Pre-B-Cell Growth-Stimulating Factor
- Growth-Stimulating Factor, Pre-B-Cell
- Pre B Cell Growth Stimulating Factor
|
Below are MeSH descriptors whose meaning is more general than "Chemokine CXCL12".
Below are MeSH descriptors whose meaning is more specific than "Chemokine CXCL12".
This graph shows the total number of publications written about "Chemokine CXCL12" by people in this website by year, and whether "Chemokine CXCL12" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 3 | 3 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 5 | 5 |
| 2006 | 0 | 5 | 5 |
| 2007 | 0 | 3 | 3 |
| 2008 | 3 | 4 | 7 |
| 2009 | 4 | 4 | 8 |
| 2010 | 5 | 4 | 9 |
| 2011 | 3 | 5 | 8 |
| 2012 | 2 | 2 | 4 |
| 2013 | 3 | 5 | 8 |
| 2014 | 1 | 5 | 6 |
| 2015 | 1 | 2 | 3 |
| 2016 | 0 | 1 | 1 |
| 2017 | 3 | 0 | 3 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 3 | 1 | 4 |
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Below are the most recent publications written about "Chemokine CXCL12" by people in Profiles.
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Interferon Gamma Mediates Hematopoietic Stem Cell Activation and Niche Relocalization through BST2. Cell Rep. 2020 12 22; 33(12):108530.
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Novel Risk Factors for Progression of Diabetic and Nondiabetic CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study. Am J Kidney Dis. 2021 01; 77(1):56-73.e1.
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CXCL12 is required for stirrup-shaped stapes formation during mammalian middle ear development. Dev Dyn. 2020 09; 249(9):1117-1126.
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Expression of Stromal Cell-Derived Factor-1 by Mesenchymal Stromal Cells Impacts Neutrophil Function During Sepsis. Crit Care Med. 2020 05; 48(5):e409-e417.
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Stromal cell-derived factor 1 regulates in vitro sperm migration towards the cumulus-oocyte complex in cattle. PLoS One. 2020; 15(4):e0232536.
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BETP degradation simultaneously targets acute myelogenous leukemia stem cells and the microenvironment. J Clin Invest. 2019 05 01; 129(5):1878-1894.
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Role of CXCL12 and CXCR4 in the pathogenesis of hematological malignancies. Cytokine. 2018 09; 109:11-16.
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CXCL12-CXCR4 Axis Is Required for Contact-Mediated Human B Lymphoid and Plasmacytoid Dendritic Cell Differentiation but Not T Lymphoid Generation. J Immunol. 2017 10 01; 199(7):2343-2355.
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A hypoxia response element in the Vegfa promoter is required for basal Vegfa expression in skin and for optimal granulation tissue formation during wound healing in mice. PLoS One. 2017; 12(7):e0180586.
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Curcumin exhibits anti-tumor effect and attenuates cellular migration via Slit-2 mediated down-regulation of SDF-1 and CXCR4 in endometrial adenocarcinoma cells. J Nutr Biochem. 2017 06; 44:60-70.